文献

J-GLOBAL ID：201802215748793364   整理番号：18A0253705

Mutyh欠失マウスにおけるFenton反応誘発腎発癌はラットモデルより少ない染色体異常を示す

Fenton reaction-induced renal carcinogenesis in Mutyh-deficient mice exhibits less chromosomal aberrations than the rat model

著者 (13件)： Li Guang Hua (Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Akatsuka Shinya (Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Chew Shan Hwu (Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Jiang Li (Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Nishiyama Takahiro (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Sakamoto Akihiko (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Takahashi Takashi (Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Futakuchi Mitsuru (Department of Molecular Toxicology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan) ,  Suzuki Hiromu (Department of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan) ,  Sakumi Kunihiko (Division of Neurofunctional Genomics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan) ,  Nakabeppu Yusaku (Division of Neurofunctional Genomics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan) ,  Toyokuni Shinya (Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Toyokuni Shinya (Sydney Medical School, The University of Sydney, NSW, Australia)
資料名： Pathology International  (Pathology International)
巻： 67  号： 11  ページ： 564-574  発行年： 2017年11月 
JST資料番号： W0853A  ISSN： 1320-5463  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オーストラリア (AUS)  言語： 英語 (EN)

抄録/ポイント： 鉄過剰を含む酸化ストレスは発癌と関係づけられている。DNAに...

シソーラス用語： *遺伝子欠損 ,...
準シソーラス用語： *Fenton反応誘発腎発癌 ,...

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著者キーワード (5件)： Fe-NTA ,  リンパ腫 ,  Mutyh欠失マウス ,  酸化ストレス ,  腎細胞癌

分類 (2件)： 発癌機序・因子  (GE02020C) ,  泌尿生殖器の腫よう  (GM04000S)

物質索引 (1件)： ニトリロ三酢酸

引用文献 (42件)：

• Hussain SP, Hofseth LJ, Harris CC. Radical causes of cancer. Nat Rev Cancer 2003; 3: 276-85.
• Toyokuni S. Oxidative stress as an iceberg in carcinogenesis and cancer biology. Arch Biochem Biophys 2016; 595: 46-9.
• Toyokuni S. Iron-induced carcinogenesis: The role of redox regulation. Free Radic Biol Med 1996; 20: 553-66.
• Toyokuni S. Role of iron in carcinogenesis: Cancer as a ferrotoxic disease. Cancer Sci 2009; 100: 9-16.
• Toyokuni S, Ito F, Yamashita K, Okazaki Y, Akatsuka S. Iron and thiol redox signaling in cancer: An exquisite balance to escape ferroptosis. Free Radic Biol Med 2017; 108: 610-26.

タイトルに関連する用語 (10件)： MUTYH ,  欠失 ,  マウス ,  Fenton反応 ,  誘発 ,  腎 ,  発癌 ,  ラット ,  モデル ,  染色体異常