Mizuno Kouichi

ミズノコウイチ | Mizuno Kouichi

Affiliation and department：
Homepage URL (1)： http://www.akita-pu.ac.jp/bioresource/DBT/Plantmetfunc/mizuno/index.html

Research field (2)： Plants: molecular biology and physiology , Applied biochemistry

Research keywords (3)：植物代謝化学 , 酵素化学 , 二次代謝

Research theme for competitive and other funds (8)：

2008 - 2010 Molecular biological analysis of relationship between caffeine synthetic ability and entomophily in Citrus species.
2003 - 2004 コーヒー含有二次代謝産物(ポリフェノール類)の生合成機構の解明
2001 - 2002 コーヒーカフェイン生合成の分子機構の解明
2000 - 2002 重金属汚染土壌の浄化を目指した植物体の創出の基礎的研究
1998 - 2001 Functional alteration of cereal starches using the genes encoding starch-synthesizing enzymes

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Papers (43)：

Manami Oyama, Tetsuo Tokiwano, Hiromi Ota, Kouichi Mizuno, Keimei Oh, Satoru Kawaii, Yuko Yoshizawa. β-Sitosterol Oxides From the Dried Stem of Salix gilgiana Inhibit the Proliferation of HL-60 Leukemic Cells. Current Bioactive Compounds. 2020. 16. 3. 329-334
Oyama M, Tokiwano T, Ota H, Mizuno K, Oh K, Kawaii S, Yoshizawa Y. Beta-sitosterol oxides from the dried stem of Salix gilgiana as antiproliferative compounds to HL-60 leukemic cells. Current Bioactive Compounds. 2018. 14. DOI: 10.2174/15734072146661810
Manami Oyama, Tetsuo Tokiwano, Satoru Kawaii, Yasunori Yoshida, Kouichi Mizuno, Keimei Oh, Yuko Yoshizawa. Protodioscin, isolated from the rhizome of dioscorea tokoro collected in northern Japan is the major antiproliferative compound to HL-60 leukemic cells. Current Bioactive Compounds. 2017. 13. 2. 170-174
Kouichi Mizuno, Tetsuo Tokiwano, Yuko Yoshizawa. Gene expression analysis of enzymes of the carotenoid biosynthesis pathway involved in beta-cryptoxanthin accumulation in wild raspberry, Rubus palmatus. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017. 484. 4. 845-849
Ashihara H, Mizuno K, Yokota T, Crozier A. Xanthine Alkaloids: Occurrence, Biosynthesis, and Function in Plants. Progress in the chemistry of organic natural products. 2017. 105. 1-88

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MISC (22)：

Mariko Ishida, Chikako Kakuta, Kouichi Mizuno, Misako Kato. Structure and function of caffeine synthase homologous genes from Camellia japonica. PLANT AND CELL PHYSIOLOGY. 2007. 48. S223-S223
A Takashi, U Chie, L Ben Mohamed, K Mizuno, T Fujimura. Isolation and characterization of genes induced by ABA and sucrose synergistically in the rice callus. PLANT AND CELL PHYSIOLOGY. 2004. 45. 0. S94-S94
水野幸一, 藤村達人. 重金属汚染耕地のファイトレメディエーション (日本作物学会・日本育種学会合同シンポジウム). 農業および園芸. 2003. 78. 3. 365-369
N Yoneyama, K Mizuno, Y Tomoda, H Ashihara, M Kato. Isolation and functional analysis of caffeine synthase homologous gene in purine alkaloids biosynthetic plants. PLANT AND CELL PHYSIOLOGY. 2003. 44. S194-S194
T Akihiro, K Mizuno, T Fujimura. Search for key enzymes of starch biosynthetic enzymes in rice callus. PLANT AND CELL PHYSIOLOGY. 2003. 44. 0. S31-S31

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Patents (11)：

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Lectures and oral presentations (16)：

Isolation and characterization of linalool UDP-Glc glycosyltransferases from Coffea arabica
(28th International scientific colloquium 2021 on coffee, ASIC, Montpellier, France 2021)
Functional characterization of caffeine synthase genes from wild coffee, and discussion of those molecular evolutions
(28th International scientific colloquium 2021 on coffee, ASIC, Montpellier, France 2021)
学生自主研究制度〜学生の好奇心に応える教育プログラム〜
(第5回大学コンソーシアムあきた高等教育セミナー 2019)
Biochemistry and molecular biology in caffeine biosynthesis. Characterization of caffeine synthase family in coffee.
(The 4th Solanaceae Genome Workshop 2007 2007)
カフェイン生合成関連N-メチルトランスフェラーゼの分子進化
(日本農芸化学会東北支部シンポジウム 2007)

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Education (1)：

1991 - 1996 University of Tsukuba

Professional career (2)：

博士(農学) (筑波大学)
修士(農学) (筑波大学)

Work history (10)：

2024/04 - 現在 Akita Prefectural University
2020/04 - 現在 Akita Prefectural University Faculty of Bioresource Sciences Professor
2005/04 - 2020/03 Akita Prefectural University Faculty of Bioresource Sciences
2016/06 - 2017/01 IRD-Montpellier DIADE 特別教授
2002/05 - 2005/03 Akita Prefectural University Faculty of Bioresource Sciences

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Committee career (6)：

2024/04 - 現在日本農芸化学会代議員
2022/04 - 現在東北植物学会県連絡幹事(秋田県)
2020/04 - 現在日本農芸化学会東北支部代表参与
2023/07 - 2024/06 日本学術振興会特別研究員等審査会専門委員、卓越研究員候補者選考委員会書面審査員及び国際事業委員会書面審査員・書面評価員
2015/05 - 2016/06 日本農芸化学会東北支部庶務幹事

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Awards (3)：

2020/03 - (公)日本農芸化学会大会トピックス賞
2019/03 - (公)日本農芸化学会大会トピックス賞
2004 - (財)山下太郎顕彰育英会学術研究奨励賞

Association Membership(s) (5)：

東北植物学会 , THE BOTANICAL SOCIETY OF JAPAN , JAPANESE SOCIETY FOR PLANT CELL AND MOLECULAR BIOLOGY , THE JAPANESE SOCIETY OF PLANT PHYSIOLOGISTS , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

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