Rchr
J-GLOBAL ID:201801006529192874   Update date: Aug. 24, 2024

Atsuhiko Naito

ナイトウ アツヒコ | Atsuhiko Naito
Affiliation and department:
Homepage URL  (1): https://www.toho-u.ac.jp/med/lab/lab_cytophysiology.html
Research field  (4): Cell biology ,  Cardiology ,  Physiology ,  Pharmacology
Research keywords  (9): 心筋細胞 ,  心不全 ,  発生・分化 ,  老化 ,  DNA損傷 ,  iPS細胞 ,  安全性薬理 ,  創薬 ,  心臓発生
Research theme for competitive and other funds  (6):
  • 2019 - 2023 心筋細胞特有のゲノムDNA損傷応答機構の解明
  • 2014 - 2017 Epigenome analysis in cardiomyocyte differentiation and failure
  • 2014 - 2016 Development of a System to Obtain Mature Ventricular Cardiomyocytes from Human induced Pluripotent Stem cells
  • 2011 - 2014 The role of C1q and Wnt signaling in aging and diabetes
  • 2011 - 2013 What is the physiological role of cardiac stem cells ?
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Papers (35):
  • 沼田 玄理, 瀧本 英樹, 大津 裕, 豊田 真之, 内藤 篤彦, 小室 一成. Role of Beta 1 Adrenergic Receptor in Acute Heart Failure: Analysis of Cardiomyocyte-Specific Knockout of Beta 1 Adrenergic Receptor(タイトル和訳中). 日本循環器学会学術集会抄録集. 2023. 87回. OJ61-3
  • Nobuyuki Suzuki, Ryuichi Kambayashi, Ai Goto, Hiroko Izumi-Nakaseko, Yoshinori Takei, Atsuhiko T Naito, Atsushi Sugiyama. Cardiovascular safety pharmacology of ivermectin assessed using the isoflurane-anesthetized beagle dogs: ICH S7B follow-up study. The Journal of toxicological sciences. 2023. 48. 12. 645-654
  • Shigeyuki Magi, Sewon Ki, Masao Ukai, Elisa Domínguez-Hüttinger, Atsuhiko T Naito, Yutaka Suzuki, Mariko Okada. A combination approach of pseudotime analysis and mathematical modeling for understanding drug-resistant mechanisms. Scientific reports. 2021. 11. 1. 18511-18511
  • Hideki Yasutake, Jong-Kook Lee, Akihito Hashimoto, Kiyoshi Masuyama, Jun Li, Yuki Kuramoto, Shuichiro Higo, Shungo Hikoso, Kyoko Hidaka, Atsuhiko T Naito, et al. Decreased YAP activity reduces proliferative ability in human induced pluripotent stem cell of duchenne muscular dystrophy derived cardiomyocytes. Scientific reports. 2021. 11. 1. 10351-10351
  • Shigeyuki Magi, Sewon Ki, Masao Ukai, Atsuhiko Naito, Yutaka Suzuki, Mariko Okada. Mathematical Modeling and Transcriptome Profiling of Breast Cancer Cells During Tamoxifen Treatment Reveal Multiple Trajectories for Resistant Subtypes. 2021
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MISC (124):
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Patents (2):
Lectures and oral presentations  (18):
  • Pathogenic role of DNA single-strand break accumulation and DNA damage response in pressure overload-induced heart failure.
    (WCP2018 2018)
  • Assessment of the drug-induced cardiac functional toxicity by pattern-cultured hiPSC-CMs.
    (WCP2018 2018)
  • TRPC3 Inhibitor Pyr3 Corrects the Disease-specific Phenotype of the Induced Pluripotent Stem Cell-derived Cardiomyocytes from the Patients with Infantile Hypertrophic Cardiomyopathy.
    (WCP2018 2018)
  • Assessment of the drug-induced toxicity against left ventricular function by pattern-cultured hiPSC-CMs.
    (Safety Pharmacology Science Annual Meeting 2018)
  • ヒトiPS細胞由来心筋細胞を利用した医薬品の安全性評価
    (第22回日本心血管内分泌代謝学会 2018)
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Professional career (1):
  • 博士(医学) (千葉大学)
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