Rchr
J-GLOBAL ID:201401033119657400   Update date: Mar. 02, 2023

Kinoh Hiromi

キノウ ヒロミ | Kinoh Hiromi
Affiliation and department:
Other affiliations (1):
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/60532728.ja.html
Research field  (2): Experimental pathology ,  Neurosurgery
Research keywords  (6): AAVベクター ,  遺伝子治療 ,  脳神経疾患 ,  神経疾患 ,  ウイルス ,  遺伝子
Research theme for competitive and other funds  (6):
  • 2022 - 2025 経口減感作による組換えAAVの発現効率の改善-筋ジストロフィー治療を目指して
  • 2022 - 2025 デュシェンヌ型筋ジストロフィーの遺伝子治療を目指した免疫応答回避性薬剤の開発
  • 2016 - 2019 IMPROVED GENE TRANSDUCTION WITH RECOMBINANT AAV FOLLOWING IMMUNE TOLERANCE.
  • 2014 - 2017 Development of rAAV-mediated brain transduction with transient ultrasound-mediated modulation of the blood-brain interface in adult common marmoset toward modeling epilepsy
  • 2014 - 2017 Investigation of immune tolerance induction method for gene therapy of muscular dystrophy
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Papers (23):
  • Hiromi Hayashita-Kinoh, Posadas-Herrera Guillermo, Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Hironori Okada, Tomoko Chiyo, Shin'ichi Takeda, Takashi Okada. Improved transduction of canine X-linked muscular dystrophy with rAAV9-microdystrophin via multipotent MSC pretreatment. Molecular therapy. Methods & clinical development. 2021. 20. 133-141
  • Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Yuki Oda, Hiromi Hayashita-Kinoh, Shin'ichi Takeda, Takashi Okada. Enhanced cell survival and therapeutic benefits of IL-10-expressing multipotent mesenchymal stromal cells for muscular dystrophy. Stem cell research & therapy. 2021. 12. 1. 105-105
  • Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Posadas Herrera Guillermo, Hiromi Hayashita-Kinoh, Yasunobu Maruoka, Aki Nakamura-Takahasi, Koichi Kimura, Shin'ichi Takeda, Takashi Okada. Dental pulp stem cells can improve muscle dysfunction in animal models of Duchenne muscular dystrophy. Stem cell research & therapy. 2021. 12. 1. 78-78
  • Kazuhisa Takahashi, Tsutomu Igarashi, Koichi Miyake, Maika Kobayashi, Yuko Katakai, Hiromi Hayashita-Kinoh, Chiaki Fujimoto, Shuhei Kameya, Hiroshi Takahashi, Takashi Okada. Amount of Green Fluorescent Protein in the Anterior Chamber after Intravitreal Injection of Triple-Mutated Self-Complementary AAV2 Vectors is Not Affected by Previous Vitrectomy Surgery. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. 2021. 88. 2. 103-108
  • Akiko Ishii, Hironori Okada, Hiromi Hayashita-Kinoh, Jin-Hong Shin, Akira Tamaoka, Takashi Okada, Shin'ichi Takeda. rAAV8 and rAAV9-Mediated Long-Term Muscle Transduction with Tacrolimus (FK506) in Non-Human Primates. Molecular therapy. Methods & clinical development. 2020. 18. 44-49
more...
MISC (56):
  • Hiromi Hayashita-Kinoh, Posadas Herrera-Guillermo, Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Shin'ichi Takeda, Takashi Okada. Development of Administration Protocols for Reduction of the Necessary Dose of rAAV for Treatment. MOLECULAR THERAPY. 2022. 30. 4. 494-494
  • Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Hiromi Hayashita-Kinoh, Shin'ichi Takeda, Takashi Okada. Anti-Inflammatory Properties of IL-10-Expressing Multipotent Mesenchymal Stromal Cells for Duchenne Muscular Dystrophy. MOLECULAR THERAPY. 2022. 30. 4. 490-490
  • 喜納 裕美[早下], 岡田 尚巳. 【今知っておきたいゲノム医療と遺伝子治療-基礎から臨床まで】遺伝子治療 神経筋疾患 筋ジストロフィーの遺伝子治療. 小児内科. 2022. 54. 2. 329-332
  • Hiromi Hayashita-Kinoh, Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Shin'ichi Takeda, Takashi Okada. Improved Transduction of DMD Dog with rAAV-Microdystrophin via Multipotent Mesenchymal Cell Pretreatment. MOLECULAR THERAPY. 2021. 29. 4. 287-288
  • Hiromi Hayashita-Kinoh, Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Kazuhiro Takao, Tsutomu Igarashi, Shin'ichi Takeda, Takashi Okada. Development of Administration Protocols for Reduction of the Necessary Dose of rAAV for Treatment. MOLECULAR THERAPY. 2020. 28. 4. 327-327
more...
Patents (4):
Professional career (1):
  • 博士(医学) (東京大学)
Work history (5):
  • 2020/10 - 現在 The University of Tokyo The Institute of Medical Science
  • 2008/09 - 現在 National Center of Neurology and Psychiatry
  • 2014/09 - 2020/09 Nippon Medical School
  • 2007/03 - 2008/08 Hiroshima University
  • 2002/04 - 2007/02 Juntendo University
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