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J-GLOBAL ID：202002245587255991   整理番号：20A0292649

若い成人における毛髪中の鉄レベルと脳構造および機能との関連【JST・京大機械翻訳】

Association of iron levels in hair with brain structures and functions in young adults

著者 (27件)： Takeuchi Hikaru (Division of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Taki Yasuyuki (Division of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Taki Yasuyuki (Division of Medical Neuroimaging Analysis, Department of Community Medical Supports, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan) ,  Taki Yasuyuki (Department of Radiology and Nuclear Medicine, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Nouchi Rui (Creative Interdisciplinary Research Division, Frontier Research Institute for Interdisciplinary Science, Tohoku University, Sendai, Japan) ,  Nouchi Rui (Human and Social Response Research Division, International Research Institute of Disaster Science, Tohoku University, Sendai, Japan) ,  Nouchi Rui (Department of Advanced Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Yokoyama Ryoichi (School of Medicine, Kobe University, Kobe, Japan) ,  Kotozaki Yuka (Division of Clinical research, Medical-Industry Translational Research Center, Fukushima Medical University School of Medicine, Fukushima, Japan) ,  Nakagawa Seishu (Department of Human Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Nakagawa Seishu (Division of Psychiatry, Tohoku Medical and Pharmaceutical University, Sendai, Japan) ,  Sekiguchi Atsushi (Division of Medical Neuroimaging Analysis, Department of Community Medical Supports, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan) ,  Sekiguchi Atsushi (Department of Behavioral Medicine, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan) ,  Iizuka Kunio (Department of Psychiatry, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Yamamoto Yuki (Department of Human Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Hanawa Sugiko (Department of Human Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Araki Tsuyoshi (ADVANTAGE Risk Management Co., Ltd., Japan) ,  Miyauchi Carlos Makoto (Department of Language Sciences, Graduate School of Humanities, Tokyo Metropolitan University, Tokyo, Japan) ,  Sakaki Kohei (Department of Advanced Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Nozawa Takayuki (Research Center for the Earth Inclusive Sensing Empathizing with Silent Voices, Tokyo Institute of Technology, Tokyo, Japan) ,  Ikeda Shigeyuki (Department of Ubiquitous Sensing, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Yokota Susumu (Division of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Daniele Magistro (Department of Sport Science, School of Science and Technology, Nottingham Trent University, Clifton, Nottingham, United Kingdom) ,  Sassa Yuko (Division of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Kawashima Ryuta (Division of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Kawashima Ryuta (Department of Advanced Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Kawashima Ryuta (Department of Human Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan)
資料名： Journal of Trace Elements in Medicine and Biology  (Journal of Trace Elements in Medicine and Biology)
巻： 58  ページ： Null  発行年： 2020年 
JST資料番号： T0779A  ISSN： 0946-672X  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 鉄は正常な脳機能と発達において重要な役割を果たすが,それは神経学的効果が悪いことも知られている。ここでは,590人の健康な若年成人の研究コホートにおける局所的灰白質容積(rGMV),局所脳血流量(rCBF),分数異方性(FA),平均拡散率(MD)および認知差と毛髪中の鉄レベルの関係を検討した。著者らの知見は,高い鉄レベルが海馬を含む領域における低いrGMV,脳の前部と後部におけるより低いrCBF,脳梁の脾臓を含む領域におけるより大きなFA,左海馬におけるより大きなMDと前頭葉を含む領域に関連することを示した。これらの結果は,鉄が健常若年成人における神経機構において多様な役割を果たすという概念と互換性がある。Copyright 2020 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 異方性 ,  脳梁 ,  *鉄 ,  鉱物 ,  母集団 ,  海馬 ,  互換性 ,  灰白質 ,  潅流 ,  前頭葉 ,  脾臓
準シソーラス用語： 神経機構 ,  若年成人 ,  脳機能 ,  *脳構造 , 【Automatic Indexing@JST】

著者キーワード (6件)： 毛髪鉱物 ,  鉄 ,  地域灰白質容積 ,  Hippocampus ,  拡散テンソル画像 ,  潅流

分類 (2件)： 代謝異常・栄養性疾患一般  (GD05010J) ,  動物の代謝と栄養一般  (EJ02031R)

タイトルに関連する用語 (4件)： 成人 ,  毛髪 ,  鉄 ,  脳構造