Research keywords (4)：
Inter-individual variability
, Drug metabolizing enzymes
, Toxicology
, Drug metabolism
Research theme for competitive and other funds (1)：
2019 - 2021 Characterization of human glutathione S-transferase P1-1-catalyzed glutathionylation of proteins: as a clue to understand the inter-individual difference in drug-induced toxicity
den Braver-Sewradj SP, den Braver MW, Toorneman RM, van Leeuwen S, Zhang Y, Dekker SJ, Vermeulen NPE, Commandeur JNM, Vos JC. Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations. Chemical research in toxicology. 2018. 31. 2. 116-126
ZHANG, Yongjie. In vitro and cellular systems for the characterization of bioactivating and inactivating drug metabolizing enzymes in adverse drug reactions: Insights into amodiaquine idiosyncratic toxicity. Vrije Universiteit Amsterdam. 2018
Evaluation of the protective effects of glutathione S-transferase P1 against the cytotoxicity of amodiaquine quinoneimine in HepG2 cells
(2017 FIGON Dutch Medicine Days 2017)
Education (1)：
2013 - 2017 VU University Amsterdam Molecular and Computational Toxicology
Association Membership(s) (1)：
International Society for the Study of Xenobiotics
