Rchr
J-GLOBAL ID:200901086739190711   Update date: Apr. 03, 2024

Matsumura Shigenobu

マツムラ シゲノブ | Matsumura Shigenobu
Affiliation and department:
Job title: Researcher
Research field  (4): Clinical pharmacy ,  Physiology ,  Food sciences ,  Animals: biochemistry, physiology, behavioral science
Research keywords  (6): 代謝 ,  運動 ,  脂肪 ,  味 ,  taste ,  fat
Research theme for competitive and other funds  (11):
  • 2023 - 2027 Neuronal mechanism of hyperphagia in High fat foods
  • 2021 - 2024 グリア系細胞におけるタイトジャンクションの意義と神経病態への関与
  • 2019 - 2023 油脂の嗜好性が肥満を誘導する機構と肥満を抑制する機構
  • 2018 - 2021 Mechanism of obesity in female CRTC1 Knockout mice
  • 2016 - 2020 Obesity induced by fat palatability and mental stress
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Papers (94):
  • Jungin Kwon, Yu-Sheng Yeh, Satoko Kawarasaki, Hiroto Minamino, Yoshihito Fujita, Yuko Okamatsu-Ogura, Haruya Takahashi, Wataru Nomura, Shigenobu Matsumura, Rina Yu, et al. Mevalonate biosynthesis pathway regulates the development and survival of brown adipocytes. iScience. 2023. 26. 3. 106161-106161
  • Haomin Yan, Tsutomu Sasaki, Hideaki Kanki, Yoshiyuki Hirata, Kumiko Nishiyama, Sunao Hisada, Shigenobu Matsumura, Yasuo Nagaoka, Takaaki Sumiyoshi, Seiichi Nagano, et al. MDMX elevation by a novel Mdmx-p53 interaction inhibitor mitigates neuronal damage after ischemic stroke. Scientific reports. 2022. 12. 1. 21110-21110
  • Shigenobu Matsumura, Motoki Miyakita, Haruka Miyamori, Satomi Kyo, Fuka Ishikawa, Tsutomu Sasaki, Tomoki Jinno, Jin Tanaka, Kotomi Fujita, Takumi Yokokawa, et al. CRTC1 deficiency, specifically in melanocortin-4 receptor-expressing cells, induces hyperphagia, obesity, and insulin resistance. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2022. 36. 12. e22645
  • Naoki Harada, Mai Okuyama, Yoshiaki Teraoka, Yumi Arahori, Yoh Shinmori, Hiroko Horiuchi, Paula B. Luis, Akil I. Joseph, Tomoya Kitakaze, Shigenobu Matsumura, et al. Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin. npj Science of Food. 2022. 6. 1
  • Shigenobu Matsumura, Motoki Miyakita, Haruka Miyamori, Satomi Kyo, Daisuke Shima, Takumi Yokokawa, Fuka Ishikawa, Tsutomu Sasaki, Tomoki Jinno, Jin Tanaka, et al. Stimulation of Gs signaling in MC4R cells by DREADD increases energy expenditure, suppressing food intake, and increasing locomotor activity in mice. American Journal of Physiology-Endocrinology and Metabolism. 2022
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MISC (114):
Patents (2):
Books (5):
  • おいしさの科学とビジネス展開の最前線
    シーエムシー出版 2017
  • 油脂のおいしさと科学
    (株)エヌ・ティー・エス 2016
  • Fat Detection: Taste, Texture, and Post Ingestive Effects
    CRC Press 2010
  • 運動と栄養と食品
    朝倉書店 2006
  • Molecular Medicine Vol. 41 No. 10
    中山書店 2005
Lectures and oral presentations  (4):
  • 油のおいしさとその科学的メカニズム
    (第20回 日本健康医学会総会 2010)
  • Ligand specificities to putative fat receptor candidates CD36 and GPR120 and licking behavior corresponding to the ligands in mice
    (AChemS 2009 Annual Meeting XXXI 2009)
  • INCREASE IN TRANSFORMING GROWTH FACTOR-BETA IN THE BRAIN DURING INFECTION IS RELATED TO FEVER, NOT DEPRESSION OF SPONTANEOUS MOTOR ACTIVITY
    (The 3rd international siymposium on physiology and pharmacology of thermoregulation 2009)
  • The palatability of long-chain fatty acids to mice
    (The 6th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception 2008)
Professional career (1):
  • 博士(農学) (京都大学)
Association Membership(s) (3):
日本生理学会 ,  日本栄養食糧学会 ,  日本農芸化学会
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