文献

J-GLOBAL ID：201502203709342124   整理番号：15A1263446

日本人メラノーマ患者におけるBRAF,NRASおよびKIT変異と関係した臨床的特徴

Clinical characteristics associated with BRAF, NRAS and KIT mutations in Japanese melanoma patients

著者 (16件)： SAKAIZAWA Kaori (Dep. of Dermatology, Shinshu Univ. School of Medicine, 3-1-1, Asahi, Matsumoto, Nagano 390-8621, JPN) ,  ASHIDA Atsuko (Dep. of Dermatology, Shinshu Univ. School of Medicine, 3-1-1, Asahi, Matsumoto, Nagano 390-8621, JPN) ,  UCHIYAMA Aya (Dep. of Dermatology, Shinshu Univ. School of Medicine, 3-1-1, Asahi, Matsumoto, Nagano 390-8621, JPN) ,  ITO Takamichi (Dep. of Dermatology, Graduate School of Medical Sciences, Kyushu Univ., 3-1-1, Maidashi, Higashi-ku, Fukuoka ...) ,  FUJISAWA Yasuhiro (Dep. of Dermatology, Univ. of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki 305-8575, JPN) ,  OGATA Dai (Dep. of Dermatology, Saitama Medical Univ., 38, Morohongo, Moroyama-machi, Iruma-gun, Saitama 350-0495, JPN) ,  MATSUSHITA Shigeto (Dep. of Dermato-Oncology/Dermatology, Kagoshima Medical Center, 8-1, Shiroyama-cho, Kagoshima 892-0853, JPN) ,  FUJII Kazuyasu (Dep. of Dermatology, Kagoshima Univ. Graduate School of Medical and Dental Sciences, 8-35-1, Sakuragaoka, Kagoshima ...) ,  FUKUSHIMA Satoshi (Dep. of Dermatology and Plastic Surgery, Fac. of Life Sciences, Kumamoto Univ., 1-1-1, Honjo, Kumamoto 860-0811, JPN) ,  SHIBAYAMA Yoshitsugu (Dep. of Dermatology, Fac. of Medicine, Fukuoka Univ., 7-45-1, Nanakuma, Jonan-ku, Fukuoka 814-0180, JPN) ,  HATTA Naohito (Dep. of Dermatology, Toyama Prefectural Central Hospital, 2-2-78, Nishinagae, Toyama 930-8550, JPN) ,  TAKENOUCHI Tatsuya (Dep. of Dermatology, Niigata Cancer Center Hospital, 2-15-3, Kawagishi-cho, Chuo-ku, Niigata 951-8566, JPN) ,  UEHARA Jiro (Dep. of Dermatology, Asahikawa Medical Univ., 1-1-1, Higashinijo, Midorigaoka, Asahikawa 078-8510, JPN) ,  OKUYAMA Ryuhei (Dep. of Dermatology, Shinshu Univ. School of Medicine, 3-1-1, Asahi, Matsumoto, Nagano 390-8621, JPN) ,  YAMAZAKI Naoya (Dep. of Dermatologic Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, JPN) ,  UHARA Hisashi (Dep. of Dermatology, Shinshu Univ. School of Medicine, 3-1-1, Asahi, Matsumoto, Nagano 390-8621, JPN)
資料名： Journal of Dermatological Science  (Journal of Dermatological Science)
巻： 80  号： 1  ページ： 33-37  発行年： 2015年10月 
JST資料番号： W1280A  ISSN： 0923-1811  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： メラノーマ細胞の治療に対する個々の感受性の遺伝的背景の重要性...

シソーラス用語： 黒色腫 ,...
準シソーラス用語： *遺伝子変異 ,...

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分類 (3件)： 腫ようの化学・生化学・病理学  (GE02030N) ,  皮膚の腫よう  (GF04000X) ,  分子遺伝学一般  (EC02010J)

引用文献 (21件)：

• H. Davies, G.R. Bignell, C. Cox, P. Stephens, S. Edkins, S. Clegg, et al., Mutations of the BRAF gene in human cancer, Nature 417 (2002) 949-954.
• P.B. Chapman, A. Hauschild, C. Robert, J.B. Haanen, P. Ascierto, J. Larkin, et al., Improved survival with vemurafenib in melanoma with BRAF V600E mutation, N. Engl. J. Med; 364 (2011) 2507-2516.
• K.T. Flaherty, J.R. Infante, A. Daud, R. Gonzalez, R.F. Kefford, J. Sosman, et al., Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations, N. Engl. J. Med. 367 (2012) 1694-1703.
• J.A. Curtin, J. Fridlyand, T. Kageshita, H.N. Patel, K.J. Busam, H. Kutzner, et al., Distinct sets of genetic alterations in melanoma, N. Engl. J. Med. 353 (2005) 2135-2147.
• J. Baüer, P. Buttner, R. Murali, I. Okamoto, N.A. Kolaitis, M.T. Landi, R.A. Scolyer, et al., BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site, Pigment Cell Melanoma Res. (2011) 345-351.

タイトルに関連する用語 (8件)： 日本人 ,  メラノーマ ,  患者 ,  BRAF ,  NRAS ,  KIT ,  変異 ,  臨床