Art

J-GLOBAL ID：202102282153197681   Reference number：21A0295129

The functions and clinical significance of circRNAs in hematological malignancies

血液悪性腫瘍におけるサークRNAの機能と臨床的意義【JST・京大機械翻訳】

Author (14)： Zhou Xiangxiang (Department of Hematology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People’s Republic of China) ,  Zhou Xiangxiang (Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People’s Republic of China) ,  Zhou Xiangxiang (School of Medicine, Shandong University, Jinan, People’s Republic of China) ,  Zhou Xiangxiang (Shandong Provincial Engineering Research Center of Lymphoma, Jinan, People’s Republic of China) ,  Zhou Xiangxiang (Branch of National Clinical Research Center for Hematologic Diseases, Jinan, People’s Republic of China) ,  Zhou Xiangxiang (National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China) ,  Zhan Linquan (Department of Hematology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People’s Republic of China) ,  Huang Kai (Department of Chemotherapy, Cancer Center, Qilu Hospital of Shandong University, Jinan, People’s Republic of China) ,  Wang Xin (Department of Hematology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People’s Republic of China) ,  Wang Xin (Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People’s Republic of China) ,  Wang Xin (School of Medicine, Shandong University, Jinan, People’s Republic of China) ,  Wang Xin (Shandong Provincial Engineering Research Center of Lymphoma, Jinan, People’s Republic of China) ,  Wang Xin (Branch of National Clinical Research Center for Hematologic Diseases, Jinan, People’s Republic of China) ,  Wang Xin (National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China)
Material： Journal of Hematology & Oncology (Web)
Volume： 13  Issue： 1  Page： 1-15  Publication year： 2020 
JST Material Number： U7517A  ISSN： 1756-8722  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： With covalently closed circula...

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Thesaurus term： *RNA ,  *tumor ,  Proteins ,  Drug Resistance ,  targeting ,  therapeutic planning ,  biomarker ,  tumorigenesis ,  Autophagy ,  MicroRNAs ,  molecular mechanism ,  RNA, Circular
Semi thesaurus term： *悪性腫瘍 ,  臨床応用 ,  治療標的 , 【Automatic Indexing@JST】

Author keywords (5)： Circular RNAs ,  Hematological malignancies ,  Tumorigenesis ,  Drug-resistance ,  Biomarker

JST classification (1)： Gene expression  (EC02040Q)

Reference (136)：

• RNA; Circular RNAs are abundant, conserved, and associated with ALU repeats; WR Jeck, JA Sorrentino, K Wang, MK Slevin, CE Burd, J Liu, WF Marzluff, NE Sharpless; 19; 2013; 141-157; 10.1261/rna.035667.112; citation_id=CR1
• Mol Cancer; Roles of circRNAs in the tumour microenvironment; Q Zhang, W Wang, Q Zhou, C Chen, W Yuan, J Liu, X Li, Z Sun; 19; 2020; 14; 10.1186/s12943-019-1125-9; citation_id=CR2
• Nat Rev Mol Cell Biol; The expanding regulatory mechanisms and cellular functions of circular RNAs; LL Chen; 21; 2020; 475-490; 10.1038/s41580-020-0243-y; citation_id=CR3
• Protein Cell; An intriguing RNA species-perspectives of circularized RNA; T Shen, M Han, G Wei, T Ni; 6; 2015; 871-880; 10.1007/s13238-015-0202-0; citation_id=CR4
• Mol Ther; The circular RNA interacts with STAT3, increasing its nuclear translocation and wound repair by modulating Dnmt3a and miR-17 function; ZG Yang, FM Awan, WW Du, Y Zeng, J Lyu, D Wu, S Gupta, W Yang, BB Yang; 25; 2017; 2062-2074; 10.1016/j.ymthe.2017.05.022; citation_id=CR5

Terms in the title (4)： 血液悪性腫瘍 ,  サーク ,  RNA ,  臨床的意義