Rchr
J-GLOBAL ID:200901069807767028
Update date: Sep. 16, 2024
Kuroki Masahide
クロキ マサヒデ | Kuroki Masahide
Homepage URL (2):
http://www.med.fukuoka-u.ac.jp/biochem1/doukouichiran.html
,
http://www.med.fukuoka-u.ac.jp/biochem1/index-j.htm
Research field (3):
Pathobiochemistry
, Tumor diagnostics and therapeutics
, Tumor diagnostics and therapeutics
Research keywords (13):
Cancer
, Viroimmunotherapy
, Photoimmunotherapy
, Sonoimmunotherapy
, Monoclonal Antibody
, Human Monoclonal Antibody
, Epithelial Cell Adhesion Molecule
, Thrombospondin-1
, Carcinoembryonic Antigen
, Tumor Marker
, Immunoassay
, Tumor-associated Antigen
, Immunogene Therapy
Research theme for competitive and other funds (30):
- 2014 - 2015 Targeted photoimmunotherapy of cancer using a near-infrared photosensitizer, IR700, conjugated with human anti-CEA antibody
- 2008 - 2013 Targeting of gene therapy for digestive cancer with anti-tumor antibodies
- 2008 - 2011 Study on the usefulness of the novel tumor marker MK-1 in the diagnosis and therapy of cancer
- 2006 - 2008 Generation and application of fully human antibodies to a new tumor-associated antigen, Ep-CAM
- 2002 - 2007 Establishment of novel immunotherapy and gene therapy for digestive cancer
- 2006 - 2007 Combination therapy for digestive cancer with fully human anti-CEA antibody and anticancer agent
- 2004 - 2006 Significance of a new tumor-associated antigen, MK-1, for diagnosis and therapy of cancer
- 2005 - 2006 Targeted therapy of gastrointestinal cancer using human anti-CEA antibody
- 2002 - 2004 Generation and application of human monoclonal antibodies for tumor-associated antigens by using human chromosome transferred mice
- 2001 - 2003 Improvement of cancer gene therapy with specific anti-tumor antibodies
- 2000 - 2002 A specific study for clinical application of a new tumor-associated antigen, MK-1
- 1996 - 2002 Novel diagnostic and therapeutic strategies for cancer by genetic engineering
- 1998 - 2000 The analysis of the gene and protein expression levels of a new tumor-associated antigen, TSP-1
- 1995 - 1997 Basic study on missile therapy and gene therapy for cancer using tumor-associated antigens as targets
- 1994 - 1996 Study on biological proteins by genetic engineering (II)
- 1994 - 1996 Cloning of cDNA and establishment of an assay system for Mr 110,000 Ag
- 1991 - 1994 Study on biological proteins by genetic engineering (I)
- 1991 - 1994 Production and releasing mechanism of CEA in normal colon mucosa
- 1990 - 1991 Establishment of immunoassay system with high sensitivity for tumor markers and re-evaluation of existing immunoassay system
- 1990 - 1991 Production and releasing mechanism of CEA associated with malignant transformation of cells in normal mucosa
- 1989 - 1990 Comparative studies of the structure and behavior of CEA between normal and tumor tissues
- 1990 - 1990 粘膜上皮細胞の分化並びに癌化に伴うCEA及び関連抗原の産生動態の変化
- 1989 - 1989 癌胎児性抗原(CEA)の癌特異性の本態の解明
- 1986 - 1988 Preparation of site-specific antibodies by a novel immunization procedure involving induction of tolerance to cross-reacting determinants and its utilization
- 1985 - 1986 Preparation and characterization of monoclonal antibodies to the carbohydrate chains of cancer cells and antigens
- 1983 - 1984 Analysis of molecular structure mutation of carcinoembryonic antigen associated with the differentiation and malignant transformation of cells
- 1983 - 1984 Generation and characterization of monoclonal antibodies against cancer-specific antigenic determinants
- 1982 - 1983 Preparation of monoclonal antibodies by cell-fusion technique and analysis of antigenic structure of CEA with them
- 1981 - 1982 Analysis of molecular structure mutation of glycoproteins associated with the differentiation and malignant transformation of cells
- 1978 - 1979 Study on production mechanism and physiological significance of normal fecal antiben
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Papers (443):
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Shirasu N, Shibaguchi H, Yamada H, Kuroki M, Yasunaga S. Highly versatile cancer photoimmunotherapy using photosensitizer-conjugated avidin and biotin-conjugated targeting antibodies. Cancer cell international. 2019. 19. 299
