Kawasaki Yasushi

カワサキヤスシ | Kawasaki Yasushi

Affiliation and department：
Job title： Associate Professor

Research field (1)： Pathobiochemistry

Research keywords (3)： molecular biology , 分子腫瘍学 , molecular oncology

Research theme for competitive and other funds (6)：

2015 - 2018 The role of endoplasmic reticulum stress response in the development of atherosclerosis resulted from obesity and diabetes.
2012 - 2015 Genome-wide analysis of epigenetics involved in progression of overt diabetic nephropathy
2010 - 2011 Studies on action mechanism of protective effects of angiogenesis inhibitor against the diabetic nephropathy.
2005 - 2006 Analysis of anticancer and cytotoxic mechanism of an Aralia elata-derived antitumor protein, aralin.
ニューロン/グリア運命決定分子PRP19遺伝子の選択的スプライシング機構の解明

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Papers (10)：

Sei Yonezawa, Yasushi Kawasaki, Yasuhiro Natori, Akinori Sugiyama. Improvement of LXR-mediated lipid metabolism in nephrotic model kidney accompanied by suppression of inflammation and fibrosis. Biochemical and biophysical research communications. 2023. 666. 122-127
Sei Yonezawa, Mizuho Abe, Yasushi Kawasaki, Yasuhiro Natori, Akinori Sugiyama. Each liver X receptor (LXR) type has a different purpose in different situations. Biochemical and biophysical research communications. 2019. 508. 1. 92-96
Masahiro Yamashita, Masahito Ogasawara, Yasushi Kawasaki, Miyuki Niisato, Heisuke Saito, Shuya Kasai, Chihaya Maesawa, Makoto Maemondo, Kohei Yamauchi. Deficiency of protein-L-isoaspartate (D-aspartate) O-methyl-transferase expression under endoplasmic reticulum stress promotes epithelial mesenchymal transition in lung adenocarcinoma. Oncotarget. 2018. 9. 17. 13287-13300
Nobutaka Ogasawara, Tamami Kudo, Masaki Sato, Yasushi Kawasaki, Sei Yonezawa, Satoru Takahashi, Yohei Miyagi, Yasuhiro Natori, Akinori Sugiyama. Reduction of Membrane Protein CRIM1 Decreases E-Cadherin and Increases Claudin-1 and MMPs, Enhancing the Migration and Invasion of Renal Carcinoma Cells. Biological & pharmaceutical bulletin. 2018. 41. 4. 604-611
Yasushi Kawasaki, Eriko Yokobayashi, Kentaro Sakamoto, Eri Tenma, Haruka Takaki, Yuki Chiba, Tomomi Otashiro, Mai Ishihara, Sei Yonezawa, Akinori Sugiyama, et al. Angiostatin prevents IL-1β-induced down-regulation of eNOS expression by inhibiting the NF-κB cascade. Journal of pharmacological sciences. 2015. 129. 3. 200-4

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MISC (77)：

米澤正, 林純衣, 小出裕之, 川崎靖, 杉山晶規, 浅井知浩. Development of tubulointerstitial-targeting drug delivery system in Zucker Diabetic Fatty Rat. 日本薬学会年会要旨集(Web). 2021. 141st
杉山晶規, 斎藤結, 小笠原信敬, 川崎靖, 米澤正, 名取泰博. 鉄キレート剤デフェロキサミンは腎がん細胞の浸潤・転移能を促進する. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
鶴見嵯枝子, 川崎靖, 佐々木瑞季, 勝又ゆき, 千田玲音, 大久保櫻, 今村仁美, 佐々木彩香, 米澤正, 名取泰博, et al. メタボリックシンドローム環境下の腎糸球体血管内皮細胞で生じるDNAメチル化変化. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
勝又ゆき, 野里佳世, 熊谷美穂, 佐々木瑞希, 鶴見嵯枝子, 川崎靖, 米澤正, 名取泰博, 杉山晶規. 尿細管上皮細胞における脂質の蓄積による細胞障害機序. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
千葉夏海, 本多里奈, 川崎靖, 米澤正, 名取泰博, 杉山晶規. ACHN細胞に対するmetforminの効果について. 日本薬学会年会要旨集(CD-ROM). 2019. 139th

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Lectures and oral presentations (15)：

Mechanisms of lipid accumulation and cytotoxicity by fatty acid uptake in renal tubular epithelial cells
(2019)
Role of ADRa1A in palmitic acid induced hepatocyte injury.
(2019)
Usefulness of serum and urinary lymphangiogenic growth factor VEGF-D as a potential biomarker for diabetic nephropathy in diabetes mellitus patients.
(2018)
Forced expression of antisense 14-3-3s RNA suppresses tumor cell growth in vitro and in vivo
(Gordon Research Conference 2008)
Forced expression of antisense 14-3-3s RNA suppresses tumor cell growth in vitro and in vivo
(Gordon Research Conference 2008)

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Education (4)：

- 2004 Tokyo University of Science Graduate School of Industrial Science and Technology
- 2004 Tokyo University of Science Graduate School, Division of Engineering Science
- 1999 Tokyo University of Science Faculty of Industrial Science and Technology Biological Science and Technology
- 1999 Tokyo University of Science Faculty of Engineering Science

Professional career (1)：

Ph. D. (Tokyo University of Science)

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