Rchr
J-GLOBAL ID：200901086124372909   Update date: Jan. 07, 2025

Yasui Hiroyuki

ヤスイ ヒロユキ | Yasui Hiroyuki
Affiliation and department：
Kyoto Pharmaceutical University

About Kyoto Pharmaceutical University


Homepage URL  (1)： http://labo.kyoto-phu.ac.jp/taisya/
Research field  (4)： Clinical pharmacy ,  Pharmaceuticals - analytical and physicochemistry ,  Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - chemistry and drug development
Research keywords  (8)： 応用薬理学 ,  医療系薬学 ,  創薬化学 ,  物理系薬学 ,  医薬分子機能学 ,  Pharmacentical Environmental Science ,  Physical Pharmacology ,  Molecular Pharmacology
Research theme for competitive and other funds  (29)：
  • 2024 - 2027 Enhanced action of platinum-based anticancer drugs using gold-sulphur complexes with cancer stromal site occupancy as adjuvants
  • 2023 - 2026 Comprehensive Examination of Novel Risk Factors for Development of Lifestyle-related Diseases by Metallomics Analysis by Molecular Weight
  • 2020 - 2023 Pathological analysys and new therapeutic development for inflammatory bowel diseaseon on the molecular basis of fluctuant activity of zinc-requiring enzyme
  • 2017 - 2019 Development and application of novel chemical compounds to materialize the cancer theranostics
  • 2014 - 2017 Development of orally active zinc complexes enhancing and controlling the function of endogenous insulin as a novel anti-diabetic candidate
Show all
Papers (284)：
  • Ryota Saito, Yuki Naito, Yutaka Yoshikawa, Hiroyuki Yasui, Shoko Kikkawa, Huiyeong Ju, Rintaro Ohba, Tae Miyamoto, Shogo Sano, Kazuya Maeda, et al. Synthesis, crystal structure, and insulin-mimetic activity of zinc(ii) complexes with 4-alkyl- and 4,5-dialkyl-3-hydroxythiazole-2(3H)-thiones as a new class of hypoglycemic agent candidates. New Journal of Chemistry. 2025
  • Nagisa Ishida, Yuuki Nishida, Shohei Hamada, Hiroyuki Yasui, Takumi Furuta, Yusuke Kobayashi. Brønsted Acid-Stibine Oxide Complexes as Organocatalysts for the Activation of Alkenes. Asian Journal of Organic Chemistry. 2024
  • Yuto Kondo, Hiroyuki Kimura, Mamiko Tanaka, Yasunao Hattori, Hidekazu Kawashima, Kazuhiro Takahashi, Hiroyuki Yasui. Mechanistic Insights into the Effect of Sodium Iodide on Copper-Mediated Iododeboronation. Chemistry - A European Journal. 2024
  • Yukina Nishito, Yoshiki Kamimura, Shino Nagamatsu, Nao Yamamoto, Hiroyuki Yasui, Taiho Kambe. Zinc and manganese homeostasis closely interact in mammalian cells. The FASEB Journal. 2024. 38. 7
  • Yoshiki Yamamoto, Yukako Yasui, Kohei Yamamoto, Taishi Hibino, Hiroyuki Yasui, Toshihiko Ishizaka, Yoshihiko Ogawa. Rapid measurement of plasma voriconazole concentration by high performance liquid chromatography in the hospital: therapeutic drug monitoring and medical care support for outpatients. Japanese Journal of Chemotherapy. 2024. 72. 1. 9-16
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MISC (230)：
  • 面川真里奈, 木村寛之, 木村寛之, 初川雄一, 河嶋秀和, 塚田和明, 屋木裕亮, 内藤行喜, 安井裕之. Synthesis and biological evaluation of a novel sugar-conjugated platinum complex having a tumor-targeting effect and 191Pt labeled complex. 日本薬学会年会要旨集(Web). 2024. 144th
