文献

J-GLOBAL ID：201102285373348974   整理番号：11A1769464

日本の肺癌症例における癌リスクと薬物代謝酵素遺伝子(CYP2A6,CYP2A13,CYP4B1,SULT1A1,GSTM1およびGSTT1)多型の間の関連性

Association between Cancer Risk and Drug-metabolizing Enzyme Gene (CYP2A6, CYP2A13, CYP4B1, SULT1A1, GSTM1, and GSTT1) Polymorphisms in Cases of Lung Cancer in Japan

著者 (11件)： TAMAKI Yuichiro (Lab. of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku Univ.) ,  ARAI Tomio (Dep. of Pathology, Tokyo Metropolitan Geriatric Hospital and Inst. of Gerontology) ,  SUGIMURA Haruhiko (First Dep. of Pathology, Hamamatsu Univ. School of Medicine) ,  SASAKI Takamitsu (Dep. of Environmental and Health Sci., Tohoku Pharmaceutical Univ.) ,  HONDA Masashi (Lab. of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku Univ.) ,  MUROI Yuka (Lab. of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku Univ.) ,  MATSUBARA Yoichi (Dep. of Medical Genetics, Tohoku Univ. School of Medicine) ,  KANNO Shuichi (Dep. of Clinical Pharmacotherapeutics, Tohoku Pharmaceutical Univ.) ,  ISHIKAWA Masaaki (Dep. of Clinical Pharmacotherapeutics, Tohoku Pharmaceutical Univ.) ,  HIRASAWA Noriyasu (Lab. of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku Univ.) ,  HIRATSUKA Masahiro (Lab. of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku Univ.)
資料名： Drug Metabolism and Pharmacokinetics  (Drug Metabolism and Pharmacokinetics)
巻： 26  号： 5  ページ： 516-522 (J-STAGE)  発行年： 2011年 
JST資料番号： X0758A  ISSN： 1347-4367  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 発癌物質の代謝に関与する酵素の遺伝子多型は肺癌への個々の感受...

シソーラス用語： ヒト ,...
準シソーラス用語： CYP2A13 ,...

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分類 (2件)： 呼吸器の腫よう  (GI04000G) ,  発癌機序・因子  (GE02020C)

引用文献 (28件)：

• 1) Greenlee, R. T., Murray, T., Bolden, S. and Wingo, P. A.: Cancer statistics, 2000. CA Cancer J. Clin., 50: 7–33 (2000).
• 2) Petrauskaitė, R., Pershagen, G. and Gurevicius, R.: Lung cancer near an industrial site in Lithuania with major emissions of airway irritants. Int. J. Cancer, 99: 106–111 (2002).
• 3) Stellman, S. D., Takezaki, T., Wang, L., Chen, Y., Citron, M. L., Djordjevic, M. V., Harlap, S., Muscat, J. E., Neugut, A. I., Wynder, E. L., Ogawa, H., Tajima, K. and Aoki, K.: Smoking and lung cancer risk in American and Japanese men: an international case-control study. Cancer Epidemiol. Biomarkers Prev., 10: 1193–1199 (2001).
• 4) Bao, Z., He, X. Y., Ding, X., Prabhu, S. and Hong, J. Y.: Metabolism of nicotine and cotinine by human cytochrome P450 2A13. Drug Metab. Dispos., 33: 258–261 (2005).
• 5) Su, T., Bao, Z., Zhang, Q. Y., Smith, T. J., Hong, J. Y. and Ding, X.: Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res., 60: 5074–5079 (2000).

タイトルに関連する用語 (13件)： 日本 ,  肺癌 ,  症例 ,  癌 ,  リスク ,  薬物代謝 ,  酵素遺伝子 ,  CYP2A6 ,  CYP4B1 ,  GSTM1 ,  GSTT1 ,  多型 ,  関連性