Rchr
J-GLOBAL ID：202301007490874219
Update date: Jun. 19, 2024
Wada Mikako
ワダ ミカコ | Wada Mikako
Affiliation and department：
Job title：
Project Researcher
Research keywords (5)：
遺伝子治療
, アデノ随伴ウイルスベクター
, アデノウイルスベクター
, 性分化
, アフリカツメガエル
Research theme for competitive and other funds (3)：
- 2021 - 2024 Development of a hematopoietic stem cell-targeted lentiviral vector system
- 2018 - 2020 Genome-editing in hematopoietic cells with all-in-one HDAdV-CRISPR
- 2010 - 2015 sex differences regulated by W- and Y-sex chromosomes
Papers (8)：
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Makusu Tsutsui, Mikako Wada, Akihide Arima, Yuji Tsunekawa, Takako Sasaki, Kenji Sakamoto, Kazumichi Yokota, Yoshinobu Baba, Tomoji Kawai, Takashi Okada. Identifying Viral Vector Characteristics by Nanopore Sensing. ACS nano. 2024
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Yae Kurosawa, Yuji Tsunekawa, Mikako Wada, Yuko Aizen, Yuko Nitahara-Kasahara, Takashi Okada. Purification of Adeno-Associated Viral Vector Serotype 9 Using Ceramic Hydroxyapatite Chromatography and its Analysis. Current protocols. 2024. 4. 6. e1068
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Rimi Miyaoka, Yuji Tsunekawa, Yae Kurosawa, Takako Sasaki, Azusa Onodera, Kenji Sakamoto, Yuko Kakiuchi, Mikako Wada, Yuko Nitahara-Kasahara, Hiromi Hayashita-Kinoh, et al. Development of a novel purification method for AAV vectors using tangential flow filtration. Biotechnology and bioengineering. 2023
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Mikako Wada, Naoya Uchida, Guillermo Posadas-Herrera, Hiromi Hayashita-Kinoh, Yuji Tsunekawa, Yukihiko Hirai, Takashi Okada. Large-scale purification of functional AAV particles packaging the full genome using short-term ultracentrifugation with a zonal rotor. Gene therapy. 2023. 30. 7-8. 641-648
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Shuuji Mawaribuchi, Shuji Takahashi, Mikako Wada, Yoshinobu Uno, Yoichi Matsuda, Mariko Kondo, Akimasa Fukui, Nobuhiko Takamatsu, Masanori Taira, Michihiko Ito. Sex chromosome differentiation and the W- and Z-specific loci in Xenopus laevis. Developmental biology. 2017. 426. 2. 393-400
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MISC (6)：
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和田美加子, 岡田尚巳. GMP Manufacturing for AAV Therapeutics. 医学のあゆみ. 2023. 285. 5. 317-320
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和田美加子, 奥島菜々子, 新田洋久, 岩長ゆずる, 早乙女彩, 栗原佳絵, 海老原康博, 三谷幸之介. CRISPR/Cas9による遺伝子修復治療法の確立に向けたSCID-X1モデルマーモセット造血幹前駆細胞でのゲノム編集. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
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和田美加子, 藤谷和子, 回渕修治, 田村啓, 高松信彦, 伊藤道彦. ツメガエル初期生殖巣形成におけるmass-in-line構造の雌雄化機構. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th
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岡野則仁, 藤谷和子, 田村啓, 荻田悠作, 和田美加子, 高松信彦, 伊藤道彦. 生殖細胞運命・雄化に関わる転写因子DMRT1の天然変性領域とオーダー領域による転写活性化領域の分子進化. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th
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回渕 修治, 和田 美加子, 高橋 秀治, 宇野 好宣, 松田 洋一, 近藤 真理子, 福井 彰雅, 高松 信彦, 平良 眞規, 伊藤 道彦. Xenopus laevis全ゲノム解析 アフリカツメガエルの性染色体とWおよびZ特異的領域の解析. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [1P0563]-[1P0563]
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Lectures and oral presentations (17)：
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Short-term and large-scale production of high-quality recombinant adeno-associated virus using a zonal ultracentrifugation
(2024)
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大規模製造に向けたゾーナル超遠心による 短時間高精度組換えアデノ随伴ウイルスベクター精製法の開発
(The 29th Annual Meeting of Japan Society of Gene and Cell Therapy 2023)
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GMP viral vector manufacturing for academia R&D
(The 29th Annual Meeting of Japan Society of Gene and Cell Therapy 2023)
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Large-scale production of high-quality recombinant adeno-associated virus using short-term zonal ultracentrifugation
(American Society of Gene & Cell Therapy 26th Annual Meeting 2023)
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大規模製造に向けたゾーナル超遠心による 短時間高精度組換えアデノ随伴ウイルスベクター精製法の開発
(The 28th Annual Meeting of Japan Society of Gene and Cell Therapy 2022)
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Education (2)：
- 2012 - 2017 Kitasato University Graduate School of Science
- 2008 - 2012 Kitasato University School of Science Department of Biological Sciences
Work history (1)：
- 2017/04 - 2020/03 Saitama Medical University Research Center for Genomic Medicine Division of Gene Therapy
Awards (1)：
- 2024/05 - American Society of Gene & Cell Therapy's 27th Annual Meeting MERITORIOUS ABSTRACT TRAVEL AWARD
Association Membership(s) (1)：
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