Art

J-GLOBAL ID：202102260895667873   Reference number：21A0071027

Trimebutine attenuates high mobility group box 1-receptor for advanced glycation end-products inflammatory signaling pathways

トリメブチンは高度糖化最終産物炎症性シグナル伝達経路のための高移動度グループボックス1受容体を減弱する【JST・京大機械翻訳】

Author (18)： Nakajima Shingo (Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan) ,  Ogawa Natsumi (Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan) ,  Yokoue Natsuki (Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan) ,  Tachibana Haruki (Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan) ,  Tamada Kenya (Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan) ,  Okazawa Miwa (Department of Genomic Medicinal Science, Research Institute for Science and Technology, Organization for Research Advancement, Tokyo University of Science, Noda, Chiba, 278-8510, Japan) ,  Sato Akira (Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan) ,  Oyama Takahiro (Hinoki Shinyaku Co. Ltd., Chiyoda-ku, Tokyo, 102-0084, Japan) ,  Abe Hideaki (Hinoki Shinyaku Co. Ltd., Chiyoda-ku, Tokyo, 102-0084, Japan) ,  Kamiya Takanori (Hinoki Shinyaku Co. Ltd., Chiyoda-ku, Tokyo, 102-0084, Japan) ,  Yoshimori Atsushi (Institute for Theoretical Medicine Inc., Fujisawa, Kanagawa, 251-0012, Japan) ,  Yoshizawa Kazumi (Laboratory of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan) ,  Inoue Shigeaki (Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, Kanagawa, 259-1193, Japan) ,  Yokomizo Takehiko (Department of Biochemistry, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, 113-8421, Japan) ,  Uchiumi Fumiaki (Department of Gene Regulation, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan) ,  Abe Takehiko (Hinoki Shinyaku Co. Ltd., Chiyoda-ku, Tokyo, 102-0084, Japan) ,  Tanuma Sei-ichi (Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan) ,  Tanuma Sei-ichi (Department of Genomic Medicinal Science, Research Institute for Science and Technology, Organization for Research Advancement, Tokyo University of Science, Noda, Chiba, 278-8510, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 533  Issue： 4  Page： 1155-1161  Publication year： 2020 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： We previously identified papav...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=21A0071027&from=J-GLOBAL&jstjournalNo=B0118A") }}

Thesaurus term： interaction ,  *inflammation ,  bone marrow ,  *receptor ,  macrophage ,  TNF ,  up-regulation ,  interleukin 6 ,  inflammatory cytokine ,  RAW264.7 cell ,  ERK
Semi thesaurus term： ドメイン構造 ,  Erk1/2 ,  ファーマコホア ,  キナーゼ , 【Automatic Indexing@JST】

Author keywords (5)： RAGE ,  HMGB1 ,  Inflammation ,  Trimebutine ,  Macrophage

JST classification (2)： Cell physiology in general  (EF02010S) ,  Function of cell components  (EF03060C)

Terms in the title (9)： トリメブチン ,  高度糖化最終産物 ,  炎症 ,  シグナル伝達経路 ,  高移動度 ,  グループ ,  ボックス ,  受容体 ,  減弱