TSUBOKO Yusuke

• 2024 - 2027 小児用医療機器実用化のための非臨床評価系構築に資する臨床データの利活用に関する研究
• 2024 - 2027 術中サージカルスモーク曝露の影響を定量する包括的評価系の確立
• 2023 - 2026 Prolonged ex vivo heart perfusion incorporating ventricular assist device to preserve the myocardial function
• 2023 - 2026 右心室組織ハイブリッド循環シミュレータを用いた新たな三尖弁治療デバイスの提案
• 2023 - 2024 外科術後のリンパ節検索の適正化を目的とした脂肪除去技術の研究開発
2021 - 2024 Development of decellularized small-diameter arterial grafts and evaluation in large animal experiments
2021 - 2024 経カテーテル的僧帽弁治療システムの開発
2021 - 2024 心外膜下脂肪量および脂肪肝に着目した虚血性心疾患予測のための機械学習モデルの構築
2021 - 2024 Development of an experimental method for measuring three-dimensional strain distribution in calcified coronary artery model during balloon expansion
2020 - 2023 Subsidy Program for Development of International Standards for Evaluation of Innovative Medical Devices and Regenerative Medicine Products
2020 - 2023 Creating a foundation to promote the development of advanced class IV medical devices by the development of human pathological simulator and system (HuPaSS)
2019 - 2022 Development of visualization method of stent thrmobosis in bifurcated coronary artery
2021 - 2022 Development of a novel arterial lesion vessel model for pulsatile cerebrovascular circulatory simulation
2021 - 2022 Development of a method for measuring three-dimensional vascular strain induced by endovascular medical devices
2021 - 2021 外科術後のリンパ節検索の適正化を目的とした脂肪除去技術の開発
2018 - 2021 Development of the small blood circulation simulator to deepen the non-clinical evaluation of medical devices
2018 - 2021 Establishment of a three-dimensional strain measurement method for the quantitative evaluation of transcatheter aortic valve deployment
2020 - 2021 Development of a method for measuring three-dimensional vascular strain induced by endovascular medical devices
2019 - 2020 Development of a method for measuring three-dimensional vascular strain induced by endovascular medical devices
2017 - 2020 Subsidy Program for Development of International Standards for Evaluation of Innovative Medical Devices and Regenerative Medicine Products
2018 - 2019 Mechanical Modeling of Pulmonary Vascular Resistance Based on Hemodynamic Masurements
2015 - 2017 医工学的方法論による小児用肺動脈弁の設計開発のためのシステム構築

• Jumpei Takada, Hayato Morimura, Kohei Hamada, Yusei Okamoto, Shiho Mineta, Yusuke Tsuboko, Kaoru Hattori, Kiyotaka Iwasaki. A tissue-silicone integrated simulator for right ventricular pulsatile circulation with severe functional tricuspid regurgitation. Scientific reports. 2024. 14. 1. 5120-5120
• Hideyuki Sakoda, Yusuke Tsuboko, Yoshihiro Okamoto, Eiichi Yamamoto, Takashi Imagama, Takashi Sakai, Hidetoshi Hamada, Nobuhiko Sugano. Lipid index to quantify the absorbed lipids in retrieved UHMWPE components of joint arthroplasty. Bio-medical materials and engineering. 2024
• Takayuki Okamura, Kiyotaka Iwasaki, Hongze Lu, Xiaodong Zhu, Tatsuhiro Fujimura, Norika Kitaba, Keisuke Murakami, Ryota Nakamura, Haruki Mitsui, Yusuke Tsuboko, et al. Importance of optimal rewiring guided by 3-dimensional optical frequency domain imaging during double-kissing culotte stenting demonstrated through a novel bench model. Scientific reports. 2023. 13. 1. 13511-13511
• Jumpei Takada, Kohei Hamada, Xiaodong Zhu, Yusuke Tsuboko, Kiyotaka Iwasaki. Biaxial tensile testing system for measuring mechanical properties of both sides of biological tissues. Journal of the mechanical behavior of biomedical materials. 2023. 146. 106028-106028
• 池田諒, 菊地千鶴男, 坪子侑佑, 池原大烈, 池原大烈, 渡邊冴基, 山田有希子, 市原有起, 浜崎安純, 岩崎清隆, et al. A Case of Redo-Mitral Valve Replacement for a Bjork-Shiley Delrin Valve Implanted 47 Years Previously. 日本心臓血管外科学会雑誌. 2023. 52. 1. 29-33

ｍore...

