Rchr
J-GLOBAL ID：202301012457018610
Update date: Aug. 15, 2024
Mukai Satomi
ムカイ サトミ | Mukai Satomi
Affiliation and department：
Research field (2)：
Cell biology
, Tumor biology
Research theme for competitive and other funds (5)：
- 2022 - 2025 ナノボディを用いた O-GlcNAc 修飾異常による悪性中皮腫進展機構の解明
- 2021 - 2023 合成致死性を利用した新規悪性中皮腫治療標的の探索
- 2019 - 2022 Development of a new therapeutic modality using YAP1/TAZ inhibitors against malignant mesothelioma
- 2017 - 2019 Elucidation of progression mechanism of malignant pleural mesothelioma using co-culture systems
- 2015 - 2017 Elucidation of a novel EMT-MET control mechanism by LATS1 kinase
Papers (18)：
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Tatsuhiro Sato, Ken Akao, Ayuko Sato, Tohru Tsujimura, Satomi Mukai, Yoshitaka Sekido. Aberrant expression of NPPB through YAP1 and TAZ activation in mesothelioma with Hippo pathway gene alterations. Cancer medicine. 2023. 12. 12. 13586-13598
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Koya Suzuki, Masaki Tange, Ryota Yamagishi, Hiroyuki Hanada, Satomi Mukai, Tatsuhiro Sato, Takeshi Tanaka, Tomohiro Akashi, Kenji Kadomatsu, Tohru Maeda, et al. SMG6 regulates DNA damage and cell survival in Hippo pathway kinase LATS2-inactivated malignant mesothelioma. Cell death discovery. 2022. 8. 1. 446-446
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Emi Fujibayashi, Satomi Mukai, Kosuke Torigata, Yumi Ando, Toshihiro Uchihashi, Masami Nozaki, Susumu Tanaka, Masato Okada, Mikihiko Kogo, Hiroshi Nojima, et al. LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells. Scientific reports. 2022. 12. 1. 12363-12363
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Tatsuhiro Sato, Hayao Nakanishi, Ken Akao, Maho Okuda, Satomi Mukai, Tohru Kiyono, Yoshitaka Sekido. Three newly established immortalized mesothelial cell lines exhibit morphological phenotypes corresponding to malignant mesothelioma epithelioid, intermediate, and sarcomatoid types, respectively. Cancer cell international. 2021. 21. 1. 546-546
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Tatsuhiro Sato, Satomi Mukai, Haruna Ikeda, Emi Mishiro-Sato, Ken Akao, Toshiyuki Kobayashi, Okio Hino, Wataru Shimono, Yoshio Shibagaki, Seisuke Hattori, et al. Silencing of SmgGDS, a Novel mTORC1 Inducer That Binds to RHEBs, Inhibits Malignant Mesothelioma Cell Proliferation. Molecular cancer research : MCR. 2021. 19. 5. 921-931
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MISC (37)：
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向井智美, 佐藤龍洋, 亀井保博, 加藤輝, 三城恵美, 三城恵美, 青木正博, 藪田紀一, 廣島健三, 廣島健三. Elucidation of the mechanism of tumor progression via abnormal O-GlcNAcylation of nucleoporins. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
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赤尾 謙, 佐藤 龍洋, 向井 智美, 平野 雅規, 関戸 好孝. 新規TEAD阻害剤の悪性中皮腫細胞株に対する抗腫瘍効果の検討(Investigation of tumor suppressive effects of novel TEAD inhibitors on malignant mesothelioma cell lines). 日本癌学会総会記事. 2022. 81回. P-2363
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向井 智美, 佐藤 龍洋, 三城 恵美, 青木 正博, 藪田 紀一, 関戸 好孝. Hippo経路の破綻した悪性中皮腫におけるO-GlcNAc修飾の亢進を標的とした治療の可能性(Therapeutic potential of targeting enhanced O-GlcNAcylation in malignant mesothelioma with disrupted Hippo pathway). 日本癌学会総会記事. 2022. 81回. P-3046
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向井智美, 佐藤龍洋, 三城恵美, 三城恵美, 藪田紀一, 関戸好孝. Elucidation of the mechanism of tumor progression via abnormal O-GlcNAc modification in malignant mesothelioma. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
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向井智美, 佐藤龍洋, 三城恵美, 青木正博, 藪田紀一, 関戸好孝. Elucidation of the mechanism of tumor progression via abnormal O-GlcNAc modification in malignant mesothelioma. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
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Lectures and oral presentations (1)：
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核と細胞質を繋ぐ核膜孔と様々な生命現象 ヌクレオポリンの翻訳後修飾異常に着目した、YAP/TAZの活性化を伴うがんに対する新規治療の可能性
(日本生化学会大会プログラム・講演要旨集 2023)
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