Art

J-GLOBAL ID：202102286399887566   Reference number：21A0216209

Evaluation of photostability and phototoxicity of esterified derivatives of ubiquinol-10 and their application as prodrugs of reduced coenzyme Q₁₀ for topical administration

ユビキノール-10のエステル化誘導体の光安定性と光毒性の評価および局所投与のための還元補酵素Q_10のプロドラッグとしての応用【JST・京大機械翻訳】

Author (10)： Setoguchi Shuichi (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Nagata-Akaho Nami (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Goto Shotaro (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Yamakawa Hirofumi (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Watase Daisuke (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Terada Kazuki (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Koga Mitsuhisa (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Matsunaga Kazuhisa (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Karube Yoshiharu (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan) ,  Takata Jiro (Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan)
Material： BioFactors
Volume： 46  Issue： 6  Page： 983-994  Publication year： 2020 
JST Material Number： T0787A  ISSN： 0951-6433  CODEN： BIFAEU  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Ubiquinol-10 (UqH-10), the ful...

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Thesaurus term： oxidation ,  *Esterification ,  Hydrolysis ,  *ester ,  superoxide ,  human ,  *ubiquinone ,  Rattus ,  Sunlight ,  bioavailability ,  *local administration ,  *prodrug ,  singlet oxygen ,  antioxidants ,  Myomorpha
Semi thesaurus term： *光安定性 , 【Automatic Indexing@JST】

Author keywords (8)： coenzyme Q ,  drug delivery ,  keratinocyte ,  photostability ,  phototoxicity ,  prodrug ,  skin ,  ubiquinol

JST classification (2)： Biochemical analytical methods  (EA03030G) ,  Enzyme in general  (EB09010D)

Terms in the title (10)： ユビキノール-10 ,  エステル化 ,  誘導体 ,  光安定性 ,  光毒性 ,  評価 ,  局所投与 ,  還元 ,  プロドラッグ ,  応用