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J-GLOBAL ID：202002253262380719   整理番号：20A1163149

MDR1ノックアウトヒト人工多能性幹細胞株の確立

Establishment of MDR1-knockout human induced pluripotent stem cell line

著者 (14件)： Negoro Ryosuke (Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Kawai Kanae (Laboratory of Biochemistry and Molecular Biology, School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Ichikawa Moe (Laboratory of Biochemistry and Molecular Biology, School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Deguchi Sayaka (Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Deguchi Sayaka (Laboratory of Hepatocyte Regulation, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan) ,  Takayama Kazuo (Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Takayama Kazuo (Laboratory of Biochemistry and Molecular Biology, School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Takayama Kazuo (Laboratory of Hepatocyte Regulation, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan) ,  Takayama Kazuo (PRESTO, Japan Science and Technology Agency, Saitama, 332-0012, Japan) ,  Mizuguchi Hiroyuki (Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Mizuguchi Hiroyuki (Laboratory of Biochemistry and Molecular Biology, School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Mizuguchi Hiroyuki (Laboratory of Hepatocyte Regulation, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan) ,  Mizuguchi Hiroyuki (Global Center for Medical Engineering and Informatics, Osaka University, Osaka, 565-0871, Japan) ,  Mizuguchi Hiroyuki (Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, Osaka, 565-0871, Japan)
資料名： Drug Metabolism and Pharmacokinetics (Web)  (Drug Metabolism and Pharmacokinetics (Web))
巻： 35  号： 3  ページ： 288-296  発行年： 2020年 
JST資料番号： U0705A  ISSN： 1347-4367  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 多剤耐性1(MDR1)は,肝臓,小腸および血液脳関門(BBB...

シソーラス用語： *iPS細胞 ,...
準シソーラス用語： 腸細胞 ,...

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著者キーワード (8件)： iPS細胞 ,  ABCB1 ,  MDR1 ,  P-GP ,  CRISPR-Cas9 ,  トランスポーター ,  ゲノム編集 ,  肝細胞

分類 (2件)： 生物薬剤学(基礎)  (GY01021U) ,  細胞学一般  (EF01000A)

タイトルに関連する用語 (5件)： MDR1 ,  ノックアウト ,  ヒト ,  人工多能性幹細胞 ,  株