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J-GLOBAL ID：202102274859652825   Reference number：21A0028907

Molecular biological analysis of 5-FU-resistant gastric cancer organoids; KHDRBS3 contributes to the attainment of features of cancer stem cell

5-FU耐性胃癌オルガノイドの分子生物学的解析;KHDRBS3は癌幹細胞の特徴達成に寄与する【JST・京大機械翻訳】

Author (14)： Ukai Shoichi (Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Honma Ririno (Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Sakamoto Naoya (Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Yamamoto Yusuke (Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan) ,  Pham Quoc Thang (Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Harada Kenji (Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Takashima Tsuyoshi (Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Taniyama Daiki (Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Asai Ryuichi (Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Fukada Kaho (Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Naka Kazuhito (Department of Stem Cell Biology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan) ,  Tanabe Kazuaki (Department of Health Care for Adults, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Ohdan Hideki (Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan) ,  Yasui Wataru (Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan)
Material： Oncogene
Volume： 39  Issue： 50  Page： 7265-7278  Publication year： 2020 
JST Material Number： T0406A  ISSN： 0950-9232  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: 5-FU is one of the k...

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Thesaurus term： system engineering ,  cell culture ,  Drug Resistance ,  drug therapy ,  *Molecular Biology ,  Prognosis ,  three dimension ,  *stem cell ,  *stomach tumor ,  multiple drug resistance ,  CD44 antigen ,  DNA microarray ,  *Organoid ,  *Cancer Stem Cell ,  target gene

JST classification (3)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Basic oncology in general  (GE02010R)

Terms in the title (7)： 5-FU ,  耐性 ,  胃 ,  癌オルガノイド ,  分子生物学 ,  解析 ,  癌幹細胞