KAZUYA KOUMOTO

コウモトカズヤ | KAZUYA KOUMOTO

Affiliation and department：
Homepage URL (2)： http://www.konan-first.jp/ , http://www.konan-fiber.jp/

Research field (5)： Applied biofunctional and bioprocess engineering , Food sciences , Bioorganic chemistry , Biochemistry , Synthetic organic chemistry

Research keywords (3)： beta-1,3-glucan , Betaine , 生物有機化学

Research theme for competitive and other funds (5)：

2010 - 2011 Understanding of stabilization and activation mechanism for biomolecules induced by the addition of cellular metabolite analogs
2008 - 2011 細胞内代謝産物群を利用した酵素活性化
2008 - 2009 Understanding of cellular function of compatible solutes utilizing a synthetic approach
2005 - 2007 Investigations of the molecular crowding effect on nucleic acid structures and development of nucleotide switches
2004 - 機能性核酸コンジュゲートの合成

Papers (28)：

Minami Fukuchi, Kotaro Oyama, Hiroaki Mizuno, Akihisa Miyagawa, Kazuya Koumoto, Gaku Fukuhara. Hydrostatic Pressure-Regulated Cellular Calcium Responses. Langmuir : the ACS journal of surfaces and colloids. 2021. 37. 2. 820-826
Yuki Nonoguchi, Ayumu Kodama, Rika Unesaki, Nanako Doi, Toshio Suzuki, Kazuya Koumoto. Modification of the Release Rate of Curcumin from the Cavity of Renatured beta-1,3-1,6-Glucan Nanoparticles by Changing the Molecular Weight of the Constituent Polysaccharide Chains. CHEMISTRY LETTERS. 2020. 49. 10. 1150-1153
Shodai Hino, Rikushi Funada, Kouta Sugikawa, Riku Kawasaki, Kazuya Koumoto, Toshio Suzuki, Takeshi Nagasaki, Atsushi Ikeda. Mechanism toward Turn-on of Polysaccharide-Porphyrin Complexes for Fluorescence Probes and Photosensitizers in Photodynamic Therapy in Living Cells. CHEMMEDCHEM. 2020. 16. 5. 793-803
Ayumu Kodama, Akifumi Nakagawa, Yuki Nonoguchi, Haruka Sakurai, Chieko Yano, Toshio Suzuki, Kazuya Koumoto. Solubilization of poorly water-soluble bioactive molecules in neutral aqueous media by complexation with renatured beta-1,3-1,6-glucan nanoparticles. BIOPOLYMERS. 2020. 111. 4. e23349
Takuma Aoki, Yuichi Nakagawa, Ryutaro Genjima, Kazuya Koumoto. Structural effect of amine N-oxides on the facilitation of alpha-glucosidase-catalyzed hydrolysis reactions. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 2020. 43. 3. 541-548

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MISC (69)：

Atsushi Ikeda, Motofusa Akiyama, Kouta Sugikawa, Kazuya Koumoto, Yuta Kagoshima, Jiawei Li, Toshio Suzuki, Takeshi Nagasaki. Formation of beta-(1,3-1,6)-D-glucan-complexed [70]fullerene and its photodynamic activity towards macrophages (vol 15, pg 1990, 2017). ORGANIC & BIOMOLECULAR CHEMISTRY. 2017. 15. 45. 9734-9734
Eisuke Deguchi, Kazuya Koumoto. Cellular zwitterionic metabolite analogs simultaneously enhance reaction rate, thermostability, salt tolerance, and substrate specificity of alpha-glucosidase. BIOORGANIC & MEDICINAL CHEMISTRY. 2011. 19. 10. 3128-3134
Molecular receptor for saccharide recognition: boronic acid. Bio industry. 2010. 27. 2. 18-23
甲元一也, 新海征治. 糖分子を認識する人工レセプター:ボロン酸. バイオインダストリー. 2010. 27. 2. 66-72
Li Wu, Kazuya Koumoto, Naoki Sugimoto. Reversible stability switching of a hairpin DNA via a photo-responsive linker unit. CHEMICAL COMMUNICATIONS. 2009. 14. 1915-1917

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Patents (19)：

酵素活性を向上させるための組成物およびその利用
核酸合成を促進する化合物を含む組成物およびその利用、並びに当該化合物の製造方法
ハイブリッド多糖系キャリアーを用いる核酸類の導入方法
ポリエチレングリコールまたはポリプロピレングリコール修飾β-1,3-グルカン系遺伝子キャリアー
新規な遺伝子導入剤

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Books (2)：

絵で見てわかるナノDDS 遺伝子医学MOOK別冊
メディカルドゥ 2007
Macromolecular Nanostructured Material
Springer 2004

Education (3)：

- 2000 Kyushu University
- 1997 Kyushu University
- 1995 Kyushu University School of Engineering

Professional career (1)：

博士(工学) (九州大学)

Work history (7)：

2018/04 - 現在 Konan University Faculty of Frontiers of Innovative Research in Science and Technology Department of Nanobiochemistry Professor
2009 - 2018/03 甲南大学フロンティアサイエンス学部生命化学科准教授
2004 - 2009 Konan University Frontier Institute for Biomolecular Engineering Research
2002 - 2004 The University of Kitakyushu Faculty of Environmental Engineering
2002 - 2002 Kyushu University Faculty of Engineering

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Committee career (1)：

2010 - 有機合成化学協会幹事

Association Membership(s) (7)：

生物工学会 , 有機合成化学協会 , 生命化学研究会 , 生体機能関連部会 , アメリカ化学会 , 高分子学会 , 日本化学会

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