Rchr
J-GLOBAL ID：201801010026608450   Update date: Jul. 25, 2024

Otaki Hiroki

オオタキ ヒロキ | Otaki Hiroki
Affiliation and department：
長崎大学 医歯薬学総合研究科(医学系)

About 長崎大学 医歯薬学総合研究科(医学系)


Job title： 助教
Research field  (4)： Biophysics ,  Pharmaceuticals - chemistry and drug development ,  Bio-, chemical, and soft-matter physics ,  Basic physical chemistry
Research keywords  (4)： 化学物理 ,  生物物理 ,  計算化学 ,  量子化学
Papers (28)：
  • Hiroki Otaki, Shun-ichi Ishiuchi, Masaaki Fujii, Yuji Sugita, Kiyoshi Yagi. Similarity scores of vibrational spectra reveal the atomistic structure of pentapeptides in multiple basins. Physical Chemistry Chemical Physics. 2024. 26. 13. 9906-9914
  • Hiroki Otaki, Shun-ichi Ishiuchi, Masaaki Fujii, Yuji Sugita, Kiyoshi Yagi. Similarity scores of vibrational spectra reveal the atomistic structure of pentapeptides in multiple basins. ChemRxiv. 2023. 10.26434/chemrxiv-2023-qn9rc
  • Toshihide Maki, Zheyang Zhou, Yukari Irie, Takahide Matsunaga, Takae Onodera, Shoji Imamichi, Yuka Sasaki, Mitsuko Masutani, Hiroki Otaki, Eri Sakuda, et al. Singlet-oxygen photosensitizers with a tetrad structure and a single BODIPY chromophore: An evidence for transition state stabilization of intersystem crossing. Dyes and Pigments. 2022. 210. 110963-110963
  • Hiroki Otaki, Yuzuru Taguchi, Noriyuki Nishida. Conformation-Dependent Influences of Hydrophobic Amino Acids in Two In-Register Parallel β-Sheet Amyloids, an α-Synuclein Amyloid and a Local Structural Model of PrPSc. ACS Omega. 2022. 7. 35. 31271-31288
  • Satoshi Mizuta, Hiroki Otaki, Takeshi Ishikawa, Juliann Nzembi Makau, Tomoko Yamaguchi, Takuya Fujimoto, Nobuyuki Takakura, Nobuki Sakauchi, Shuji Kitamura, Hikaru Nono, et al. Lead Optimization of Influenza Virus RNA Polymerase Inhibitors Targeting PA-PB1 Interaction. Journal of Medicinal Chemistry. 2022. 65. 1. 369-385
ｍore...
MISC (11)：
  • 大滝大樹. 分子動力学計算を用いたDNA分解酵素の失活メカニズムの解明. スーパーコンピューティングニュース. 2024. 26. 2. 47-51
  • 大滝大樹. 分子動力学計算によるアミロイド凝集様態の理論的解析. スーパーコンピューティングニュース. 2022. 24. 3. 81-87
  • 大滝大樹. 分子動力学シミュレーションによる自己炎症性疾患に関わるタンパク質の研究. スーパーコンピューティングニュース. 2021. 23. 特集号1. 28-34
  • 水田賢志, 大滝大樹, 渡邊健. Design and synthesis of quinolinone derivatives which inhibit influenza virus RNA polymerase. 日本薬学会年会要旨集(Web). 2021. 141st
  • 水田賢志, 大滝大樹, 渡邊健. Drug discovery of anti-influenza viral RNA-dependent RNA polymerase agents by targeting the PA-PB1 interaction. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
ｍore...
Patents (5)：
Books (1)：
  • Molecular Spectroscopy: A Quantum Chemistry Approach
    Wiley-VCH 2019 ISBN:9783527344611
Lectures and oral presentations  (77)：
  • Designing cyclic peptides to inhibit pathogenic amyloid conversion in human prion diseases as potential therapeutic agents
    (2024)
  • Interaction analysis of DNA exonuclease mutants using molecular dynamics simulations and residue interaction network
    (2023)
  • 分子動力学計算とネットワークグラフを用いたDNA分解酵素における変異の影響の解析
    (第36回分子シミュレーション討論会 2022)
  • 分子動力学計算とネットワーク解析を用いたDNA分解酵素における変異の影響の解析
    (第128回日本物理学会九州支部例会 2022)
  • Molecular dynamics study of the three prime repair exonuclease 1 and its mutants
    (The 60th Annual Meeting of the Biophysical Society of Japan 2022)
ｍore...
Education (4)：
  • 2013 - Kyoto University
  • 2009 - 2012 Kyoto University Graduate School of Science Department of Chemistry
  • 2005 - 2007 Kyoto University Graduate School of Science Department of Chemistry
  • 2001 - 2005 Kyoto University
Professional career (1)：
  • 博士(理学) (京都大学)
Work history (7)：
  • 2023/04 - 現在 Nagasaki University School of Pharmaceutical Sciences
  • 2015/07 - 現在 Nagasaki University Graduate School of Biomedical Sciences Assistant Professor
  • 2015/07 - 2024/03 RIKEN Visiting Researcher
  • 2015/04 - 2015/06 RIKEN Postdoctral Reseacher
  • 2013/04 - 2015/03 Kogakuin University
Show all
Awards (2)：
  • 2012/02 - 2012 NTHU-KAIST-KYOTO Junior Chemist Symposium Best PowerPoint Presentation Award
  • 2011/10 - 分子科学会 第5回分子科学討論会 分子科学会優秀ポスター賞
Association Membership(s) (6)：
THE PHYSICAL SOCIETY OF JAPAN ,  JAPAN SOCIETY FOR MOLECULAR SCIENCE ,  分子シミュレーション学会 ,  日本蛋白質科学会 ,  CBI学会 ,  THE BIOPHYSICAL SOCIETY OF JAPAN
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM