Art

J-GLOBAL ID：202102278032398028   Reference number：21A0369682

RLTPR Q575E: A novel recurrent gain-of-function mutation in patients with adult T-cell leukemia/lymphoma

RLTPR Q575E:成人T細胞白血病/リンパ腫患者における新規再発性機能獲得突然変異【JST・京大機械翻訳】

Author (17)： Uchida Yuichiro (Department of Hematology and Rheumatology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan) ,  Yoshimitsu Makoto (Department of Hematology and Rheumatology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan) ,  Yoshimitsu Makoto (Department of Hematology and Rheumatology, Kagoshima University Hospital, Kagoshima, Japan) ,  Hachiman Miho (Department of Hematology and Rheumatology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan) ,  Kusano Shuichi (Division of Biological Information Technology, Joint Research Center for Human Retrovirus Infection, Kagoshima University, Kagoshima, Japan) ,  Arima Naosuke (Department of Hematology and Rheumatology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan) ,  Arima Naosuke (Department of Hematology and Rheumatology, Kagoshima University Hospital, Kagoshima, Japan) ,  Shima Kodai (Department of Hematology and Rheumatology, Kagoshima University Hospital, Kagoshima, Japan) ,  Hayashida Maiko (Department of Hematology and Rheumatology, Kagoshima University Hospital, Kagoshima, Japan) ,  Kamada Yuhei (Department of Hematology and Rheumatology, Kagoshima University Hospital, Kagoshima, Japan) ,  Nakamura Daisuke (Department of Hematology and Rheumatology, Kagoshima University Hospital, Kagoshima, Japan) ,  Arai Akihiko (Department of Hematology and Rheumatology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan) ,  Arai Akihiko (Department of Hematology and Rheumatology, Kagoshima University Hospital, Kagoshima, Japan) ,  Tanaka Yuetsu (Laboratory of Hematoimmunology, School of Health Sciences, Faculty of Medicine, Medicine, University of the Ryukyus, Okinawa, Japan) ,  Hara Hiromitsu (Department of Immunology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan) ,  Ishitsuka Kenji (Department of Hematology and Rheumatology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan) ,  Ishitsuka Kenji (Department of Hematology and Rheumatology, Kagoshima University Hospital, Kagoshima, Japan)
Material： European Journal of Haematology  (Eur J Haematol)
Volume： 106  Issue： 2  Page： 221-229  Publication year： 2021 
JST Material Number： B0958B  ISSN： 0902-4441  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： OBJECTIVES: Adult T-cell leuke...

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Thesaurus term： mRNA ,  *mutation ,  carcinogenesis ,  *lymphoma ,  genome ,  *T cell ,  cDNA ,  interleukin 2 ,  *adult T cell leukemia ,  pathogenesis ,  NF-kappaB ,  HTLV1 ,  Jurkat cell
Semi thesaurus term： 悪性腫瘍 ,  エクソーム , 【Automatic Indexing@JST】

Author keywords (5)： adult T-cell leukemia/lymphoma ,  gain-of-function mutation ,  NF-κB signaling ,  RLTPR Q575E ,  T-cell receptor signaling

JST classification (1)： Blood cell tumors(=neoplasms)  (GK04000M)

Terms in the title (7)： 成人T細胞白血病 ,  リンパ腫 ,  患者 ,  再発 ,  性機能 ,  獲得 ,  突然変異