Rchr
J-GLOBAL ID：200901083805902257
Update date: Feb. 01, 2024
Kiuchi Kazutoshi
キウチ カズトシ | Kiuchi Kazutoshi
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Affiliation and department：
Gifu University
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Research field (2)：
Neuroscience - general
, Cell biology
Research keywords (22)：
ER stress
, neprilysin
, amyloid beta
, Molecular Biology
, Intracellular Signal Transduction
, Cellular Neuroscience
, 遺伝子発現
, 神経伝達物質
, ドーパミン神経
, アストロサイト
, マクロファージ
, MPTP
, ゴルジ体
, 転写調節
, 神経栄養因子
, グリア細胞
, 誘導型NO合成酵素
, 翻訳後修飾
, 線条体
, プロモーター
, ミクログリア
, GDNF
Research theme for competitive and other funds (9)：
2007 - 2009 神経損傷時におけるグリア細胞由来神経栄養因子遺伝子の発現様式の解析
2007 - 2008 Expression mechanisms of glial cell line-derived neurotrophic factor (GDNF) under inflammatory conditions
2007 - 2008 Analysis of regulatory mechanisms of glial cell line-derived neurotrophic factorgene expression during nerve injury
2004 - 2007 生体の持つストレス応答機能を利用した老化制御、予防研究
2007 - System biological analysis of gene expression in mammalian cells suffered from endoplasmic reticulum stress
2007 - 小胞体ストレスにより誘導される遺伝子の発現メカニズムの解析
2006 - Search for activating factors of neprilysin and analysis of their induction mechanisms
2006 - ネプリライシンの酵素活性に影響を及ぼす物質の探索とその有効物質の作用機序の解明
1994 - 1995 Role of Glial Inducible Nitric Oxide Synthase (iNOS) in Focal Brain Injury
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Papers (63)：
Junpei Norisada, Yoko Hirata, Fumimasa Amaya, Kazutoshi Kiuchi, Kentaro Oh-hashi. A sensitive assay for the biosynthesis and secretion of MANF using NanoLuc activity. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014. 449. 4. 483-489
Kentaro Oh-hashi, Yoshiro Kanamori, Yoko Hirata, Kazutoshi Kiuchi. Characterization of V-ATPase inhibitor-induced secretion of cysteine-rich with EGF-like domains 2. CELL BIOLOGY AND TOXICOLOGY. 2014. 30. 3. 127-136
Kentaro Oh-Hashi, Yoko Hirata, Kazutoshi Kiuchi. Transcriptional regulation of mouse mesencephalic astrocyte-derived neurotrophic factor in Neuro2a cells. CELLULAR & MOLECULAR BIOLOGY LETTERS. 2013. 18. 3. 398-415
Kentaro Oh-Hashi, Tomomi Tejima, Yoko Hirata, Kazutoshi Kiuchi. Characterization of the 5'-flanking region of the mouse asparagine-linked glycosylation 12 homolog gene. CELLULAR & MOLECULAR BIOLOGY LETTERS. 2013. 18. 3. 315-327
Kentaro Oh-hashi, Yuki Nomura, Kiyo Shimada, Hisashi Koga, Yoko Hirata, Kazutoshi Kiuchi. Transcriptional and post-translational regulation of mouse cation transport regulator homolog 1. MOLECULAR AND CELLULAR BIOCHEMISTRY. 2013. 380. 1-2. 97-106
ｍore...
MISC (103)：
Kentaro Oh-Hashi, Ryosuke Kunieda, Yoko Hirata, Kazutoshi Kiuchi. Biosynthesis and secretion of mouse cysteine-rich with EGF-like domains 2. FEBS Letters. 2016. 585. 2481-2487
Junpei Norisada, Yoko Hirata, Fumimasa Amaya, Kazutoshi Kiuchi, Kentaro Oh-Hashi. A Comparative Analysis of the Molecular Features of MANF and CDNF. PLOS ONE. 2016. 11. 1
Takahiro Hikiji, Junpei Norisada, Yoko Hirata, Kensuke Okuda, Hideko Nagasawa, Shinsuke Ishigaki, Gen Sobue, Kazutoshi Kiuchi, Kentaro Oh-hashi. A highly sensitive assay of IRE1 activity using the small luciferase NanoLuc: Evaluation of ALS-related genetic and pathological factors. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015. 463. 4. 881-887
Kentaro Oh-hashi, Azumi Sone, Takahiro Hikiji, Yoko Hirata, Michela Vitiello, Monica Fedele, Shinsuke Ishigaki, Gen Sobue, Kazutoshi Kiuchi. Transcriptional and post-transcriptional regulation of transmembrane protein 132A. MOLECULAR AND CELLULAR BIOCHEMISTRY. 2015. 405. 1-2. 291-299
Kentaro Oh-hashi, Junpei Norisada, Yoko Hirata, Kazutoshi Kiuchi. Characterization of the role of MANF in regulating the secretion of CRELD2. Biological and Pharmaceutical Bulletin. 2015. 38. 5. 722-731
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Patents (6)：
オキシインドール誘導体及び神経細胞死抑制剤
非ヒト由来の生体試料の特定部位検出方法、非ヒト由来の生体試料の生理学的測定方法、生体試料の特定部位検出装置、光ファイバ保持装置
神経刺激電極とこれを用いた細胞培養装置
生体試料の特定部位検出方法、生体試料の生理学的測定方法、生体試料の特定部位検出装置、光ファイバ保持装置
ビオプテリン,ネオプテリン及び天然プテリジンの酵素免疫測定法及びそのための支持体
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Books (1)：
生物と科学
培風館 2018
Education (5)：
1976 - 1980 名古屋大学大学院医学研究科生理系生化学専攻
- 1980 Nagoya University Graduate School, Division of Medicine
1974 - 1976 Waseda University Graduate School of Science and Engineering
1970 - 1974 Waseda University School of Science and Engineering
- 1974 Waseda University Faculty of Science and Engineering Applied Chemistry
Professional career (1)：
(BLANK) (Nagoya University)
Work history (10)：
2018/04 - 現在 Gifu University Life Science Research Center Specially-appointed Professor
2016/04 - 2018/03 Gifu University
1999/12 - 2016/03 Gifu University Faculty of Engineering
1993/10/01 - 2001/09/30 理化学研究所バイオ・ミメティックコントロール研究センター運動遺伝子研究チーム チームリーダー
1993 - 1999 THe Institute of Physical and Chemical Research(RIKEN), Head
1999 - - Gifu University, Professor
1989/11/01 - 1993/09/30 Nagoya University Radioisotope Research Center
1989 - 1993 Nagoya University, Lecturer
1980/04/01 - 1989/10/31 Nagoya University School of Medicine
1980 - 1989 Nagoya University, Research Assistant
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Committee career (1)：
2001 - 日本生化学会 評議員
Association Membership(s) (4)：
The Society for Neuroscience
, The Japanese Biochemical Society
, 北米神経科学会
, 日本神経科学会
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