• 岡本 吉弘, 森脇 健司, 山家 弘雄, 坪子 侑佑, 迫田 秀行, 山本 栄一. コンプライアントバルーンから血管が受ける圧力の検討. 脳血管内治療. 2023. 8. Suppl. S822-S822
• 岡本吉弘, 森脇健司, 山家弘雄, 坪子侑佑, 迫田秀行, 山本栄一. コンプライアントバルーンから血管が受ける圧力の検討. 脳血管内治療(Web). 2023. 8. Supplement
• 坪子侑佑. 医工連携の成果を出すために何が必要か?-評価技術・試験法開発の観点から考える-. 医工学治療. 2023. 35. Supplement. 112-112
• 石川翔梧, 坪子侑佑, 岡本吉弘, 藤崎和弘, 森脇健司. フィルム型センサによる狭窄血管モデルとバルーンカテーテル間に作用する接触圧力の計測. 人工臓器(日本人工臓器学会). 2023. 52. 2. S-174
• 坪子侑佑, 植松美幸, 迫田秀行, 岡本吉弘, 山本栄一. 医療用マイクロニードルアレイの穿刺性評価に関する研究. 人工臓器(日本人工臓器学会). 2023. 52. 2. S-118

ｍore...

• 摘出組織処理装置、および摘出組織処理方法
• 摘出組織処理装置、および摘出組織処理方法
• 人工内臓ドライブラインモデルの皮膚癒着強度測定装置、人工内臓ドライブラインモデルの皮膚癒着強度判定方法
• 人工内臓ドライブラインモデルの皮膚癒着強度測定装置、人工内臓ドライブラインモデルの皮膚癒着強度判定方法
• 模擬心房を備える血液循環模擬装置、血液循環模擬装置を用いた人工臓器の試験方法

ｍore...

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  (39th Annual Meeting of the Japanese Society for Therapeutic Engineering 2023)
• 流れの可視化技術による血管内治療機器の非臨床試験法開発
  (脳神経血管内治療に関する医工学連携研究会 2023)
• 非臨床実験モデルを用いた補助循環治療の検討と臨床への応用
  (第50回人工心臓と補助循環懇話会学術集会 2022)
• 非臨床評価技術による人工心臓の開発促進
  (第50回人工心臓と補助循環懇話会学術集会 2022)
• 血管内補助循環デバイスの治療効果を可視化する粒子画像流速計測評価系の開発
  (第50回人工心臓と補助循環懇話会学術集会 2022)

ｍore...

• 2013 - 2016 Tohoku University Graduate School of Biomedical Engineering Doctoral Course
• 2011 - 2013 Tohoku University Graduate School of Biomedical Engineering Master's Course
• 2007 - 2011 Yamagata University Faculty of Engineering Department of Bio-system Engineering

• Ph.D. in Biomedical Engineering (Tohoku University)

• 2024/05 - 現在 National Institute of Health Sciences Division of Medical Devices Senior Researcher
• 2023/09 - 現在 Waseda University Department of Medern Mechanical Engineering, School of Creative Science and Engineering, Faculty of Science and Engineering Part-time Lecturer
• 2023/04 - 現在 Waseda University Comprehensive Research Organization Adjunct Researcher
• 2023/01 - 2024/04 National Institute of Health Sciences Division of Medical Devices Senior Researcher (without tenure)
• 2020/04 - 2023/03 Waseda University Department of Modern Mechanical Engineering, School of Creative Science and Engineering, Faculty of Science and Engineering Lecturer (Concurrent post)
2020/04 - 2022/12 Waseda University Institute for Medical Regulatory Science, Comprehensive Research Organization Member
2019/04 - 2022/12 Waseda University Waseda Research Institute for Science and Engineering Junior Researcher (Assistant Professor)
2018/04 - 2022/12 National Institute of Health Sciences Division of Medical Devices Collaborative Researcher
2021/04 - 2022/03 Tohoku University Institute of Fluid Science Collaborative Researcher
2020/05 - 2022/03 Tokyo University of Agriculture and Technology Faculty/Graduate School of Engineering Adjunct Lecturer
2019/04 - 2020/03 Waseda University Institute for Medical Regulatory Science, Organization for University Research Initiatives Member
2018/04 - 2019/03 Tohoku University PreClinical Research Center, Institute of Development, Aging and Cancer Collaborative Researcher
2017/06 - 2019/03 Waseda University Institute for Medical Regulatory Science Research Associate
2017/04 - 2017/05 Waseda University Institute for Medical Regulatory Science, Organization for University Research Initiatives Adjunct Researcher
2016/04 - 2017/03 Japan Society for the Promotion of Science JSPS Postdoctoral Research Fellow
2015/04 - 2016/03 Japan Society for the Promotion of Science JSPS Research Fellow (DC2)
2014/04 - 2015/03 Sendai College of Medical Health and Sports Department of Orthoptics Adjunct Lecturer
2013/04 - 2014/11 Institute of Development, Aging and Cancer, Tohoku University Department of Medical Engineering and Cardiology Research Assistant
2013/12 - 2014/03 Industrial Technology Institute, Miyagi Prefectural Government Material Development and Analysis Technology Department Intern

