Rchr
J-GLOBAL ID：201201029326182798
Update date: Nov. 20, 2024
Shintani Seine
シンタニ セイネ | Shintani Seine
Affiliation and department：
Job title：
Associate Professor
Homepage URL (2)：
https://research-db.chubu.ac.jp/chbhp/KgApp/k03/resid/S002311?lang=ja
,
https://research-db.chubu.ac.jp/chbhp/KgApp/k03/resid/S002311?lang=en
Research field (5)：
Biomedical engineering
, Cell biology
, Bio-, chemical, and soft-matter physics
, Physiology
, Biophysics
Research theme for competitive and other funds (24)：
- 2023 - 2024 Preparatory Research for the Development of Dark and Baryon Emulator (DaBE)
- 2023 - 2024 Live imaging analysis for the mitochondrial metabolism-associated mechanism of metastasis
- 2023 - 2024 Examination and practice of how to utilize AI to develop "skills that should be developed"
- 2022 - 2023 Clarification of normal heartbeat mode based on myocardial contraction rhythm characteristics to detect pioneering signs of heart disease
- 2022 - 2023 Examination of efficiency improvement of education and research activities in the field of biomedical science by learning artificial intelligence AIL
- 2022 - 2023 Development of a sample holder for electron microscope live imaging for pre-disease diagnosis
- 2022 - 2023 Practical application of in-situ precision measurement method for nanoscale biological dynamics
- 2020 - 2023 Development of tracking integrated Raman spectroscopy to measure myosin state distribution in a sarcomere under physiological environment
- 2021 - 2022 Curriculum formulation for the development and dissemination of artificial intelligence technology that improves the quality and productivity of medical practice
- 2021 - 2022 Development of an electron microscope sample holder for pre-disease diagnosis
- 2020 - 2021 Formulation of methods to introduce programming and artificial intelligence technology into the field of education and research in life and medical sciences
- 2019 - 2020 Development of bioactuator that effectively uses heat using myocardium
- 2017 - 2020 Development of real-time coding imaging method for minimally invasive in vivo nano measurement of the heart
- 2019 - 2020 Development of a multimodal nonlinear optical microscope using femtosecond infrared laser pulses
- 2019 - 2020 Education / environment construction for life science students to acquire programming and artificial intelligence technology
- 2017 - 2020 Development of real-time coding imaging method for minimally invasive in vivo nano measurement of the heart
- 2018 - 2019 Curriculum development for life science students to acquire programming and artificial intelligence technology
- 2018 - 2019 Elucidation of myocardial contraction mechanism by electron microscope multi-scale live imaging
- 2015 - 2018 Elucidating the role of high-speed self-excited oscillations on the heartbeat using cross-layer measurement from one molecule to heart
- 2014 - 2017 Development of a ratiometric fluorescent thermosensor sheet for non-invasive temperature mapping at single-cell level
- 2010 - 2016 Regulatory Basis of Biomotility: Chemo-mechanical Feedback Loop
- 2013 - 2014 高精度単一サルコメア長計測によるラット幼若心筋細胞の収縮振動調節メカニズムの解明
- 2013 - 2014 収縮運動特性に基づくiPS細胞由来心筋細胞の分化達成度合い評価法
- 2012 - 2013 ラット幼若心筋細胞内のサルコメア自励振動(SPOC)解析による「自律的心拍制御メカニズム」の解明
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Papers (43)：
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Mahmoud Gallab, Phuc Thi Minh Le, Seine A. Shintani, Hiroaki Takadama, Morihiro Ito, Hisashi Kitagaki, Tomiharu Matsushita, Shintaro Honda, Yaichiro Okuzu, Shunsuke Fujibayashi, et al. Mechanical, bioactive, and long-lasting antibacterial properties of a Ti scaffold with gradient pores releasing iodine ions. Biomaterials Advances. 2024. 158. 213781-213781
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Seine A. Shintani. Observation of sarcomere chaos induced by changes in calcium concentration in cardiomyocytes. Biophysics and Physicobiology. 2024. 21. 1. e210006
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Seine A. Shintani. Hole behavior captured by analysis of instantaneous amplitude and phase of sarcosynced oscillations reveals wave characteristics of sarcomeric oscillations. Biochemical and Biophysical Research Communications. 2024. 691. 149339-149339
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Seine A Shintani, Seiji Yamaguchi, Hiroaki Takadama. Real-Time Scanning Electron Microscopy of Unfixed Tissue in Solution using a Deformable and Electron-Transmissive Film. Microscopy. 2022. 71. 5. 297-301
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Seine A. Shintani. Hyperthermal sarcomeric oscillations generated in warmed cardiomyocytes control amplitudes with chaotic properties while keeping cycles constant. Biochemical and Biophysical Research Communications. 2022. 611. 8-13
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MISC (41)：
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山口誠二, ELROUBI Mahmoud, 新谷正嶺, 高玉博朗, 松下富春, 北垣壽, 本田新太郎, 奥津弥一郎, 藤林俊介. Effect of Micro-Scale Regulation on in vitro Bioactivity of Selective Laser Melting Titanium loaded with Iodine. 日本バイオマテリアル学会大会予稿集(Web). 2023. 45回. 142-142
