文献

J-GLOBAL ID：201702290204013440   整理番号：17A0872393

進行型固形腫瘍の患者における次世代シークエンシングベースマルチプレックス遺伝子アッセイを用いる臨床的シークエンシング

Clinical sequencing using a next-generation sequencing-based multiplex gene assay in patients with advanced solid tumors

著者 (19件)： Kou Tadayuki (Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Kanai Masashi (Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Yamamoto Yoshihiro (Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Kamada Mayumi (Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Nakatsui Masahiko (Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Sakuma Tomohiro (Biomedical Department, Mitsui Knowledge Industry Co., Ltd., Tokyo, Japan) ,  Mochizuki Hiroaki (Biomedical Department, Mitsui Knowledge Industry Co., Ltd., Tokyo, Japan) ,  Hiroshima Akinori (Biomedical Department, Mitsui Knowledge Industry Co., Ltd., Tokyo, Japan) ,  Sugiyama Aiko (DSK Project, Medical Innovation Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Nakamura Eijiro (DSK Project, Medical Innovation Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Miyake Hidehiko (Clinical Genetics Unit, Kyoto University Hospital, Kyoto, Japan) ,  Minamiguchi Sachiko (Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan) ,  Takaori Kyoichi (Division of Hepatobiliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Matsumoto Shigemi (Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Haga Hironori (Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan) ,  Seno Hiroshi (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Kosugi Shinji (Department of Medical Ethics and Medical Genetics, Kyoto University School of Public Health, Kyoto, Japan) ,  Okuno Yasushi (Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Muto Manabu (Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan)
資料名： Cancer Science (Web)  (Cancer Science (Web))
巻： 108  号： 7  ページ： 1440-1446  発行年： 2017年 
JST資料番号： U0505A  ISSN： 1349-7006  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： 次世代シークエンシング(NGS)技術の進歩により,医師が日常...

シソーラス用語： ヒト ,...
準シソーラス用語： 遺伝子変異

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著者キーワード (5件)： Actionable mutation ,  genotype-directed therapy ,  multiplex gene assay ,  next-generation sequencing ,  precision cancer medicine

分類 (1件)： 腫ようの診断  (GE03020J)

引用文献 (44件)：

• Jameson JL, Longo DL. Precision medicine-personalized, problematic, and promising. N Engl J Med 2015; 372: 2229-34.
• Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-39.
• Douillard JY, Oliner KS, Siena S et al. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med 2013; 369: 1023-34.
• Von Hoff DD, Stephenson JJ Jr, Rosen P et al. Pilot study using molecular profiling of patients’ tumors to find potential targets and select treatments for their refractory cancers. J Clin Oncol 2010; 28: 4877-83.
• Frampton GM, Fichtenholtz A, Otto GA et al. Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nat Biotechnol 2013; 31: 1023-31.

タイトルに関連する用語 (8件)： 固形腫瘍 ,  患者 ,  次世代シークエンシング ,  マルチプレックス ,  遺伝子 ,  アッセイ ,  臨床 ,  シークエンシング