文献

J-GLOBAL ID：201002200257086706   整理番号：10A0188473

リポソーム気泡と腫瘍の超音波照射を用いたIL-12遺伝子送達による癌遺伝子療法

Cancer gene therapy by IL-12 gene delivery using liposomal bubbles and tumoral ultrasound exposure

著者 (12件)： SUZUKI Ryo (Dep. of Biopharmaceutics, School of Pharmaceutical Sciences, Teikyo Univ., Sagamihara, Kanagawa, JPN) ,  NAMAI Eisuke (Dep. of Biopharmaceutics, School of Pharmaceutical Sciences, Teikyo Univ., Sagamihara, Kanagawa, JPN) ,  ODA Yusuke (Dep. of Biopharmaceutics, School of Pharmaceutical Sciences, Teikyo Univ., Sagamihara, Kanagawa, JPN) ,  NISHIIE Norihito (Dep. of Biopharmaceutics, School of Pharmaceutical Sciences, Teikyo Univ., Sagamihara, Kanagawa, JPN) ,  OTAKE Shota (Dep. of Biopharmaceutics, School of Pharmaceutical Sciences, Teikyo Univ., Sagamihara, Kanagawa, JPN) ,  KOSHIMA Risa (Dep. of Biopharmaceutics, School of Pharmaceutical Sciences, Teikyo Univ., Sagamihara, Kanagawa, JPN) ,  HIRATA Keiichi (Dep. of Biopharmaceutics, School of Pharmaceutical Sciences, Teikyo Univ., Sagamihara, Kanagawa, JPN) ,  TAIRA Yuichiro (Dep. of Biopharmaceutics, School of Pharmaceutical Sciences, Teikyo Univ., Sagamihara, Kanagawa, JPN) ,  UTOGUCHI Naoki (Dep. of Biopharmaceutics, School of Pharmaceutical Sciences, Teikyo Univ., Sagamihara, Kanagawa, JPN) ,  NEGISHI Yoichi (Dep. of Drug and Gene Delivery System, School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sci., Hachioji, Tokyo, JPN) ,  NAKAGAWA Shinsaku (Dep. of Biotechnology and Therapeutics, Graduate School of Pharmaceutical Sciences, Osaka Univ., Suita, Osaka, JPN) ,  MARUYAMA Kazuo (Dep. of Biopharmaceutics, School of Pharmaceutical Sciences, Teikyo Univ., Sagamihara, Kanagawa, JPN)
資料名： Journal of Controlled Release  (Journal of Controlled Release)
巻： 142  号： 2  ページ： 245-250  発行年： 2010年03月03日 
JST資料番号： C0308D  ISSN： 0168-3659  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： インターロイキン-12(IL-12)遺伝子治療は癌細胞の免疫...

シソーラス用語： *インターロイキン ,...
準シソーラス用語： Tリンパ球 ,...

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分類 (3件)： 生物薬剤学(基礎)  (GY01021U) ,  腫ようの実験的治療  (GE02040Y) ,  分子遺伝学一般  (EC02010J)

物質索引 (1件)： ペルフルオロプロパン

引用文献 (34件)：

• U. Gubler, A.O. Chua, D.S. Schoenhaut, C.M. Dwyer, W. McComas, R. Motyka, N. Nabavi, A.G. Wolitzky, P.M. Quinn, P.C. Familletti, Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor, Proc Natl Acad Sci U S A 88 (1991) 4143-4147.
• S.F. Wolf, P.A. Temple, M. Kobayashi, D. Young, M. Dicig, L. Lowe, R. Dzialo, L. Fitz, C. Ferenz, R.M. Hewick, Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells, J Immunol 146 (1991) 3074-3081.
• M.J. Brunda, Interleukin-12, J Leukoc Biol 55 (1994) 280-288.
• C.L. Nastala, H.D. Edington, T.G. McKinney, H. Tahara, M.A. Nalesnik, M.J. Brunda, M.K. Gately, S.F. Wolf, R.D. Schreiber, W.J. Storkus, Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production, J Immunol 153 (1994) 1697-1706.
• W.G. Yu, M. Ogawa, J. Mu, K. Umehara, T. Tsujimura, H. Fujiwara, T. Hamaoka, IL-12-induced tumor regression correlates with in situ activity of IFN-gamma produced by tumor-infiltrating cells and its secondary induction of anti-tumor pathways, J Leukoc Biol 62 (1997) 450-457.

タイトルに関連する用語 (7件)： リポソーム ,  気泡 ,  腫瘍 ,  超音波照射 ,  IL-12 ,  遺伝子送達 ,  癌遺伝子療法