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本田 新太郎, 藤林 俊介, 山口 誠二, 奥津 弥一郎, 新谷 正嶺, 松下 富春, 高玉 博朗, 清水 孝彬, 大槻 文悟, 河井 利之, et al. 抗菌性と骨伝導性を制御する傾斜構造を備えた3Dプリントヨウ素処理チタン多孔体の開発と評価. 日本整形外科学会雑誌. 2023. 97. 8. S1717-S1717
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Seine A Shintani. Artificial intelligence to learn (AIL) : How to use AI without having to deal with AI-derived black boxes. 中部大学生命健康科学研究所紀要(Web). 2023. 19. 19. 18-22
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山口誠二, ELROUBI Mahmoud, LE Phuc Thi Minh, LE Phuc Thi Minh, 新谷正嶺, 伊藤守弘, 高玉博朗, 松下富春, 北垣壽, 本田新太郎, et al. ヨウ素イオン徐放性と骨侵入に適した積層造形チタン多孔体の開発~抗菌性及びその安定性評価. 整形外科バイオマテリアル研究会プログラム・抄録集. 2023. 42nd
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本田新太郎, 藤林俊介, 山口誠二, 奥津弥一郎, 新谷正嶺, 松下富春, 高玉博朗, 清水孝彬, 大槻文悟, 河井利之, et al. 抗菌性と骨伝導性を制御する傾斜構造を備えた3Dプリントヨウ素処理チタン多孔体の開発と評価. 日本整形外科学会雑誌. 2023. 97. 8. S1717-S1717
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Patents (2)：
Lectures and oral presentations (3)：
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Deciphering Cardiac Muscle Efficiency Using Supercomputers: Experimental Discovery of Hyperthermal Sarcomeric Oscillations and Integration with Mathematical Models
("Fugaku" Results Creation Acceleration Program 2nd Workshop Supercomputer "Fugaku" Medical and Drug Discovery Utilization Workshop 2024)
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Accelerating Research on Heartbeat Rhythm Robustness Using Deep Learning-Based Symbolic Regression
(The 3rd Chubu University, National Institute for Physiological Sciences and National Institute for Basic Biology Collaborative Seminar "AI and Life Systems" 2022)
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The Origin of High-Speed Contraction Oscillations Induced by Warming Cardiomyocytes
(Protein Research Institute Seminar: 6th Molecular Motor Symposium "The Cutting Edge of Molecular Motor Research" 2016)
Education (1)：
- 2012 - 2015 Waseda University Faculty of Science and Engineering Doctor’s Programs of Advanced Science and Engineering
Professional career (1)：
- Doctor of Science (Waseda Univ.)
Work history (7)：
- 2024/04 - 現在 Chubu University Department of Biomedical Sciences, College of Life and Health Sciences Associate Professor
- 2022/06 - 現在 Nagoya University Institute for Advanced Research Visiting researcher
- 2021/12 - 現在 Chubu University Center for Mathematical Science and Artificial Intelligence Concurrent post
- 2022/04 - 2024/03 Chubu University Department of Biomedical Sciences, College of Life and Health Sciences Senior Assistant Professor
- 2017/11 - 2022/03 Chubu University Department of Biomedical Sciences, College of Life and Health Sciences Assistant professor
- 2015/04 - 2017/10 The University of Tokyo Department of Physics, Graduate School of Science JSPS Research Fellow
- 2012/11 - 2015/03 Waseda University Faculty of Science and Engineering Research Associate
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Committee career (2)：
- 2024/04 - 現在 The Physiological Society of Japan Councilor
- 2022/09 - 現在 Japanese Society for Chronobiology Councilor
Awards (14)：
- 2024/10 - National Institute for Basic Biology: NIBB NIBB AI-Biology Ideathon 2024 2nd Prize The Construction of the Next-Generation Biological Encyclopedia 3.0 through AI, Multi-View Image Analysis, and Data Aggregation
- 2024/09 - T-GEx (Tokai Pathways to Global Excellence) Retreat Camp Future Society Short Presentation Grand Prize The Development of Devices that Go Beyond Treatment and Prevention to "Enhance" the Body
- 2023/12 - Aichi Prefecture, Science and Technology Exchange Foundation, Hibi Science and Technology Foundation 18th Wakashachi Encouragement Award Basic Science Research Division Grand Prize Group Elucidation of Intracellular Molecular Dynamics in Cardiomyocytes by Electron Microscope Live Imaging
- 2023/11 - Evident, Leave a Nest, Biophysical Society of Japan 61st Biophysical Society of Japan Corporate Participation Pitch Contest Evident Award
- 2023/01 - Ministry of Internal Affairs and Communications INNO-vation Disruptive Challenge INNO-β (Acquisition of title)
- 2022/12 - Japanese Society for Chronobiology 29th JSC Excellent Poster Award
- 2022/09 - Leave a Nest, Biophysical Society of Japan 60th Annual Meeting of the Biophysical Society of Japan 1st Pitch Contest for Corporate Participation Inoka Award
- 2022/02 - Ministry of Economy, Trade and Industry AI Quest Excellence Award 2nd Term Overall Excellence Award
- 2022/02 - Ministry of Economy, Trade and Industry AI Quest Excellence Award 2nd Term AI Challenge Excellence Award
- 2021/12 - Ministry of Internal Affairs and Communications INNO-vation Disruptive Destructive Challenge Division, Destructive Challenge, Challenger
- 2021/11 - Ministry of Internal Affairs and Communications INNO-vation Disruptive Challenge Challenger
- 2021/11 - Ministry of Economy, Trade and Industry AI Quest Excellence Award 1st Term AI Challenge Excellence Award
- 2017/07 - The Editorial office of Biophysics and Physicobiology 4th Biophysics and Physicobiology Editors' Choice Award
- 2016/11 - Japanese Society for Chronobiology 23rd JSC Excellent Poster Award
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