Rchr
J-GLOBAL ID：200901073734698534   Update date: Nov. 11, 2024

Okamoto Akimitsu

オカモト アキミツ | Okamoto Akimitsu
Affiliation and department：
The University of Tokyo The Graduate School of Engineering Department of Chemistry and Biotechnology

About The University of Tokyo The Graduate School of Engineering Department of Chemistry and Biotechnology


Job title： Professor
Homepage URL  (1)： https://webpark1516.sakura.ne.jp/
Research field  (10)： Genetics ,  Genomics ,  Space and planetary science ,  Bioorganic chemistry ,  Structural/physical organic chemistry ,  Synthetic organic chemistry ,  Green/sustainable/environmental chemistry ,  Biochemistry ,  Chemical biology ,  Molecular biochemistry
Research keywords  (14)： Nucleic acid therapeutics ,  Dye design ,  Photodynamic Therapy ,  Origin of Life ,  Raman Spectroscopy ,  Cell Interaction ,  Epigenetics ,  Live Cell Imaging ,  In-Cell Organic Chemistry ,  Cell Immobilization ,  Chemical Protein Engineering ,  Nucleic Acid Chemistry ,  Organic Synthesis ,  Bioorganic Chemistry
Research theme for competitive and other funds  (40)：
  • 2023 - 2026 Unprecedented and potent immunoregulation provided by protein capture with functionalized small synthetic nucleic acids
  • 2023 - 2026 Studies on the development of antibody-drug conjugate orphan drugs based on photodynamic therapy targeting oral cancer.
  • 2022 - 2025 特定のヘテロクロマチン領域を認識し遺伝子発現を制御するメカニズムの解明
  • 2021 - 2023 Exploration of the modification of genomic higher-order structures in the cell nucleus by aggregation of chemically synthesized short nucleic acids
  • 2020 - 2023 PCI法を用いた蛍光標識抗体薬物複合体デリバリーによる次世代口腔癌治療法の開発
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Papers (212)：
  • Takafumi Furuhata, Bumkyu Choi, Taiki Uno, Ryota Shinohara, Yusuke Sato, Kei Okatsu, Shuya Fukai, Akimitsu Okamoto. Chemical Diversification of Enzymatically Assembled Polyubiquitin Chains to Decipher the Ubiquitin Codes Programmed on the Branch Structure. Journal of the American Chemical Society. 2024
  • Kenjyo Miyauchi, Satoshi Kimura, Naho Akiyama, Kazuki Inoue, Kensuke Ishiguro, Thien-Son Vu, Veerasak Srisuknimit, Kenta Koyama, Gosuke Hayashi, Akiko Soma, et al. A tRNA modification with aminovaleramide facilitates AUA decoding in protein synthesis. Nature Chemical Biology. 2024
  • Minako Narita, Ai Kohata, Taiichi Kageyama, Honoka Watanabe, Kohsuke Aikawa, Daisuke Kawaguchi, Kunihiko Morihiro, Akimitsu Okamoto, Takashi Okazoe. Fluorocarbon-DNA Conjugates for Enhanced Cellular Delivery: Formation of a Densely Packed DNA Nano-Assembly. ChemBioChem. 2024
  • Shinya Yamahira, Hidefumi Mitsuno, Misato Yamaoka, Teruyuki Nagamune, Akimitsu Okamoto, Ryohei Kanzaki, Satoshi Yamaguchi. Odorant-sensing cell micropatterns for odor discrimination. Biosensors and Bioelectronics: X. 2024. 18. 100473
  • Kunihiko Morihiro, Yasuhiro Tomida, Honami Ando, Akimitsu Okamoto. Copper-mediated siRNA activation for conditional control of gene expression. Bioorganic & Medicinal Chemistry Letters. 2024. 104. 129738-129738
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MISC (56)：
  • 増井周造, 門屋祥太郎, 道畑正岐, 小阪高広, 山口哲志, 岡本晃充, 高橋哲. 局在光制御によるセルインマイクロファクトリに関する基礎的研究(第8報)-ストレプトアビジン,ビオチン相互作用を用いたマイクロ粒子接着-. 精密工学会大会学術講演会講演論文集(CD-ROM). 2022. 2022
  • 渡邉ほの香, 相川光介, 森廣邦彦, 岡本晃充, 岡添隆, 岡添隆. Synthesis of fluorine containing oligonucleotides for cell membrane permeability and their assay. 日本化学会春季年会講演予稿集(Web). 2021. 101st
  • 梅田侑生, 山口哲志, 山平真也, 中村元直, 岡本晃充, 岡本晃充. Cell Membrane Sheet Array for Quantitative Single-cell Analysis of the Cytoplasmic Face of Plasma Membranes. 日本化学会春季年会講演予稿集(Web). 2021. 101st
  • Koki Nakatsu, Gosuke Hayashi, Akimitsu Okamoto. Toolbox for chemically synthesized histone proteins. Current Opinion in Chemical Biology. 2020. 58. 10-19
  • 上原廉二朗, 山口哲志, 山口哲志, 小阪高広, 山平真也, 岡本晃充, 岡本晃充. Development of a photo-responsive substrate for cell patterning and collection. 日本化学会春季年会講演予稿集(CD-ROM). 2020. 100th
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Patents (40)：
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Education (4)：
  • - 1998 Kyoto University
  • - 1998 Kyoto University Graduate School, Division of Engineering Department of Synthetic Chemistry and Biological Chemistry
  • - 1993 Kyoto University Faculty of Engineering
  • - 1993 Kyoto University Faculty of Engineering Synthetic Chemistry
Professional career (1)：
  • Doctor of Engineering (Kyoto University)
Work history (9)：
  • 2022/04 - 現在 The University of Tokyo The Graduate School of Engineering Department of Chemistry and Biotechnology Professor
  • 2012/04 - 2022/03 The University of Tokyo RCAST Professor
  • 2012/01 - 2012/03 The University of Tokyo Department of Chemistry and Biotechnology Professor
  • 2011/04 - 2012/01 RIKEN Okamoto Nucleic Acid Chemistry Laboratory Associate Chief Scientist
  • 2006/04 - 2011/03 RIKEN Okamoto Initiative Research Unit Unit Leader
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Awards (8)：
  • 2014 - JSPS 10th JSPS Prize
  • 2008 - Royal Society of Chemistry, Organic & Biomolecular Chemistry Lecture Award
  • 2007 - 平成19年度科学技術分野の文部科学大臣表彰 若手科学者賞
  • 2005 - 日本化学会 進歩賞
  • 2005 - 光科学技術研究振興財団 研究表彰
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Association Membership(s) (11)：
KINKA CHEMICAL SOCIETY ,  日本光医学・光生物学会 ,  THE JAPANESE PHOTOCHEMISTRY ASSOCIATION ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  American Chemical Society ,  THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY ,  THE CHEMICAL SOCIETY OF JAPAN ,  The Japanese Peptide Society ,  Japan Society of Nucleic Acids Chemistry ,  The Japanese Society of Epigenetics ,  Royal Society of Chemistry
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