Rchr
J-GLOBAL ID：200901049337492514   Update date: Sep. 29, 2024

Kanemaki Masato

カネマキ マサト | Kanemaki Masato
Affiliation and department：
National Institute of Genetics Department of Chromosome Science

About National Institute of Genetics Department of Chromosome Science


Other affiliations (2)：
  • SOKENDAI  School of Life Science Department of Genetics   Professor
  • The University of Tokyo  Graduate School of Science, Department of Biological Sciences   Professor
Homepage URL  (2)： http://kanemaki-lab.sakura.ne.jp/jpn/ ,  https://www.nig.ac.jp/labs/MolFunc/Eng/
Research field  (3)： Applied molecular and cellular biology ,  Genetics ,  Molecular biology
Research keywords  (10)： Auxin-inducible degron ,  Genomic instability ,  Chromosome ,  Genomics ,  Genome editing ,  Protein degradation ,  DNA replication ,  DNA repair ,  Homologous recombination ,  Cell engineering
Research theme for competitive and other funds  (13)：
  • 2023 - 2028 オーキシンデグロン法によるタンパク質寿命操作
  • 2021 - 2025 細胞及び動物個体で迅速タンパク質分解を可能にするAID2法の発展的基盤技術の開発
  • 2022 - 2024 非ゲノム情報による複製開始領域と複製タイミング制御メカニズムの解明
  • 2020 - 2022 非ゲノム情報による複製開始点制御の解明
  • 2018 - 2021 Improvement of the AID technology through chemical biology approaches
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Papers (93)：
  • Hatsune Makino-Itou, Noriko Yamatani, Akemi Okubo, Makoto Kiso, Rieko Ajima, Masato T Kanemaki, Yumiko Saga. Establishment and characterization of mouse lines useful for endogenous protein degradation via an improved auxin-inducible degron system (AID2). Development, Growth & Differentiation. 2024. 66. 7. 384-393
  • Yuki Hatoyama, Moutushi Islam, Adam G Bond, Ken-Ichiro Hayashi, Alessio Ciulli, Masato T Kanemaki. Combination of AID2 and BromoTag expands the utility of degron-based protein knockdowns. EMBO Reports. 2024. 25. 9. 4062-4077
  • Kayo Hibino, Yuji Sakai, Sachiko Tamura, Masatoshi Takagi, Katsuhiko Minami, Toyoaki Natsume, Masa A Shimazoe, Masato T Kanemaki, Naoko Imamoto, Kazuhiro Maeshima. Single-nucleosome imaging unveils that condensins and nucleosome-nucleosome interactions differentially constrain chromatin to organize mitotic chromosomes. Nature Communications. 2024. 15. 1. 7152-7152
  • Rebecca M Jones, Joaquin Herrero Ruiz, Shaun Scaramuzza, Sarmi Nath, Chaoyu Liu, Marta Henklewska, Toyoaki Natsume, Robert G Bristow, Francisco Romero, Masato T Kanemaki, et al. Characterizing replisome disassembly in human cells. iScience. 2024. 27. 7. 110260-110260
  • Xiaoxuan Zhu, Masato T Kanemaki. Replication initiation sites and zones in the mammalian genome: Where are they located and how are they defined?. DNA Repair. 2024. 141. 103713-103713
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Patents (12)：
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Books (14)：
  • ヒトの減数分裂期相同組換えにおいて環状DNAが生じる!?(実験医学 News & Hot Paper Digest)
    羊土社 2022 ISBN:9784758125567
  • High-efficient protein knockdown by a new generation of the auxin-inducible degron technology, AID2
    2021
  • Targeted protein degradation by use of a degron technology
    2021
  • ゲノム編集技術を応用した製品開発とその実用化
    技術情報協会 2021
  • Protein knockdown by the use of the auxin-inducible degron technology
    2020 ISBN:9784758125352
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Lectures and oral presentations  (62)：
  • Targeted protein degradation with the power of plant
    (MBSJ2023 Symposium (Synthetic biotechnology and beyond) 2023)
  • Replication initiation in human cells
    (2023)
  • 改良オーキシンデグロン AID2 を利用して、 ヒト細胞の DNA 複製機構を理解する
    (RNA Frontier meeting 2023 2023)
  • The mechanism defining replication initiation zones in human cells
    (Cold Spring Harbor Meeting on Eukaryotic DNA Replication and Genome Maintenance 2023)
  • A targeted protein knockdown with the power of plants
    (2nd TPD Conference in Japan 2023)
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Education (3)：
  • 1998 - 2001 Chiba University Graduate School of Science and Technology PhD program
  • 1996 - 1998 Chiba University Graduate School of Science and Technology Master program
  • 1992 - 1996 Chiba University School of Science Department of Biology
Professional career (1)：
  • PhD (Chiba University)
Work history (8)：
  • 2022/04 - 現在 Department of Biological Sciences, Graduate School of Science, The University of Tokyo Interlocking faculty Professor (Interlocking faculty member)
  • 2016/04 - 現在 National Institute of Genetics Department of Chromosome Science Professor
  • 2013/10 - 2017/03 JST PRESTO fellow
  • 2010/10 - 2016/03 National Institute of Genetics Center for Frontier Research Associate Professor
  • 2006/07 - 2010/09 Osaka University School of Science, Department of Biological Sciences Assistant Professor
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Committee career (7)：
  • 2023/04 - 現在 The Genetics Society of Japan Delegate
  • 2023/01 - 現在 The Molecular Biology Society of Japan Trustee
  • 2021/01 - 現在 The Molecular Biology Society of Japan Career path committee
  • 2020/06 - 現在 Japan Society for Cell Biology Delegate
  • 2020 - 現在 The Journal of Biochemistry Associate Editor
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Awards (1)：
  • 2024/02 - Foundation for Promotion of Material Science and Technology of Japan Yamzaki Teiichi Prize
Association Membership(s) (5)：
The Japanese Society for Genome Editing ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  THE JAPANESE CANCER ASSOCIATION ,  THE GENETICS SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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