  • 安井 友佳子, 山本 圭城, 石坂 敏彦, 安井 裕之. ボリコナゾールの血中トラフ濃度の個体間変動に影響する因子の探索と遺伝子多型情報を用いない血中濃度予測式の提案. TDM研究. 2023. 40. 2. 197-197
  • 近藤悠斗, 木村寛之, 河嶋秀和, 服部恭尚, 安井裕之. Copper-mediated one-pot radioiodination on a resin. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 面川真里奈, 木村寛之, 初川雄一, 河嶋秀和, 安井裕之. Evaluation of biodistribution of a novel sugar-conjugated platinum complex and its complex labeled with 191Pt in mice. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 古川武典, 木村寛之, 志賀智華, 吉村茜音, 屋木祐亮, 屋木祐亮, 河嶋秀和, 安井裕之. Research on development of [125I]EFT-7 as an imaging tracer targeting Erythropoietin-producing hepatocellular receptor A2. 日本薬学会年会要旨集(Web). 2023. 143rd
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Patents (12)：
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Books (25)：
  • 実証医薬分析科学 : 基礎から臨床への展開を視野に入れて...
    京都廣川書店 2024 ISBN:9784910844329
  • 酸化ストレスの医学(改訂第3版)
    診断と治療社 2024 ISBN:9784787826206
  • コンパス分析化学[電子版付](改訂第3版増補)
    南江堂 2024 ISBN:9784524404551
  • 化学物質の分析
    東京化学同人 2022 ISBN:9784807917280
  • コンパス分析化学(改訂第3版)
    南江堂 2021 ISBN:9784524403868
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Lectures and oral presentations  (164)：
  • 潰瘍性大腸炎モデルマウスにおける63Cuおよび65Cuの同位体分析による病態診断への可能性
    (第35回日本微量元素学会学術集会 2024)
  • 糖化反応に起因する耐糖能異常ならびに腎機能障害に対する亜鉛化合物の有用性
    (第35回日本微量元素学会学術集会 2024)
  • Improving the Efficiency of Copper-Mediated Iododeboronation Based on Special Reaction Conditions in Radioiodination Reactions
    (33rd Symposium on Role of Metals in Biological Reactions, Biology and Medicine 2024)
  • Creation and biological evaluation of a novel sugar-platinum complex for cancer therapy
    (33rd Symposium on Role of Metals in Biological Reactions, Biology and Medicine 2024)
  • Development of Molecular imaging probes targeting adrenal aldosterone synthase (CYP11B2)
    (33rd Symposium on Role of Metals in Biological Reactions, Biology and Medicine 2024)
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Education (3)：
  • 1991 - 1995 Kyoto University
  • 1989 - 1991 Kyoto University
  • 1985 - 1989 Kyoto University Faculty of Pharmaceutical Sciences
Professional career (2)：
  • Master of Science.
  • Ph. D
Work history (4)：
  • 2007/10 - 現在 Kyoto Pharmaceutical University Pharmaceutical Sciences
  • 2007/04 - 2007/09 Kyoto Pharmaceutical University Pharmaceutical Sciences
  • 2004/04 - 2007/03 Kyoto Pharmaceutical University Pharmaceutical Sciences
  • 1995/04 - 2004/03 Kyoto Pharmaceutical University Pharmaceutical Sciences
Awards (1)：
  • 2000 - 日本薬学会近畿支部奨励賞
Association Membership(s) (11)：
カロテノイド研究会 ,  JAPAN SOCIETY OF COORDINATION CHEMISTRY ,  The Japanese Peptide Society ,  日本TDM学会 ,  SOCIETY FOR FREE RADICAL RESEARCH JAPAN ,  THE SOCIETY OF ELECTRON SPIN SCIENCE AND TECHNOLOGY ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  JAPAN SOCIETY FOR BIOMEDICAL RESEARCH ON TRACE ELEMENTS ,  THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  日本分析化学会
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