Art
J-GLOBAL ID：200902123849956279   Reference number：98A0881890

Human Buprenorphine N-Dealkylation Is Catalyzed by Cytochrome P450 3A4.

ヒトにおけるブプレノルフィンN-脱アルキル化はチトクロームP450 3A4により触媒される
Author (7)：
KOBAYASHI K

About KOBAYASHI K

(Showa Univ.)

About Showa Univ.

, 
YAMAMOTO T

About YAMAMOTO T

(Showa Univ.)

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, 
CHIBA K

About CHIBA K

(Chiba Univ.)

About Chiba Univ.

, 
TANI M

About TANI M

(Daiichi Pure Chemicals Co. Ltd.)

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, 
SHIMADA N

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(Daiichi Pure Chemicals Co. Ltd.)

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, 
ISHIZAKI T

About ISHIZAKI T

(Daiichi Pure Chemicals Co. Ltd.)

About Daiichi Pure Chemicals Co. Ltd.

, 
KUROIWA Y

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(Showa Univ.)

About Showa Univ.


Material：
Drug Metabolism and Disposition  (Drug Metab Dispos)

About Drug Metabolism and Disposition


Volume： 26  Issue： 8  Page： 818-821  Publication year： Aug. 1998 
JST Material Number： H0232A  ISSN： 0090-9556  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)
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human

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,...
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hydroxylation

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,...
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JST classification (2)：
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Category name(code) classified by JST.
Basic research of addictive analgesics and narcotics 
(GW03080Z)

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,  Enzyme physiology 
(EJ02020P)

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Substance index (2)：
Substance index
Chemical Substance indexed to the Article.
Buprenorphine

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, 
Norbuprenorphine

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Terms in the title (5)：
Terms in the title
Keywords automatically extracted from the title.
ヒト

About ヒト

, 
ブプレノルフィン

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, 
脱アルキル化

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, 
チトクロームP450

About チトクロームP450

, 
触媒

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