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J-GLOBAL ID：200901006408458524 Update date: Jul. 17, 2024

Shibuya Masatoshi

Shibuya Masatoshi

Affiliation and department：
Job title： Associate Professor

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (1)： Organic Synthesis

Research theme for competitive and other funds (16)：

2019 - 2022 Development of polysubstituted heterocycles using boron catalysts
2016 - 2019 Development of new strategy for electrophilic acitivation of C-C multiple bonds
2014 - 2016 新規有機ニトロキシラジカル型酸化触媒の開発と神経栄養因子様活性天然物の合成
2011 - 2015 Development of a novel selective oxidation of alcohols based on the design of a nitroxy radical catalyst
2009 - 2011 Development of oxoammonium-salt-type catalysts for highly enantioselective oxidation of alcohols

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Papers (50)：

Masatoshi Shibuya, Miki Matsuda, Yoshihiko Yamamoto. 1,2-Carbopentafluorophenylation of Alkynes: The Metallomimetic Pull-Push Reactivity of Tris(pentafluorophenyl)borane. Chemistry - A European Journal. 2021. 27. 34. 8822-8831
Haruki Inada, Masatoshi Shibuya, Yoshihiko Yamamoto. Synthesis of Unprotected 2-Arylglycines by Transamination of Arylglyoxylic Acids with 2-(2-Chlorophenyl)glycine. Journal of Organic Chemistry. 2020. 85. 17. 11047-11059
Masatoshi Shibuya. Nitroxyl radical-catalyzed chemoselective alcohol oxidation for the synthesis of polyfunctional molecules. Tetrahedron Letters. 2020. 61. 8. 151515-151515
Tomoyoshi Kawamura, Hirokazu Moriya, Masatoshi Shibuya, Yoshihiko Yamamoto. Diastereoselective Methylation at the Congested β-Position of a Butenolide Ring: Studies toward the Synthesis of seco-Prezizaane-Type Sesquiterpenes. The Journal of Organic Chemistry. 2019. 84. 19. 12508-12519
Masatoshi Shibuya, Shohei Kawano, Shoji Fujita, Yoshihiko Yamamoto. Boron-Catalyzed Hydroamination/Hydroallylation and Hydroamination/Hydrocyanation of Unactivated Alkynes. Asian Journal of Organic Chemistry. 2019. 8. 7. 1075-1079

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MISC (94)：

Naomi Tsuburaya, Kengo Homma, Tsunehiko Higuchi, Andrii Balia, Hiroyuki Yamakoshi, Norio Shibata, Seiichi Nakamura, Hidehiko Nakagawa, Shin-ichi Ikeda, Naoki Umezawa, et al. A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model. NATURE COMMUNICATIONS. 2018. 9. 1. 2668
Masatoshi Shibuya, Masaki Okamoto, Shoji Fujita, Masanori Abe, Yoshihiko Yamamoto. Boron-Catalyzed Double Hydrofunctionalization Reactions of Unactivated Alkynes. ACS Catalysis. 2018. 8. 5. 4189-4193
Hibi, Takahide, Ohtsuka, Hokuto, Shimasaki, Takafumi, Inui, Shougo, Shibuya, Masatoshi, Tatsukawa, Hideki, Kanie, Kei, Yamamoto, Yoshihiko, Aiba, Hirofumi. Tschimganine and its derivatives extend the chronological life span of yeast via activation of the Sty1 pathway. Genes to Cells. 2018. 23. 8. 620-637
Masatoshi Shibuya, Shoji Fujita, Yoshihiko Yamamoto. Intramolecular Hydroalkoxylation/Reduction and Hydroamination/Reduction of Unactivated Alkynes Using a Silane-Iodine Catalytic System. Synthesis. 2017. 49. 18. 4199-4204
Yoshihiko Yamamoto, Yuta Okude, Shota Mori, Masatoshi Shibuya. Combined Experimental and Computational Study on Ruthenium(II)-Catalyzed Reactions of Diynes with Aldehydes and N,N-Dimethylformamide. The Journal of Organic Chemistry. 2017. 82. 15. 7964-7973

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Patents (2)：

トリフルオロメチル置換セミスクアレートの製造方法,トリフルオロメチル置換セミスクアレートを起点とするトリフルオロメチル化合物の製造方法及びトリフルオロメチル基含有化合物
α-ヒドロキシカルボン酸の製造方法

Education (2)：

2002 - 2002 Tohoku University Graduate School, Division of Pharmaceutical Sciences
1998 - 2002 Tohoku University Faculty of Pharmaceutical Science

Professional career (1)：

博士(薬学) (東北大学)

Work history (5)：

2023/04 - 現在 Japan Women's University Faculty of Science Department of Chemical and Biological Sciences Associate Professor
2022/07 - 2023/03 Nagoya University, Graduate School of Pharmaceutical Sciences Associate Professor
2012/04 - 2022/06 Nagoya University Graduate School of Pharmaceutical Sciences Department of Basic Medicinal Sciences Organic Chemistry Lecturer
2009/03/01 - 2012/03/31 assistant professor
2002/10/01 - 2009/02/28 助手

Association Membership(s) (5)：

日本プロセス化学会 , 有機合成化学協会 , 日本薬学会 , 日本化学会 , American Chemical Society

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