文献

J-GLOBAL ID：201702247883513879   整理番号：17A0183231

AhRシグナリングの過剰な活性化は,発達中のマウス海馬のCA1領域でニューロン移動を破壊する

Excessive activation of AhR signaling disrupts neuronal migration in the hippocampal CA1 region in the developing mouse

著者 (10件)： Kimura Eiki (Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo) ,  Kimura Eiki (Environmental Biology Laboratory, Faculty of Medicine, University of Tsukuba) ,  Kubo Ken-ichiro (Department of Anatomy, Keio University School of Medicine) ,  Endo Toshihiro (Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo) ,  Endo Toshihiro (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo) ,  Nakajima Kazunori (Department of Anatomy, Keio University School of Medicine) ,  Kakeyama Masaki (Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo) ,  Kakeyama Masaki (Laboratory for Systems Neuroscience and Preventive Medicine, Faculty of Human Sciences, Waseda University) ,  Tohyama Chiharu (Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo) ,  Tohyama Chiharu (Environmental Biology Laboratory, Faculty of Medicine, University of Tsukuba)
資料名： Journal of Toxicological Sciences  (Journal of Toxicological Sciences)
巻： 42  号： 1  ページ： 25-30(J-STAGE)  発行年： 2017年 
JST資料番号： Z0265B  ISSN： 0388-1350  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： アリール炭化水素受容体(AhR)は,普遍的な環境汚染物質であ...

シソーラス用語： *Ah受容体 ,...
準シソーラス用語： 細胞シグナリング ,...

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著者キーワード (5件)： Aryl hydrocarbon receptor ,  Developmental neurotoxicity ,  Hippocampus ,  In utero electroporation ,  Neuronal migration

分類 (3件)： 神経の基礎医学  (GN01020W) ,  細胞膜の受容体  (EF04030C) ,  婦人科・産科の基礎医学  (GS01020L)

引用文献 (29件)：

• Andersson, P., McGuire, J., Rubio, C., Gradin, K., Whitelaw, M.L., Pettersson, S., Hanberg, A. and Poellinger, L. (2002): A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors. Proc. Natl. Acad. Sci. USA, 99, 9990-9995.
• Basu, J. and Siegelbaum, S.A. (2015): The Corticohippocampal Circuit, Synaptic Plasticity, and Memory. Cold Spring Harb Perspect. Biol., 7.
• Brunnberg, S., Andersson, P., Lindstam, M., Paulson, I., Poellinger, L. and Hanberg, A. (2006): The constitutively active Ah receptor (CA-Ahr) mouse as a potential model for dioxin exposure--effects in vital organs. Toxicology, 224, 191-201.
• Collins, L.L., Williamson, M.A., Thompson, B.D., Dever, D.P., Gasiewicz, T.A. and Opanashuk, L.A. (2008): 2,3,7,8-Tetracholorodibenzo-p-dioxin exposure disrupts granule neuron precursor maturation in the developing mouse cerebellum. Toxicol. Sci., 103, 125-136.
• Dever, D.P., Adham, Z.O., Thompson, B., Genestine, M., Cherry, J., Olschowka, J.A., DiCicco-Bloom, E. and Opanashuk, L.A. (2016): Aryl hydrocarbon receptor deletion in cerebellar granule neuron precursors impairs neurogenesis. Dev. Neurobiol., 76, 533-550.

タイトルに関連する用語 (9件)： AhR ,  シグナリング ,  活性化 ,  発達 ,  マウス ,  海馬 ,  CA1領域 ,  ニューロン移動 ,  破壊