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Izuchi D, Fukagawa S, Yotsumoto F, Shigekawa K, Yoshikawa K, Hirakawa T, Kiyoshima C, Ouk NS, Urushiyama D, Katsuda T, et al. Association of Serum HB-EGF Value and Response to Chemotherapy in Patients with Recurrent Ovarian Cancer. Anticancer Research. 2018. 38. 7. 4347-4351
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Madoka Naemura, Masahide Kuroki, Toshiyuki Tsunoda, Nagisa Arikawa, Yuuga Sawata, Senji Shirasawa, Yojiro Kotake. The long noncoding RNA OIP5-AS1 is involved in the regulation of cell proliferation. Anticancer Research. 2018. 38. 1. 77-81
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Toshihiro Tanaka, Hiromi Yamada, Masahide Kuroki, Shohta Kodama, Kazuo Tamura, Yasushi Takamatsu. A Modified Adenovirus Vector-Mediated Antibody Screening Method Identifies EphA2 as a Cancer Target. TRANSLATIONAL ONCOLOGY. 2017. 10. 4. 476-484
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Kohei Miyata, Fusanori Yotsumoto, Satoshi Fukagawa, Chihiro Kiyoshima, Nam Sung Ouk, Daichi Urushiyama, Tomohiro Ito, Takahiro Katsuda, Masamitsu Kurakazu, Ryota Araki, et al. Serum Heparin-binding Epidermal Growth Factor-like Growth Factor (HB-EGF) as a Biomarker for Primary Ovarian Cancer. ANTICANCER RESEARCH. 2017. 37. 7. 3955-3960
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MISC (133):
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黒木政秀. 少子化が進日本で若い人たちへ望むこと. 人高の澪:先輩から後輩へのメッセージ. 2023. 2. 1. 66-67
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宮本 新吾, 黒木 政秀. HB-EGF発現調節機構に関与する分子機構の解明. 福岡大学研究部論集. F, 推奨研究編 : 推奨研究プロジェクト成果報告書 = The bulletin of Central Research Institute Fukuoka University. 2015. 2. 94-97
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Kuroki M. A increase in the quota of students in medical school and a yearly medical licensing examination in Japan (in Japanese). Fukuoka University Medical Society News. 2015. 71. 1. 2
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Satoshi Fukagawa, Sung Ouk Nam, Fusanori Yotsumoto, Kohei Miyata, Masahide Kuroki, Shingo Miyamoto. VALIDATION OF ANTITUMOR EFFECT BY INTRAVENOUS ADMINISTRATION OF CRM197 IN TRIPLE NEGATIVE BREAST CANCER. ANTICANCER RESEARCH. 2014. 34. 10. 6063-6064
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Kohei Miyata, Fusanori Yotsumoto, Song Ouk Nam, Satoshi Fukagawa, Masahide Kuroki, Shingo Miyamoto. TRANSLATIONAL REGULATION OF HB-EGF MRNA VIA A TRANSLATIONAL REGULATOR, RBM8A. ANTICANCER RESEARCH. 2014. 34. 10. 6063-6063
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Patents (13):
Books (48):
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モデル・コア・カリキュラム対応医用生化学 : 生体物質の代謝と異常 2024年版
福岡大学医学部生化学講座 2024 ISBN:9784990942670
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モデル・コア・カリキュラム対応医用生化学 : 生体物質の代謝と異常 2023年版
福岡大学医学部生化学講座 2023 ISBN:9784990942663
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モデル・コア・カリキュラム対応 医用生化学 生体物質の代謝と異常 2022年版
福岡大学医学部生化学講座 2022 ISBN:9784990942656
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モデル・コア・カリキュラム対応 医用生化学 生体物質の代謝と異常 2021年版
福岡大学医学部生化学講座 2021 ISBN:9784990942649
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モデル・コア・カリキュラム対応 医用生化学 生体物質の代謝と異常 2020年版
福岡大学医学部生化学講座 2020 ISBN:9784990942632
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Lectures and oral presentations (413):
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Screening of microRNA as a prognosis factor for ovarian cancer
(74th Annual Meeting of the Japanese Cancer Association 2015)
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Enhancement of antitumor activity on sonodynamic therapy in combination with a sonosensitizer, DEG, and microbubble
(74th Annual Meeting of the Japanese Cancer Association 2015)
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Integrative and cooperative photoimmunotherapy for cancer using avidin-conjugated near infrared photosensitizer
(74th Annual Meeting of the Japanese Cancer Association 2015)
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Identification of the molecules involved in translational control of HB-EGF as a cancer therapeutic target molecule (in Japanese)
(18th Annual Meeting of the Society of Biotherapeutic Approaches 2014)
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Validity of HB-EGF as a new target molecule for neuroblastoma (in Japanese)
(18th Annual Meeting of the Society of Biotherapeutic Approaches 2014)
more...
