Art

J-GLOBAL ID：201802212521815173   Reference number：18A1870485

Developmental defects and aberrant accumulation of endogenous psychosine in oligodendrocytes in a murine model of Krabbe disease

Krabbe病のマウスモデルにおけるオリゴデンドロサイトの内因性サイコシンの発生欠陥と異常蓄積【JST・京大機械翻訳】

Author (11)： Inamura Naoko (Department of Pathology, Institute for Developmental Research, Aichi Human Service Center, 713-8 Kamiya-cho, Kasugai, Aichi 480-0392, Japan) ,  Kito Momoko (Department of Pathology, Institute for Developmental Research, Aichi Human Service Center, 713-8 Kamiya-cho, Kasugai, Aichi 480-0392, Japan) ,  Kito Momoko (Department of Molecular Neurobiology, Nagoya City University School of Medicine, 1 Kawasumi, Mizuho-cho, Mizuho-ku Nagoya, Aichi 467-8601, Japan) ,  Go Shinji (Department of Pathophysiology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701-0192, Japan) ,  Kishi Soichiro (Department of Pathology, Institute for Developmental Research, Aichi Human Service Center, 713-8 Kamiya-cho, Kasugai, Aichi 480-0392, Japan) ,  Hosokawa Masanori (Department of Pathology, Institute for Developmental Research, Aichi Human Service Center, 713-8 Kamiya-cho, Kasugai, Aichi 480-0392, Japan) ,  Asai Kiyofumi (Department of Molecular Neurobiology, Nagoya City University School of Medicine, 1 Kawasumi, Mizuho-cho, Mizuho-ku Nagoya, Aichi 467-8601, Japan) ,  Takakura Nobuyuki (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Takebayashi Hirohide (Division of Neurobiology and Anatomy, Graduate School of Medicine and Dental Science, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata 951-8510, Japan) ,  Matsuda Junko (Department of Pathophysiology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701-0192, Japan) ,  Enokido Yasushi (Department of Pathology, Institute for Developmental Research, Aichi Human Service Center, 713-8 Kamiya-cho, Kasugai, Aichi 480-0392, Japan)
Material： Neurobiology of Disease  (Neurobiol Dis)
Volume： 120  Page： 51-62  Publication year： 2018 
JST Material Number： W1774A  ISSN： 0969-9961  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Krabbe disease (KD), or globoi...

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Thesaurus term： patient ,  gene ,  pathophysiology ,  in vitro experiment ,  *oligodendroglia ,  dysfunction ,  differentiation (biology) ,  pathogenesis ,  myelin ,  Apoptosis ,  Heredity ,  lysosome ,  Erk1/2 ,  *mouse model
Semi thesaurus term： 発症 , 【Automatic Indexing@JST】

Author keywords (6)： Krabbe disease ,  Oligodendrocyte ,  Demyelination ,  Leukodystrophy ,  Sphingolipidoses ,  Lysosomal storage disease

JST classification (2)： Cell physiology in general  (EF02010S) ,  Basic neurology  (GN01020W)

Terms in the title (7)： Krabbe病 ,  マウスモデル ,  オリゴデンドロサイト ,  内因性 ,  サイコシン ,  欠陥 ,  蓄積