L Fujii Nobuharu

フジイノブハル | L Fujii Nobuharu

Homepage URL (1)： http://www.comp.tmu.ac.jp/muscle/

Research field (3)： Molecular biology , Metabolism and endocrinology , Sports science

Research keywords (9)：再生医療 , メカノバイオロジー , molecular biology , endocrine , myokine , 骨格筋 , 糖尿病 , AMPキナーゼ , 運動

Research theme for competitive and other funds (17)：

2023 - 2027 A myokine network that determines skeletal muscle quality
2021 - 2023 インスリン1および2を欠損したマウス培養骨格筋クローン細胞の樹立と機能解析
2018 - 2023 運動の恩恵効果が骨格筋から分泌されるマイオカインによって媒介されることの証明
2018 - 2023 運動の恩恵効果が骨格筋から分泌されるマイオカインによって媒介されることの証明
2018 - 2020 Role of muscle-specific insulin in prevention and formation of sarcopenia

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Papers (108)：

Teng Hu, Yasuro Furuichi, Yasuko Manabe, Kenichiro Yamada, Kengo Katakura, Yuna Aoki, Kun Tang, Takaomi Sakai, Nobuharu L Fujii. Myokine BDNF highly expressed in Type I fibers inhibits the differentiation of myotubes into Type II fibers. Molecular biology reports. 2024. 51. 1. 1143-1143
Yasuro Furuichi, Ayana Furutani, Kotaro Tamura, Yasuko Manabe, Nobuharu L Fujii. Lack of Musashi-2 induces type IIa fiber-dominated muscle atrophy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023. 37. 9. e23154
Yasuro Furuichi, Naoko Goto-Inoue, Saki Uchida, Shun Masuda, Yasuko Manabe, Nobuharu L. Fujii. Stable isotope-labeled carnitine reveals its rapid transport into muscle cells and acetylation during contraction. Heliyon. 2023. 9. 4. e15281-e15281
Hiroki Hamaguchi, Kitora Dohi, Takaomi Sakai, Masato Taoka, Toshiaki Isobe, Tsubasa S Matsui, Shinji Deguchi, Yasuro Furuichi, Nobuharu L Fujii, Yasuko Manabe. PDGF-B secreted from skeletal muscle enhances myoblast proliferation and myotube maturation via activation of the PDGFR signaling cascade. Biochemical and biophysical research communications. 2023. 639. 169-175
Hiroki Hamaguchi, Tsubasa S. Matsui, Shinji Deguchi, Yasuro Furuichi, Nobuharu L. Fujii, Yasuko Manabe. Establishment of a system evaluating the contractile force of electrically stimulated myotubes from wrinkles formed on elastic substrate. Scientific Reports. 2022. 12. 1

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MISC (179)：

三田佳貴, 藤井宣晴. 【スポーツと代謝~体力、瞬発力、疲労回復~】マイオカインによる運動機能の亢進. FOOD Style 21. 2023. 27. 5. 33-36
藤井宣晴, 三田佳貴. A goal to reach for myokine research. 実験医学. 2022. 40. 2
藤井宣晴. Shin・skeletal muscle world:<-Skeletal muscle research rises to a crescendo. 実験医学. 2022. 40. 2
古市泰郎, 三田佳貴, 眞鍋康子, 藤井宣晴. Symposium17-2. 体力科学. 2022. 71. 1
藤井宣晴, 古市泰郎, 眞鍋康子. Living under the same roof with excessive fat and reduced muscle: Sarcopenic obesity. 実験医学. 2021. 39. 5

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Patents (6)：

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Books (14)：

analysis of movement skill and evaluation of physical function
バイオメカニズム学会,慶應義塾大学出版会 (発売) 2023 ISBN:9784766429060
すべての診療科で役立つ身体運動学と運動療法
羊土社 2022 ISBN:9784758123884
運動処方の指針原書第10版
南江堂 2020
筋肉研究最前線
NTS 2019
筋肉のきほん : 筋肉をつけて健康的な体を手に入れよう!
ニュートンプレス 2019 ISBN:9784315521443

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Work history (6)：

2020/04 - 現在東京都立大学人間健康科学研究科ヘルスプロモーションサイエンス学域教授
2008/01 - 2020/03 Tokyo Metropolitan University
2001/04 - 2007/12 Harvard Medical School, Joslin Diabetes Center Instructor of Medicine (Harvard Medical School), Research Associate (Joslin Diabaetes Center)
1999/01 - 2001/03 Harvard University
1996/04 - 1998/12 University of Tsukuba Institute of Applied Biochemistry

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Awards (6)：

2022 - Bioscience, Biotechnology, and Biochemistry Best manuscript in 2022 Mass spectrometry imaging reveals local metabolic changes in skeletal muscle due to chronic training.
2006/07 - Federation of American Societies for Experimental Biology (FASEB) Travel Award
2001/04 - The Mary K. Iacocca Foundation Iacocca Research Fellowship
1999/04 - The Japan Society for the Promotion of Science Overseas Research Fellowships
1999/04 - The Uehara Memorial Foundation Fellowship for Research Abroad Refused

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Association Membership(s) (5)：

America Society for Biochemistry and Molecular Biology , American Diabetes Association , THE JAPANESE SOCIETY OF PHYSICAL FITNESS AND SPORTS MEDICINE , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , JAPAN SOCIETY FOR CELL BIOLOGY

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