Rchr
J-GLOBAL ID：201201045014887480   Update date: Jul. 26, 2024

Uchimura Kenji

ウチムラ ケンジ | Uchimura Kenji
Affiliation and department：
CNRS Université de Lille

About CNRS Université de Lille


Job title： Research Director
Research field  (1)： Medical biochemistry
Research keywords  (7)： プロテオグリカン ,  包括脳ネットワーク ,  硫酸転移酵素 ,  スルファターゼ ,  細胞接着分子 ,  糖鎖 ,  セレクチン
Research theme for competitive and other funds  (8)：
  • 2017 - 2020 Functional analysis of sulfated glycans in ductular reactions
  • 2017 - 2019 血管内皮障害を呈する腎疾患におけるSulf2の機能解析と新たな治療戦略の探求
  • 2015 - 2018 Sulf2-remodeling of heparan sulfate present in brain amyloids
  • 2015 - 2017 Roles of sulfated N-glycans in myelin
  • 2017 - 2017 脳アミロイド斑除去に関わるミクログリアの糖鎖改変による機能制御機構の解明(国際共同研究強化)
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Papers (93)：
  • Kazuchika Nishitsuji, Remi Mito, Midori Ikezaki, Hiromu Yano, Yukio Fujiwara, Eri Matsubara, Taro Nishikawa, Yoshito Ihara, Kenji Uchimura, Naoyuki Iwahashi, et al. Impacts of cytoplasmic p53 aggregates on the prognosis and the transcriptome in lung squamous cell carcinoma. Cancer science. 2024
  • Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O Akama, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura. GlcNAc6ST2/CHST4 Is Essential for the Synthesis of R-10G-Reactive Keratan Sulfate/Sulfated N-Acetyllactosamine Oligosaccharides in Mouse Pleural Mesothelium. Molecules (Basel, Switzerland). 2024. 29. 4
  • 西辻 和親, 御任 玲美, 池崎 みどり, 藤原 章雄, 岩橋 尚幸, 井原 義人, 内村 健治, 菰原 義弘. p53変異癌における細胞内p53凝集体の予後への影響(Correlation of the presence of cytoplasmic p53 aggregates with poor prognosis in p53-mutated cancers). 日本病理学会会誌. 2024. 113. 1. 341-341
  • Yuki Takechi-Haraya, Takashi Ohgita, Akiko Usui, Kazuchika Nishitsuji, Kenji Uchimura, Yasuhiro Abe, Ryuji Kawano, Monika I. Konaklieva, Mart Reimund, Alan T. Remaley, et al. Structural flexibility of apolipoprotein E-derived arginine-rich peptides improves their cell penetration capability. 2023
  • Bilal Hussain, Vivek Kasinath, Gabriel P. Ashton-Rickardt, Thomas Clancy, Kenji Uchimura, George Tsokos, Reza Abdi. High endothelial venules as potential gateways for therapeutics. Trends in Immunology. 2022. 43. 9. 728-740
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MISC (63)：
  • 原矢佑樹, 扇田隆司, 臼井明子, 西辻和親, 西辻和親, 内村健治, 阿部康弘, 川野竜司, KONAKLIEVA Monika I, REIMUND Mart, et al. Effect of conformational constraints on apolipoprotein E-derived amphipathic peptide: insight into cell membrane penetration. 日本薬学会年会要旨集(Web). 2024. 144th
  • 西辻和親, 西辻和親, 内村健治. Pathological roles of glycosaminoglycans in conformational diseases regulated by sulfation modifications. 生化学. 2024. 96. 2
  • 西辻和親, 池崎みどり, 藤本正数, 岩橋尚幸, 内村健治, 井原義人. Analysis of the CL40-reactive sialylated glycans in ovarian cancer associated with lipid droplet accumulation. 日本糖質学会年会要旨集. 2023. 42nd
  • 西辻和親, 池崎みどり, 内村健治, 内村健治, 岩橋尚幸, 西岡香穂, 藤原章雄, 菰原義弘, 井箟一彦, 井原義人. Sulfated glycosaminoglycan-mediated spreading of p53 amyloid and its contribution to cancer pathology. 日本糖質学会年会要旨集. 2022. 41st
  • 池崎みどり, 西辻和親, 眞鍋史乃, 眞鍋史乃, 内村健治, 内村健治, 伊藤幸成, 伊藤幸成, 井原義人. C-Mannosylated peptide attenuates astrocyte-induced synaptogenesis in rat cortical neurons. 日本糖質学会年会要旨集. 2022. 41st
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Patents (6)：
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Education (1)：
  • 1996 - 1999 Nagoya University Graduate School of Medicine
Professional career (1)：
  • 博士(医学) (名古屋大学)
Work history (5)：
  • 2018 - 現在 Unité de Glycobiologie Structurale et Fonctionnelle, CNRS UMR 8576, Université de Lille
  • 2011 - 2018 Nagoya University Graduate School of Medicine Associate Professor
  • 2006 - 2011 National Center for Geriatrics and Gerontology Section Chief
  • 2001 - 2006 University of California San Francisco Department of Anatomy, Program in Immunology
  • 1999 - 2001 Nagoya University School of Medicine JSPS Research Fellow
Awards (2)：
  • 2011 - Young Investigator Award of Japanese Society of Biochemistry
  • 2006 - Young Investigator Award of Japanese Society of Carbohydrate Research
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