Rchr
J-GLOBAL ID:200901074911542236   Update date: Mar. 19, 2024

Muramatsu Shin-ichi

ムラマツ シンイチ | Muramatsu Shin-ichi
Affiliation and department:
Job title: Visiting Professor
Research field  (2): Neuroscience - general ,  Neurology
Research keywords  (14): 包括脳ネットワーク ,  脳プロ ,  Gene therapy ,  Adeno-associated virus ,  ES細胞 ,  レビー小体 ,  アルツハイマー病 ,  大脳基底核 ,  PET ,  カニクイサル ,  アデノ随伴ウイルス ,  ドパミン ,  パーキンソン病 ,  遺伝子治療
Research theme for competitive and other funds  (17):
  • 2022 - 2025 多機能化一本鎖抗体によるアミロイドβ凝集体細胞内スワイプ療法の開発
  • 2020 - 2023 異常凝集体に対する体外診断法開発によるアルツハイマー病の早期診断と病態解明
  • 2016 - 2018 Development of next-generation gene therapy and intracellular immunotherapy for Alzheimer's disease
  • 2015 - 2018 Protective effects of Shati/Nat8l on the dysfunction induced by addictive drugs
  • 2015 - 2017 A new mice model of bipolar disease for the drug developments
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Papers (362):
  • Shin-Ichi Muramatsu. AAV vectors advance cardiac gene therapy while overcoming challenges. International journal of cardiology. 2024. 400. 131704-131704
  • Yoshiaki Tanaka, Rina Takagi, Shingen Mitou, Machiko Shimmura, Tetsuya Hasegawa, Jota Amarume, Masami Shinohara, Yasushi Kageyama, Tomohiko Sasase, Takeshi Ohta, et al. Protective Effect of Pemafibrate Treatment against Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats. Biological & pharmaceutical bulletin. 2024
  • Hajime Miyanishi, Shiori Suga, Kazuyuki Sumi, Miho Takakuwa, Naotaka Izuo, Takashi Asano, Shin-Ichi Muramatsu, Atsumi Nitta. The Role of GABA in the Dorsal Striatum-Raphe Nucleus Circuit Regulating Stress Vulnerability in Male Mice with High Levels of Shati/Nat8l. eNeuro. 2023. 10. 10
  • Masao Noda, Ryota Koshu, Mari Shimada Dias, Chizu Saito, Naomi Takino, Mika Ito, Hidekane Yoshimura, Makoto Ito, Shin-Ichi Muramatsu. Enhanced Cochlear Transduction by AAV9 with High-Concentration Sucrose. Human gene therapy. 2023. 34. 19-20. 1064-1071
  • Yuji Kashiwakura, Kazuhiro Endo, Atsushi Ugajin, Tomohiro Kikuchi, Shuji Hishikawa, Hitoyasu Nakamura, Yuko Katakai, Nemekhbayar Baatartsogt, Takafumi Hiramoto, Morisada Hayakawa, et al. Efficient Gene Transduction in Pigs and Macaques with the Engineered AAV Vector AAV.GT5 for Hemophilia B Gene Therapy. Molecular Therapy - Methods & Clinical Development. 2023. 30. 502-514
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MISC (214):
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Patents (5):
Professional career (1):
  • MD
Work history (6):
  • 2024/04 - 現在 Jichi Medical University School of Medicine Visiting Professor
  • 2008/11 - 現在 Jichi Medical University Division of Neurology, Department of Medicine
  • 2019/04 - 2024/03 Jichi Medical University Division of Neurological Gene Therapy, Center for Open Innovation Professor
  • 2019/04 - 2024/03 The Institute of Medical Science, The University of Tokyo Center for Gene & Cell Therapy Visiting Professor
  • 2014/11 - 2019/03 The Institute of Medical Science, The University of Tokyo Center for Gene & Cell Therapy Project Professor
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Committee career (2):
  • - 現在 日本遺伝子細胞治療学会 理事
  • - 2019/05 日本東洋医学会 理事
Awards (4):
  • 2019/03 - ヘルシー・ソサエティー賞
  • 2011/07 - Japan Society of Gene Therapy Takara Bio Award
  • 2009/06 - American Society of Gene Therapy Top Abstract
  • 2000/06 - Japan Society of Gene Therapy The 6th JSGT Award
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