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J-GLOBAL ID：202102265389535978   Reference number：21A0366302

Comparative analyses of site-directed mutagenesis of human melatonin MTNR1A and MTNR1B receptors using a yeast fluorescent biosensor

酵母蛍光バイオセンサを用いたヒトメラトニンMTNR1AとMTNR1B受容体の部位特異的変異誘発の比較分析【JST・京大機械翻訳】

Author (12)： Nakamura Yasuyuki (Engineering Biology Research Center, Kobe University, Kobe, Japan) ,  Nakamura Yasuyuki (Graduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan) ,  Asama Ririka (Graduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan) ,  Tabata Takuya (Graduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan) ,  Morita Kenta (Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, Kobe, Japan) ,  Maruyama Tatsuo (Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, Kobe, Japan) ,  Kondo Akihiko (Engineering Biology Research Center, Kobe University, Kobe, Japan) ,  Kondo Akihiko (Graduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan) ,  Kondo Akihiko (Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, Kobe, Japan) ,  Kondo Akihiko (Center for Sustainable Resource Science, RIKEN, Yokohama, Japan) ,  Ishii Jun (Engineering Biology Research Center, Kobe University, Kobe, Japan) ,  Ishii Jun (Graduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan)
Material： Biotechnology and Bioengineering  (Biotechnol Bioeng)
Volume： 118  Issue： 2  Page： 863-876  Publication year： 2021 
JST Material Number： D0019A  ISSN： 0006-3592  CODEN： BIBIAU  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Melatonin is an indoleamine ne...

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Thesaurus term： *Fluorescence ,  *Yeasts ,  *receptor ,  Pineal Body ,  human ,  Chimera ,  diurnal rhythm ,  Saccharomyces cerevisiae ,  *biosensor ,  Point Mutation ,  *site-directed mutagenesis ,  Saccharomyces ,  Signal Transduction ,  *microorganism ,  Thalamus ,  Ascomycetous yeast ,  fatty acid ,  nitrogen heterocyclic compound ,  carboxamide ,  phenol ether ,  polynuclear aromatic compound
Semi thesaurus term： Saccharomyces ,  cellular signal transduction ,  アゴニスト , 【Automatic Indexing@JST】

Author keywords (5)： G-protein signaling ,  G-protein-coupled receptor ,  melatonin receptor ,  Saccharomyces cerevisiae ,  site-directed mutagenesis

JST classification (5)： Analytical instruments  (CC02020S) ,  Gene expression  (EC02040Q) ,  Microorganism physiology in general  (EG03051L) ,  Molecular genetics in general  (EC02010J) ,  Bioassay  (EA03060N)

Substance index (1)： Melatonin

Terms in the title (8)： 酵母 ,  蛍光 ,  バイオセンサ ,  ヒト ,  メラトニン ,  受容体 ,  部位特異的変異誘発 ,  比較分析