Art

J-GLOBAL ID：201502216348591226   Reference number：15A1309678

Degree of Maintenance of Lactate Dehydrogenase (LDH) Activity during Freeze/Thaw Process Highly Depends on Hydrophobic Chain Length of Synthetic Mono-Tailed Glycolipid Stabilizer

凍結/融解過程間の乳酸デヒドロゲナーゼ(LDH)活性の維持の程度は合成単尾糖脂質スタビライザの疎水鎖長に高度に依存する

Author (7)： OGAWA Shigesaburo (Kwansei Gakuin Univ., Hyogo, JPN) ,  OGAWA Shigesaburo (Keio Univ., Yokohama, JPN) ,  KAWAI Ryuichiro (Keio Univ., Yokohama, JPN) ,  KOGA Maito (Keio Univ., Yokohama, JPN) ,  ASAKURA Kouichi (Keio Univ., Yokohama, JPN) ,  TAKAHASHI Isao (Kwansei Gakuin Univ., Hyogo, JPN) ,  OSANAI Shuichi (Keio Univ., Yokohama, JPN)
Material： 低温生物工学会誌  (Cryobiology and Cryotechnology)
Volume： 61  Issue： 2  Page： 89-94  Publication year： Oct. 15, 2015 
JST Material Number： Z0889A  ISSN： 1340-7902  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： hare ,...
Semi thesaurus term： *cryoprotectant

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=15A1309678&from=J-GLOBAL&jstjournalNo=Z0889A") }}

JST classification (2)： Enzyme in general  (EB09010D) ,  Biological function  (EB05020M)

Substance index (4)： Octyl β-D-glucopyranoside ,  Hexyl β-D-glucopyranoside ,  6-O-Decanoyl-α-D-glucopyranosyl α-D-glucopyranoside ,  6-O-Octanoyl-α-D-glucopyranosyl α-D-glucopyranoside

Reference (20)：

• Strambini GB, Gabellieri E: Proteins in frozen solutions: evidence of ice-induced partial unfolding, Biophys J, 70, 971-976 (1996)
• Wang W: Lyophilization and development of solid protein pharmaceuticals, Int J Pharm, 203, 1-60 (2000)
• Carpenter JF, Izutsu KI, Randolph TW: Freezing- and drying-induced perturbations of protein structure and mechanisms of protein protection by stabilizing additives, In "Freeze drying/lyophilization of pharmaceutical and biological products, third edition", Rey L, May JC, eds, CRC Press, New York & London, Chapter 7, p167-197 (2010)
• Nema S, Avis KE: Freeze-thaw studies of a model protein, lactate dehydrogenase, in the presence of cryoprotectants, J Parenter Sci Technol, 47, 76-83 (1993)
• Anchordoquy TJ, Izutsu KI, Randolph TW, Carpenter JF: Maintenance of quaternary structure in the frozen state stabilizes lactate dehydrogenase during freeze-drying, Arch Biochem Biophys, 390, 35-41 (2001)

Terms in the title (11)： 凍結 ,  融解 ,  過程 ,  乳酸デヒドロゲナーゼ ,  LDH ,  活性 ,  程度 ,  尾 ,  糖脂質 ,  スタビライザ ,  鎖長