Miyawaki Shouichi

2019 - 2022 胃内と口腔内の常在細菌叢、ブラキシズム及び胃食道逆流との関連性の解明

2019 - 2022 ストレスが食道の知覚過敏と覚醒時ブラキシズムに及ぼす影響の解明

2019 - 2022 炎症性メディエーターの動態が食道知覚の変化とブラキシズムの発症に与える影響の解明

2018 - 2021 脳腸ペプチドによるストレス起因性顎口腔機能異常の改善に対する効果の検証

2018 - 2021 脳腸モデルによる迷走神経の活性化を応用したブラキシズムの根本療法開発への基盤研究

2018 - 2021 食道内の酸クリアランス促進によりブラキシズムを抑制する経皮的刺激療法の開発

2017 - 2020 マルチセンターリサーチによる日中覚醒時ブラキシズムの診断基準確立への挑戦

2017 - 2020 カリウムイオン競合型アシッドブロッカーを応用したブラキシズムの根本療法の開発

2017 - 2020 自動埋入型骨固定装置による顎骨の成長促進が小児の睡眠呼吸障害に及ぼす効果の検討

2017 - 2020 消化管運動促進薬とH2ブロッカーによる咀嚼筋障害に対する治療効果の検討

2016 - 2020 不正咬合に起因する“顎口腔サルコペニア”の実態と内分泌・免疫系因子との関連

2015 - 2019 Investigation of effectiveness that surgical orthodontics for orofacial hypogrowth affect sleep apnea and gastroesophageal reflux

2015 - 2018 Effects of treatment of functional dyspepsia according to gene polymorphism on bruxism

2015 - 2018 Elucidation of the relationship between the stress adjustment and the stomatognathic function by the hypothalamic-pituitary-adrenal axis and the brain-gut interactions

2015 - 2018 Evaluation of a Proton Pump Inhibitor for Sleep Bruxism

2015 - 2018 Elucidation of the effect of orthodontic treatment in growing patients on sleep apnea, gastroesophageal reflux disease and respiratory disease

2014 - 2018 The brain function relationship among migraine, gastrointestinal disease and TMD

2014 - 2017 the development of orthopedic appliance combined with newly designed orthodontic anchor screw

2013 - 2017 Development of fundamental therapy for temporomandibular muscle disorders by gastroenterological approach.

2015 - 2017 遺伝子多型に応じた機能性ディスペプシアの治療がブラキシズムに及ぼす効果の解明

2015 - 2016 成長期の矯正治療が睡眠時無呼吸、胃食道逆流及び呼吸器疾患に及ぼす効果の解明

2013 - 2015 Evaluation of hypothesis which a malocclusion is caused by perception disorder and hypokinesia of pharynx, esophagus and stomach

2012 - 2015 The association between stmatognathic function and the sensation of the stomach and esophagus via brain activity

2012 - 2015 The study of the mechanism of the stomatognathic function activated by the brain and the gastrointestinal peptide

2012 - 2015 Influence of autonomic nervous activity and gastrointestinal hormones on regulation of gastric activity by mastication

2012 - 2015 Development of a skeletal anchorage system excluded all factors of failure

2013 - 2014 咽頭・食道・胃の知覚異常と運動機能の低下が不正咬合を引き起こす仮説の検証

2012 - 2014 脳-腸相関を軸とした顎口腔と胃食道との間の知覚-運動制御機構と関連疾患の解明

2012 - 2013 コミュニケーションツールが青少年の睡眠、消化器疾患および顎発育に及ぼす影響の解明

2011 - 2013 Cerebral activation and the mechanism when esophageal sensation causes awake bruxism

2011 - 2013 Development and treatment neurophysiological elucidation of the mechanism by bruxism-induced esophageal mucous membrane irritation

2011 - 2013 The effect of the sensitivity in the esophagus mucous on a parafunction of the stomatognathic system

2011 - 2013 Elucidation of the effects of periodontal pathogenic factor and excessive mechanical stress on signaling pathway of orthodontic tooth movement

2010 - 2011 Influence of gastric motility on sleep bruxism

2009 - 2011 Influence of experimental stimulation to nucleus and viscus on Sleep Bruxism

2009 - 2011 Effects of combined fixed functional appliances and skeletal anchorage in use on true mandibular growth in rats

2009 - 2011 Investigation of stretch-induced intracellular signal transduction in human periodontal ligament fibroblasts exposed to periodontopathic factors.

2009 - 2011 Relationships among pediatric sleep problems, problem behavior, gastroesophageal reflux and oral parafunctions

2008 - 2011 Influences of the occlusion on gastroesophageal reflux disease and acid clearance in oral cavity, pharynx and esophagus during sleep

2008 - 2010 Elucidation of the mechanism to trigger brux like movement in gastric-esophageal acid reflux model

2008 - 2010 Clarification of inflammatory reaction of orthodontic tooth movement in MyD88 knockout mice

2008 - 2010 Role of Ten-m/Odz3 in the formation, growth and functional maintenance of mandibular condylar cartilage

2008 - 2010 Influence of Duodeno-Gastro-Esophageal Reflux on Sleep Bruxism

2007 - 2008 Relationships among sleep disorders, sleep bruxism, psychological stress, respiratory and gastroesophageal symptoms and maxillofacial morphology in children

2006 - 2007 Effect of orthodontic implants on maxillary protrusive patients in a growth period

2006 - 2007 Electrophysiological histological study on the damage and adaptation to the masseter muscle by overactivity in the rat

2006 - 2007 The effect of antianxiety agent, saliva stimulant and gastric antisecretory activity on brux-like activity in rats

2006 - 2007 Effect of Helicobacter pylori eradication on sleep bruxism, periodontal disease and oral malodor

2006 - 2007 Clarification of relationship among psychological stress, gastro-oesophageal reflux, sleep bruxism, and salivary flow

2006 - 2007 The effect of salivator and acid suppressive drug on bruxism-related oral disease)

2006 - 2007 MRIの磁化移動効果を応用した咀嚼筋疲労の新しい定量評価法の確立

2005 - 2006 Gastroenterological study to reveal the occlusal splint therapy mechanism in patients with bruxism

2003 - 2004 Prospective cohort study to reveal the cause and effect relationship between sleep bruxism and temporomandibular disorders by recording biosignals.

2003 - 2004 Neurophysiological study to reveal the relationship between sleep bruxism and gastroesophageal reflux (GER).

2004 - Study to reveal the relationship between sleep bruxism and infection of H. P.

2002 - 2003 Development of system to predict oral and maxillofacial function after orthodontic treatment

2001 - 2002 The Kinematological and Biological Study to reveal the cause of Ostheoarthrosis of TMJ

2000 - 2001 Development of the model to calculate the mechanical stress which applied to the region of TMJ during functional jaw movement

2001 - Study to reveal the relationship between sleep bruxism and GER

1999 - 2000 The Changes in Dentofacial Morphology and Occlusion in Non-growing Subjects

1998 - 1999 若年者の顎関節症患者の偏側咀嚼癖とブラキシズム癖に対する神経生理学的検討

1999 - Clinical study in implant anchorage

1999 - Bruxism in TMD patients

1999 - Calculation of pressnre to the TMJ

1996 - 1996 咀嚼時の頭部の動きと頚部の筋活動に与える咬合接触状態の影響について