Rchr
J-GLOBAL ID：200901080729026257   Update date: Apr. 29, 2024

Oishi Shinya

オオイシ シンヤ | Oishi Shinya
Affiliation and department：
京都薬科大学 薬学部

About 京都薬科大学 薬学部


Job title： 教授
Homepage URL  (1)： http://www.pharm.kyoto-u.ac.jp/seizo/home.htm
Research field  (1)： Pharmaceuticals - chemistry and drug development
Research keywords  (3)： ペプチド化学 ,  医薬品化学 ,  創薬科学
Research theme for competitive and other funds  (32)：
  • 2022 - 2026 Development of mirror-image antibody-like scaffolds and their applications
  • 2021 - 2026 Exploration of estrogen feedback mechanisms regulating animal reproduction to improve the methods controlling ovulation and follicle development in domestic animals
  • 2022 - 2024 Development of antibody-mimetic libraries by CDR grafting
  • 2021 - 2024 コロナウイルス制圧のための新規膜融合阻害ペプチドの創出と合理的な設計法の確立
  • 2020 - 2023 抗ウイルス薬シーズ探索のための鏡像スクリーニング系の構築と応用
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Papers (335)：
  • Hiroshi Murakami, Gosuke Hayashi, Toshinori Naito, Sayaka Miura, Naoya Iwamoto, Yusuke Usui, Motohiro Nonaka, Shinya Oishi. High-affinity mirror-image monobody targeting MCP-1 generated via TRAP display and chemical protein synthesis. 2024
  • Keisuke Aoki, Shugo Tsuda, Naoko Ogata, Michiyo Kataoka, Jumpei Sasaki, Shinsuke Inuki, Hiroaki Ohno, Koichi Watashi, Taku Yoshiya, Shinya Oishi. Synthesis of the full-length hepatitis B virus core protein and its capsid formation. Organic & Biomolecular Chemistry. 2024. 22. 11. 2218-2225
  • Ayuta Yamaguchi, Naoki Obiya, Norihito Arichi, Shinya Oishi, Hiroaki Ohno, Shinsuke Inuki. Synthesis of labionin and avionin precursors via a nitrogen-centred-radical-triggered 1,5-HAT reaction of Tris derivatives. Organic & Biomolecular Chemistry. 2024. 22. 10. 2049-2055
  • Kazushige Hirata, Aoi Takahara, Satoshi Suzuki, Shumei Murakami, Kumi Kawaji, Akie Nishiyama, Mina Sasano, Mariko Shoji-Ueno, Emiko Usui, Kazutaka Murayama, et al. Helical peptides with disordered regions for measles viruses provide new generalized insights into fusion inhibitors. iScience. 2024. 27. 2. 108961
  • Naoya Iwamoto, Jumpei Sasaki, Saya Ohno, Keisuke Aoki, Yusuke Usui, Shinsuke Inuki, Hiroaki Ohno, Shinya Oishi. Synthetic studies on the extracellular domain of the T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (TIGIT) using Trt-K10 solubilizing tags. Bioorganic & Medicinal Chemistry. 2024. 99. 117585
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MISC (348)：
  • 鈴木聡志, 天野陽斗, 薄井友輔, 河治久実, 笹野美奈, 西山瑛絵, 平松佳樹, 橋本浩一, 村山和隆, 児玉栄一, et al. Development of novel protein-protein interaction inhibitors against respiratory syncytial virus. 日本小児科学会雑誌. 2023. 127. 2
  • 鈴木聡志, 黒田実央, 河治久実, 村山和隆, 林宏典, 大石真也, 児玉栄一. Blocking protein-protein interactions are applicable to development of novel antiviral agents for SARS-CoV-2. 日本小児科学会雑誌. 2023. 127. 2
  • 山口亞由太, 井貫晋輔, 有地法人, 大石真也, 大野浩章. Construction of Quaternary Carbon Stereocenter of α-Tertiary Amine of Avionin Moiety and Synthetic Study of Microvionin. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 川北百花, 大谷拓也, 服部恭尚, 大石真也, 小林数也. Structure-activity relationship study on the P4 structure of a macrocyclic BACE1 inhibitor. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 岩本直也, 佐々木順平, 青木啓輔, 井貫晋輔, 大野浩章, 大石真也, 大石真也. Synthetic Study of Imuune Checkpoint Molecules. 日本薬学会年会要旨集(Web). 2023. 143rd
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Patents (40)：
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Books (12)：
  • 薬学総合演習-8大疾患対応、分野横断型症例解析-
    2024 ISBN:9784910844268
  • 新しい反応が加速する創薬研究
    Biophilia(アドスリー) 2017
  • スタンダード薬学シリーズII・化学系薬学II(SBO24,25)
    東京化学同人 2016
  • 有機合成ハンドブック第2版 結晶と沪過
    丸善出版 2015
  • 新たな中枢性繁殖制御剤のシーズ:KNDyニューロン
    MPアグロジャーナル(MPアグロ) 2014
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Education (2)：
  • - 2003 Kyoto University
  • - 1998 Kyoto University Faculty of Pharmaceutical Sciences
Professional career (1)：
  • 博士(薬学) (京都大学)
Work history (6)：
  • 2020/04 - 現在 Kyoto Pharmaceutical University Pharmaceutical Sciences Professor
  • 2015/10 - 2020/03 Kyoto University Graduate School of Pharmaceutical Sciences Associate Professor
  • 2009/06 - 2015/09 Kyoto University Graduate School of Pharmaceutical Sciences Senior Lecturer
  • 2006/01 - 2009/05 Kyoto University Graduate School of Pharmaceutical Sciences
  • 2004/06 - 2005/12 University of Shizuoka Graduate School of Pharmaceutical Sciences
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Awards (2)：
  • 2009 - 日本薬学会奨励賞
  • 2003 - 日本薬学会近畿支部奨励賞
Association Membership(s) (4)：
米国化学会 ,  日本ペプチド学会 ,  有機合成化学協会 ,  日本薬学会
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