Research theme for competitive and other funds (21)：
2013 - 2017 Epigenetic effects on the onset of Periventricular Leucomalacia
2012 - 2015 Microglial function in hypoxic-ischemic encephalopathy
2006 - 2008 Genetic analysis of spontaneous animal model of neurodegeneration to study molecular mechanisms underlying selective regional vulnerability
2003 - 2004 Age-related impairments of proteasome activity and neuronal ubiquitinated iclusions in aging mouse brain
2002 - 2004 Molecular Genetic Analysis of Senescence-Accelerated Mouse (SAM)
2002 - 2003 Investigation of the mechanisms of the degeneration and death of neuronal cells using a culture model.
2002 - 2003 Bone Mineral Density and Polymorphism of Candidate Genes Regulating the Onset of Osteoporosis.
1999 - 2000 Establishment of congenic strains of mice carrying a genomic interval which regulates the onset of osteoporotic phenotype.
1997 - 1998 Molecular and Cellular Basis of Senescence Acceleration
1997 - 1998 Studies of the Pathogenesis of Amyloidosis : Verification of the Hypothesis 'Transmission of Abnormal Proteins Structure' Using Mouse Senile Amyloidosis.
1997 - 1998 Identification of quantitative trait loci specifying the onset of osteoporosis using a murine model.
1995 - 1996 Development of the Gene Therapeutic Treatment to Mouse Senile Amyloidosis
1995 - 1995 個体の最大骨量及び骨粗鬆症発症に対する癌遺伝子(c-fos)発現の影響
1991 - 1993 Comprehensive studies on age-related deficits in learning and memory in SAM
1991 - 1992 Molecular genetic analysis of muirne senile amyloidosis.
1990 - 1992 Development of murine models for aging brain, Senescence-Accelerated Mouse (SAM)
1989 - 1990 Molecular Genetic Study of Mouse Senile Amyloidosis
1989 - 1990 Modulatory Effect of Dietary Restriction on the Advance of Senescence in Senescence Accelerated Mouse (SAM)
1987 - 1988 A New Strain of Mice with Late-appearing Cataract, It's development from Senescence Accelerated Mouse (SAM) and characters of cataract.
1986 - 1988 Experimental studies on the pathogenesis and modulation of age-related pathologies in Senescence Acelerated Mouse (SAM).
Atsuyoshi Shimada, Sanae Ishii, Shiro Takei, Noriko Kawamura, Ayako Furukawa, Yoichi Chiba, Masanori Hosokawa. Microglial defects and neurodegeneration in SAMP10 mice: a model of brain aging. NEUROSCIENCE RESEARCH. 2009. 65. S38-S38
Sanae Ishii, Atsuyoshi Shimada, Yoichi Chiba, Keisuke Yoshikawa, Ayako Furukawa, Noriko Kawamura, Masanori Hosokawa. Defective microglia response and vulnerability to excitotoxic insults in the hippocampus of SAMP10 mouse: a model of age-related cerebral degeneration. NEUROSCIENCE RESEARCH. 2008. 61. S151-S151