• 2023/06 - 現在 日本生体医工学会 若手研究者活動WG WG長
• 2023/05 - 現在 Japanese Society for Medical and Biological Engineering Councilor
• 2020/08 - 現在 Japanese Society for Medical and Biological Engineering Secretary
• 2020/05 - 現在 日本人工臓器学会 レギュラトリーサイエンス委員会 委員
• 2020/05 - 現在 日本人工臓器学会 医療産業促進委員会 委員
2019/04 - 現在 Japanese Society for Medical and Biological Engineering Committee member, Young Researcher's Working Group
2018/09 - 現在 Medical Technology Association of Japan (MT Japan) Committee member, ISO/TC 150 Japanese National Committee
2018/08 - 現在 Japanese Society for Medical and Biological Engineering Secretary, International Committee
2017/09 - 現在 International Organization for Standardization (ISO) Committee member, TC 150/SC 2/WG 1 (Cardiac valves)
2017/09 - 現在 International Organization for Standardization (ISO) Committee member, TC 150/SC 2/WG 3 (Vascular prostheses)
2017/05 - 現在 Japanese Society for Artificial Organs Council member
2019/10 - 2022/03 Japanese Society for Medical and Biological Engineering Committee member, Research award and the Abe award selection committee

• 2022/04 - 人工心臓と補助循環懇話会 若手研究者演題 最優秀賞 拍動循環シミュレータを用いたカテーテル軸流ポンプIMPELLAによる心機能補助性能評価に関する研究
• 2021/11 - 日本人工臓器学会 第59回日本人工臓器学会大会 大会賞優秀賞 断層粒子画像流速計測法を用いた大動脈解離モデルにおける解離進展の力学的機序解明に関する基礎検討
• 2020/11 - 日本人工臓器学会 第58回日本人工臓器学会大会 萌芽ポスターセッション優秀賞 粒子画像流速計測法による弾性左冠動脈前下行枝モデルの血行力学的解析
• 2020/05 - Japanese Society for Medeical and Biological Engineering 1st Prize, Young Investigator's Award Development of pulsatile circulatory system for measuring ascending aorta hemodynamics with 4D-MRI
• 2019/06 - Japanese Society of Biorheology Encouragement award
2018/06 - International Federation of Medical and Biological Engineering IFMBE Asia Pacific Research Networking Fellowship Sophisticated hydrodynamic simulation of pulmonary circulation for the preclinical examination of right heart circulatory assist device
2016/11 - 日本人工臓器学会 第54回日本人工臓器学会大会 萌芽ポスターセッション発表優秀賞 Fontan循環クリップ開発のための設計構成要素の基礎検討
2016/11 - Japanese Society for Artificial Organs Young Investigator Poster Award
2015/11 - Japanese Society for Artificial Organs Young Investigator Poster Award
2011/11 - Japanese Society for Artificial Organs Award Engineering analysis of the effects of bulging sinus in an newly designed paediatric pulmonary heart valve on hemodynamic function

Japanese Society for Cardiovascular Surgery ,  The Society of Life Support Engineering ,  THE JAPAN SOCIETY OF MECHANICAL ENGINEERS ,  Society for Regulatory Science of Medical Products ,  JAPANESE SOCIETY FOR MEDICAL AND BIOLOGICAL ENGINEERING ,  JAPANESE SOCIETY FOR ARTIFICIAL ORGANS ,  Japanese Society of Biorheology ,  JAPANESE ASSOCIATION OF CARDIOVASCULAR INTERVENTION AND THERAPEUTICS ,  THE VISUALIZATION SOCIETY OF JAPAN ,  THE INSTITUTE OF ELECTRICAL AND ELECTRONIC ENGINEERS ,  JAPANESE SOCIETY OF VETERINARY CARDIOLOGY