Education (2):
- 1982 - 1982 Fukuoka University Graduate School of Medicine Doctor of Medical Science by way of dissertation
- 1969 - 1975 Kumamoto University Faculty of Medicine School of Medicine
Professional career (2):
- 医学士 (熊本大学)
- Doctor of Medical Science (Fukuoka University)
Work history (11):
- 2015 - 現在 Professor Emeritus, Fukuoka University/ Emeritus Member, The Japanese Cancer Association/ Emeritus Member, American Association for Cancer Research
- 2018 - 2022 Contract Professor, Fukuoka College of Health Sciences
- 1994 - 2015 Professor: Fukuoka University School of Medicine
- 2007 - 2011 Dean: School of Medicine, Fukuoka University/ Board of Directors and Board of Councilors, Fukuoka University
- 2005 - 2007 Dean: Graduate School of Medicine, Fukuoka University
- 1998 - 2007 Head Chief: Molecular Oncology Center, Fukuoka University
- 1983 - 1994 Associate Professor: Fukuoka University School of Medicine
- 1986 - 1988 Visiting Associate: National Cancer Institute, National Institutes of Health, USA
- 1983 - 1983 Doctor of Medical Science by way of Dissertation: Graduate School of Medicine, Fukuoka University
- 1978 - 1983 Assistant Professor: Fukuoka University School of Medicine
- 1975 - 1978 Resident: Kumamoto University School of Medicine
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Committee career (30):
- 1999 - 2015 The Society of Biotherapeutic Approaches Board of Councilors
- 1999 - 2015 バイオ治療法研究会(SBA) 幹事
- 2011 - 2014 Linking Setouchi Innate Immune Network Board of Councilors
- 2011 - 2014 特定非営利活動法人環瀬戸内自然免疫ネットワーク 理事
- 2006 - 2014 Anticancer Research Editorial Committee
- 2006 - 2014 Anticancer Research 編集委員
- 2004 - 2014 BMC Cancer Editorial Committee
- 2004 - 2014 Gene Therapy and Molecular Biology Editorial Committee
- 2004 - 2014 Japanese Journal of Clinical Oncology Editorial Committee
- 2004 - 2014 BMC Cancer 編集委員
- 2004 - 2014 Gene Therapy and Molecular Biology (GTMB) 編集委員
- 2004 - 2014 Japanese Journal of Clinical Oncology (JJCO) 編集委員
- 2001 - 2014 Japanese Association of Cancer Immunology Board of Councilors
- 2001 - 2014 日本がん免疫研究会(JACI) 評議員
- 2000 - 2014 Tumor Biology Editorial Committee
- 2000 - 2014 Tumor Biology 編集委員
- 1999 - 2014 Japanese Cancer Association Board of Councilors
- 1999 - 2014 日本癌学会(JCA) 評議員
- 1995 - 2014 Japan Society for Molecular Tumor Marker Research Board of Councilors
- 1995 - 2014 日本分子腫瘍マ-カ-研究会(JSMTMR) 世話人
- 2013 - 2013 The Japan University Accreditation Association University Evaluation Subcommittee
- 2013 - 2013 平成25年度大学基準協会大学評価委員会 評価分科会委員
- 2009 - 2012 Fukuoka Foundation for Sound of Health Board of Councilors
- 2009 - 2012 財団法人福岡県すこやか健康事業団 理事
- 2008 - 2012 The Clinical Rresearch Promotion foundation Board of Councilors
- 2008 - 2012 財団法人臨床研究奨励基金 理事
- 2008 - 2009 Fukuoka Cancer Society Board of Directors
- 2008 - 2009 福岡県対がん協会 常務理事
- 1989 - 2007 The International Society for Oncodevelopmental Biology and Medicine Board of Councilors
- 1989 - 2006 国際腫瘍学バイオマーカー学会(ISOBM) 評議員
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Association Membership(s) (5):
Japanese Association of Cancer Immunology
, The Society of Biotherapeutic Approaches
, Japanese Society for Molecular Tumor Marker Research
, Japanese Cancer Association
, American Association for Cancer Research)
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