文献

J-GLOBAL ID：201702279869220606   整理番号：17A0488190

セツキシマブは,結腸直腸癌における肝転移部位への免疫細胞浸潤を強く増加させる

Cetuximab strongly enhances immune cell infiltration into liver metastatic sites in colorectal cancer

著者 (17件)： Inoue Yuka (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Hazama Shoichi (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Hazama Shoichi (Department of Translational Research and Developmental Therapeutics against Cancer, Yamaguchi University School of Medicine, Ube, Yamaguchi, Japan) ,  Suzuki Nobuaki (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Tokumitsu Yukio (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Tokumitsu Yukio (Department of Translational Research and Developmental Therapeutics against Cancer, Yamaguchi University School of Medicine, Ube, Yamaguchi, Japan) ,  Kanekiyo Shinsuke (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Tomochika Shinobu (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Tsunedomi Ryouichi (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Tokuhisa Yoshihiro (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Iida Michihisa (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Sakamoto Kazuhiko (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Takeda Shigeru (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Ueno Tomio (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Yoshino Shigefumi (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Yoshino Shigefumi (Oncology Center, Yamaguchi University Hospital, Ube, Yamaguchi, Japan) ,  Nagano Hiroaki (Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan)
資料名： Cancer Science (Web)  (Cancer Science (Web))
巻： 108  号： 3  ページ： 455-460  発行年： 2017年 
JST資料番号： U0505A  ISSN： 1349-7006  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： セツキシマブは結腸直腸癌に対し活性を示す。最近の研究は,セツ...

シソーラス用語： *結腸腫瘍 ,...
準シソーラス用語： *結腸直腸癌 ,...

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著者キーワード (5件)： Antibody-dependent cellular cytotoxicity ,  cetuximab ,  colorectal cancer ,  immune-enhancing effect ,  TILs

分類 (4件)： 腫ようの化学・生化学・病理学  (GE02030N) ,  消化器の腫よう  (GH04000D) ,  抗腫よう薬の臨床への応用  (GW16020L) ,  腫よう免疫  (ED03040A)

引用文献 (45件)：

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• Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127: 2893-917.
• de Gramont A, Figer A, Seymour M et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000; 18: 2938-47.
• Saltz LB, Clarke S, Diaz-Rubio E et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008; 26: 2013-9.
• Tournigand C, Andre T, Achille E et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004; 22: 229-37.

タイトルに関連する用語 (5件)： セツキシマブ ,  結腸直腸癌 ,  肝転移 ,  免疫細胞 ,  浸潤