Rchr
J-GLOBAL ID：200901009451066701
Update date: Oct. 31, 2024
Mikawa Tsutomu
ミカワ ツトム | Mikawa Tsutomu
Affiliation and department：
Job title：
Senior Research Scientist
Other affiliations (2)：
Homepage URL (2)：
https://www2.riken.jp/bio-spra/mikawa/mikawa.html
,
https://www2.riken.jp/bio-spra/mikawa/mikawa_e.html
Research field (4)：
Structural biochemistry
, Biophysics
, Genetics
, Functional biochemistry
Research keywords (7)：
LLPS
, biofuel cell
, enzyme
, protein
, recombination
, RecA
, DNA repair
Research theme for competitive and other funds (19)：
- 2021 - 2024 発汗成分モニタリングのためのウェアラブルセンサの創成と熱中症との相関解析
- 2021 - 2024 In-situ structural biology by NMR spectroscopy
- 2015 - 2020 バイオ燃料電池を搭載したウェアラブルヘルスケアデバイスの創成
- 2015 - 2018 In-organelle NMRによるミトコンドリア内蛋白質の動態解析
- 2015 - 2018 酵素反応多段階化によるバイオ燃料電池の飛躍的高容量化
- 2016 - 2017 無細胞DNA組換え系を用いた人工蛋白質創製技術の確立
- 2013 - 2016 バイオ燃料電池の飛躍的高出力化
- 2010 - 2015 Toward manual control of the initiation of homologous recombination for genome diversification
- 2013 - 2015 バイオ燃料電池の高出力・高容量化
- 2009 - 2014 Functions of intrinsically disordered regions in homologous recombination
- 2010 - 2012 A regulation mechanism of homologous recombination by protein-protein interactions
- 2009 - 2011 A novel technique producing hybrid proteins by using homologous recombination in vitro
- 2007 - 2009 Molecular mechanism for the accurate recognition of homologous sequences
- 2006 - 2007 相同DNA対合活性を利用した高精度マルチプレックスPCR法の確立
- 2005 - 2006 Basic mechanisms of homologous pairing proteins
- 2004 - 2005 DNA相同組換えの制御機構に関わる蛋白質群の構造と機能
- 2002 - 2003 染色体相同組換えの制御機構に関わる蛋白質群の構造と機能
- 2000 - 2001 RecAファミリー蛋白質によるDNA組換え反応の分子機構の解析
- 1998 - 1998 高度好熱菌RecA蛋白質を用いたDNA組換え反応機構の解析
Show all
Papers (71)：
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Bowen Zhang, Bingfu Liu, Zhouji Wu, Kazuhiro Oyama, Masaomi Ikari, Hiromasa Yagi, Naoya Tochio, Takanori Kigawa, Tsutomu Mikawa, Takeo Miyake. A Hybrid Nanotube Stamp System in Intracellular Protein Delivery for Cancer Treatment and NMR Analytical Techniques. Analytical chemistry. 2024. 96. 21. 8349-8355
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Keita Tateno, Takami Ando, Maako Tabata, Haruka Sugasawa, Toshifumi Hayashi, PM Sayeesh, Kohsuke Inomata, Tsutomu Mikawa, Yutaka Ito, Teppei Ikeya. Different molecular recognition by three domains of the full-length GRB2 to SOS1 proline-rich motifs and EGFR phosphorylated sites. 2024
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Axelle Renodon-Corniere, Tsutomu Mikawa, Naoyuki Kuwabara, Kentaro Ito, Dmitri Levitsky, Hiroshi Iwasaki, Masayuki Takahashi. Human Rad51 Protein Requires Higher Concentrations of Calcium Ions for D-loop Formation Than for Oligonucleotide Strand Exchange. International journal of molecular sciences. 2024. 25. 7
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Keita Tateno, Takami Ando, Maako Tabata, Haruka Sugasawa, Toshifumi Hayashi, Sangya Yu, Sayeesh PM, Kohsuke Inomata, Tsutomu Mikawa, Yutaka Ito, et al. Different molecular recognition by three domains of the full-length GRB2 to SOS1 proline-rich motifs and EGFR phosphorylated sites. Chemical Science. 2024
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Isao Shitanda, Taisei Oshimoto, Noya Loew, Masahiro Motosuke, Hikari Watanabe, Tsutomu Mikawa, Masayuki Itagaki. Biosensor development for low-level acetaldehyde gas detection using mesoporous carbon electrode printed on a porous polyimide film. Biosensors & bioelectronics. 2023. 238. 115555-115555
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MISC (21)：
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URA Tomoto, URA Tomoto, URA Tomoto, TOMITA Shunsuke, SAKAKIBARA Nanako, SAKAKIBARA Nanako, YAGI Hiromasa, TOCHIO Naoya, KIGAWA Takanori, MIKAWA Tsutomu, et al. In vitro construction of enzyme assemblies by liquid-liquid phase separation. 日本蛋白質科学会年会プログラム・要旨集. 2023. 23rd (CD-ROM)
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田端真彩子, 池谷鉄兵, 美川務, 川端庸平, 安藤考史, 館野桂太, 三島正規, 伊藤隆. Structural analysis of a multi-domain protein Grb2 using PRE and PCS restraints. Abstracts. Annual Meeting of the NMR Society of Japan. 2020. 59th
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清水涼香, 美川務, 福嶋瑞穂, 池谷鉄兵, 池谷鉄兵, 鴨志田一, 木川隆則, 三島正規, 伊藤隆, 伊藤隆. NMRによる蛋白質のミトコンドリア内動態の解析. Abstracts. Annual Meeting of the NMR Society of Japan. 2018. 57th
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井上仁, 井上仁, 永江峰幸, 三島正規, 伊藤隆, 柴田武彦, 柴田武彦, 美川務, 美川務, 美川務. 蛋白質間相互作用により生じる単鎖DNA結合蛋白質(SSB/RPA)のssDNAからの解離の一般的機構. 日本蛋白質科学会年会プログラム・要旨集. 2011. 11th
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井上仁, 井上仁, 永江峰幸, 三島正規, 伊藤隆, 柴田武彦, 柴田武彦, 美川務, 美川務, 美川務. ssDNA上でのSSBの置換におけるSSB-蛋白質相互作用の役割. 生化学. 2010
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Patents (21)：
Education (2)：
- 1994 - 1999 Osaka University Graduate School of Science Department of Biological Science
- 1990 - 1994 Osaka University Faculty of Science Department of Biology
Professional career (1)：
Work history (4)：
- 2008/04 - 現在 RIKEN Senior Research Scientist
- 2000/04 - 2008/03 RIKEN Research Scientist
- 1999/04 - 2000/03 RIKEN Special Postdoctoral Researcher
- 1996/04 - 1999/03 Research Fellow of the Japan Society for the Promotion of Science
Association Membership(s) (5)：
The Protein Society
, American Society for Biochemistry and Molecular Biology
, 日本蛋白質科学会
, 日本分子生物学会
, 日本生化学会
