Research theme for competitive and other funds (2)：
Molecular Mechanisms in cerebral Cortical Development.
Study on a novel factor that is involved in cytoskeletal reorganization
Koohy H, Bolland DJ, Matheson LS, Schoenfelder S, Stellato C, Dimond A, Várnai C, Chovanec P, Chessa T, Denizot J, Manzano Garcia R, Wingett SW, Freire-Pritchett P, Nagano T, Hawkins P, Stephens L, Elderkin S, Spivakov M, Fraser P, Corcoran AE, Varga-Weisz PD. Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells. Genome biology. 2018. 19. 1. 126
Nagano T, Lubling Y, Várnai C, Dudley C, Leung W, Baran Y, Mendelson Cohen N, Wingett S, Fraser P, Tanay A. Cell-cycle dynamics of chromosomal organization at single-cell resolution. Nature. 2017. 547. 7661. 61-67
Nagano T, Wingett SW, Fraser P. Capturing Three-Dimensional Genome Organization in Individual Cells by Single-Cell Hi-C. Methods in molecular biology (Clifton, N.J.). 2017. 1654. 79-97
Nagano T, Lubling Y, Yaffe E, Wingett SW, Dean W, Tanay A, Fraser P. Single-cell Hi-C for genome-wide detection of chromatin interactions that occur simultaneously in a single cell. Nature protocols. 2015. 10. 12. 1986-2003
Nagano T, Várnai C, Schoenfelder S, Javierre BM, Wingett SW, Fraser P. Comparison of Hi-C results using in-solution versus in-nucleus ligation. Genome biology. 2015. 16. 175