Kuwahara Shigefumi

クワハラシゲフミ | Kuwahara Shigefumi

Affiliation and department：
Job title： Professor
Homepage URL (1)： https://www.agri.tohoku.ac.jp/yuuki/seibutsuyuki/index.html

Research field (3)： Conservation science (plants) , Structural/physical organic chemistry , Bioorganic chemistry

Research keywords (6)： Insecticide , Plant Growth regulator , Antimicrobial Substance , Cyototoxin , Antitumor Substance , Organic Synthesis

Research theme for competitive and other funds (19)：

2000 - 現在 Synthesis of Antitumor Substances, Antimibrobial Substances, Insecticides, and Plant Growth Regulators
1984 - 現在 Synthesis of Insect Pheromones and Phytoalexins
2020 - 2023 強力な抗菌活性を有する特異構造天然物の全合成と構造活性相関及び化学生物学的展開
2017 - 2020 Synthetic studies on anti-infective natural products with unique structures for developing new categories of medicinal drugs
2014 - 2018 Chemical studies on the antifeedants in the skin secretion of the ranid frog Grandilana rugosa against predatory snakes

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Papers (209)：

Hiroki Asao, Yasuharu Shimasaki, Ayaka Sasaki, Shunki Katayama, Kousuke Ida, Masaaki Kotake, Eriko Sato, Yuki Sato, Taiki Ishimoto, Minoru Izumi, et al. Synthesis of the A/D/E-ring Core Compounds of Maoecrystal V†. Bioscience, biotechnology, and biochemistry. 2024. 88. 7. 733-741
Osamu Ishibashi, Yasuhiro Meguro, Shigefumi Kuwahara, Masaru Enomoto. Two Synthesis Approaches of the 2H-Tetrahydro-4,6-dioxo-1,2-oxazine Ring System of Alchivemycins A and B. European Journal of Organic Chemistry. 2023
Kohei Kuji, Misaki Kawamoto, Masaru Enomoto, Kuwahara Shigefumi, Yasuhiro Meguro. Enantioselective synthesis of the aglycone of burnettramic acid A. Bioscience, Biotechnology, and Biochemistry. 2023
Yasuhiro Meguro, Masaru Enomoto, Shigefumi Kuwahara. Synthesis of the N -Amykitanosyl Tetramic Acid Moiety of Amycolamicin. European Journal of Organic Chemistry. 2023
Tomoyo Mohri, Shigefumi Kuwahara, Yusuke Ogura. Synthetic Studies of Bioactive Oxacyclic Natural Products. Journal of Synthetic Organic Chemistry, Japan. 2023. 81. 2. 115-126

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MISC (28)：

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Patents (2)：

Books (3)：

第4版マクマリー生物有機化学基礎化学編
丸善 2015
Fundamentals of General, Organic, and Biological Chemistry
丸善 2007
New Discoveries in Agrochemicals (ACS Symposium Series 892)
American Chemical Society 2005

Lectures and oral presentations (361)：

Total synthesis of aculenes, norsesquiterpenes showing quorum sensing inhibitory activity
(2022)
Bioinspired total synthesis of rossinone B, a bioactive meroterpenoid isolated from an Antarctic ascidian
(2022)
Total synthesis of amycolamicin, a potent broad-spectrum antibiotic
(2022)
Synthesis of the A and DE units of amycolamicin, a potent broad-spectrum antibiotic
(2022)
Synthesis and structural revision of cremenolide
(International Chemistry Congress of Pacific Basin Societies 2021 (Pacifichem 2021) 2021)

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Education (2)：

- 1984 The University of Tokyo Graduate School, Division of Agricultural Science 農芸化学専門課程
- 1980 The University of Tokyo Faculty of Agriculture 農芸化学科

Professional career (2)：

Work history (10)：

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Committee career (36)：

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Awards (6)：

2023/02 - Synthetic Organic Chemistry Award, Japan
2021/04 - The Yomiuri Prize of Agricultural Science Synthetic studies on bioactive natural products of agricultural and medicinal importance
2021/04 - Japan Prize of Agricultural Science Synthetic studies on bioactive natural products of agricultural and medicinal importance
2013/03/24 - 公益社団法人日本農芸化学会 BBB Most-Cited Paper Award
2006/03/25 - (社)日本農芸化学会 BBB論文賞

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Association Membership(s) (5)：

アジア・太平洋化学生態学会 , 日本農薬学会 , 有機合成化学協会 , アメリカ化学会 , 日本農芸化学会

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