Fujisato Toshia

フジサトトシヤ | Fujisato Toshia

Affiliation and department：
Job title： Professor
Research theme for competitive and other funds (25)：

2023 - 2028 ヒト骨格筋オルガノイドを活用した低酸素依存性マイオカインの網羅的探索と評価
2023 - 2026 包括的力学環境制御に基づく3次元筋疾患モデルの創生と薬効評価への応用
2020 - 2023 Tissue-engineered skeletal muscle for myokine secretion
2020 - 2023 三次元培養筋におけるコレシストキニン遺伝子発現制御および分泌動態の解明
2017 - 2020 Elucidation of a new physiological function of skeletal muscle utilizing a three-dimensional culture muscle

2016 - 2020 Tissue-engineered skeletal muscle and its application to actuator

2015 - 2018 Fabrication and evaluation of animal fiber originated nanofibers

2013 - 2016 Comprehensive analysis of gene expression induced by muscle contraction in three-dimensional tissue-engineered muscle.

2012 - 2016 Tissue-engineered skeletal muscle

2012 - 2015 Novel neointima-inducing treatment of acellular small-diameter blood vessel for good patency

2012 - 2014 Preparation of the acellular dermal matrix from the skin of giant melanocytic nevi

2008 - 2010 Development of a novel hybrid-acellular nerve graft using hypertonic sodium chloride solution

2006 - 2009 In vivo pretreatment of bio-derived and synthetic for cardiovascular tissue regeneration.

2007 - 2008 移植血管組織の石灰化に関する研究

2007 - 2008 脱細胞血管をスキャフォールドとした小口径人工血管モデルの作製

2003 - 2005 Induction of transplantation tolerance by co-transplantation of vascularized thymic lobe in miniature swine

2002 - 2005 Development of Biological Scaffolds for Pediatric Patients having Growth Potential

2000 - 2002 DEVELOPMENT OF ARTIFICIAL TISSUE SCAFFOLD FOR ISLET CELL TRANSPLANTATION

1997 - 1999 Basic research for mini-pig production to induction og human MHC genes

1997 - 1999 家畜動物体内での自家移植用ヒト組織の作出

1996 - 1998 STUDY ON REAL-TIME MEASUREMENT OF CARDIAC MUSCLE VISCOELASTICITY USING AN ULTRASONIC TACTILE MICROSENSOR CATHETER

1996 - 1998 DEVELOPMENT OF THE SYSTEM FOR CREATING A TRANSGENIC MINIPIG WITH THE THREE-DIMENSIONAL MONITORING SYSTEM

1996 - 1998 Development of New Circulatory Assist Device-Split-Circulation Assits Device

1995 - 1997 Afferent Reinnervation After Lung Transplantation in the Rat

1995 - 1995 心臓ペーシング用神経接続材料に関する基礎研究

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Papers (119)：

Dong Yi, Takeshi Sugimoto, Teppei Matsumura, Sho Yokoyama, Toshia Fujisato, Tomohiro Nakamura, Takeshi Hashimoto. Investigating the Combined Effects of Mechanical Stress and Nutrition on Muscle Hypertrophic Signals Using Contractile 3D-Engineered Muscle (3D-EM). Nutrients. 2023. 15. 18
Kota KISHISHITA, Tomohiro NAKAMURA, Marino MIZUTANI, Toshia FUJISATO, Takeshi HASHIMOTO, Naoko MATSUI, Hiroko MARUKI-UCHIDA, Naoki IEMOTO, Sho YOKOYAMA. Novel platform for quantitative evaluation of medicinal efficacy based on contractility of artificial skeletal muscle. Journal of Biomechanical Science and Engineering. 2023. 18. 4. 23-00396
Takeshi Sugimoto, Shoma Imai, Maki Yoshikawa, Toshia Fujisato, Takeshi Hashimoto, Tomohiro Nakamura. Mechanical unloading of 3D-engineered muscle leads to muscle atrophy by suppressing protein synthesis. Journal of Applied Physiology. 2022. 132. 4. 1091-1103
Tomohiro Nakamura, Shunya Takagi, Daisuke Okuzaki, Seika Matsui, Toshia Fujisato. Hypoxia transactivates cholecystokinin gene expression in 3D-engineered muscle. Journal of Bioscience and Bioengineering. 2021. 132. 1. 64-70
Mako Kobayashi, Masako Ohara, Yoshihide Hashimoto, Naoko Nakamura, Toshiya Fujisato, Tsuyoshi Kimurai, Akio Kishidai. Effect of luminal surface structure of decellularized aorta on thrombus formation and cell behavior. PLoS ONE. 2021. 16. 5 May 2021

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MISC (622)：

中村友浩, 藤里俊哉. Cck gene expression in 3D-engineered muscle and the hypoxia response. 月刊細胞. 2022. 54. 7
藤里俊哉. Tissue-engineered Skeletal Muscle. 化学工業. 2021. 72. 5
小林真子, 小原雅子, 橋本良秀, 中村奈緒子, 藤里俊哉, 木村剛, 岸田晶夫. 脱細胞化血管の内腔表面が及ぼす血栓形成と内皮化への影響. 日本再生医療学会総会(Web). 2021. 20th
杉本岳史, 中村友浩, 横山奨, 藤里俊哉, 小西聡, 橋本健志. Investigation of brain function-related myokines secretion by using contractile 3D-engineered skeletal muscle. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
岸田晶夫, 田中雄也, 藤里俊哉, 澤田和也. Supercritical Fluid Extraction of Biological Tissue and Its Application to Tissue Engineering. 生体医歯工学共同研究拠点成果報告書. 2020. 2019

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Patents (13)：

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