Art

J-GLOBAL ID：200902133455548014   Reference number：96A0705228

Chlovalicin, a New Cytocidal Antibiotic Produced by Sporothrix sp. FO-4649. II. Physicochemical Properties and Structural Elucidation.

クロバリシン,Sporothrix sp.FO-4649が生産する殺細胞性新抗生物質 II 物理化学的性質と構造解析

Author (8)： TAKAMATSU S (Kitasato Univ., Tokyo, JPN) ,  KIM Y-P (Kitasato Univ., Tokyo, JPN) ,  KOMIYA T (Kitasato Univ., Tokyo, JPN) ,  SUNAZUKA T (Kitasato Univ., Tokyo, JPN) ,  HAYASHI M (Kitasato Univ., Tokyo, JPN) ,  TANAKA H (Kitasato Univ., Tokyo, JPN) ,  KOMIYAMA K (Kitasato Univ., Tokyo, JPN) ,  OMURA S (Kitasato Univ., Tokyo, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 49  Issue： 7  Page： 635-638  Publication year： Jul. 1996 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Hyphomycetes ,...
Semi thesaurus term： クロバリシン ,...

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JST classification (2)： Basic research of antitumor(=antineoplastic)antibiotics  (GX05040Y) ,  Antibiotic fermentation  (GX03000S)

Substance index (2)： Ovalicin ,  Chlovalicin

Reference (16)：

• 1) YAMASAKI, K.; T. TAGA, Y. HIRATA, H. YAWATA, Y. KAWANISHI, B. SEED, T. TANIGUCHI, T. HIRANO & T. KISHIMOTO: Cloning and expression of the human interleukin-6 (BSF-2/IFNb) receptor. Science 241: 825-828, 1988
• 2) STRASSMANN, G.; M. FOMG, J. S. KENNEY & C. O. JACOB: Evidence for the involvement of interleukin 6 in experimental cancer cachexia. J. Clin. Invest. 89: 1681 - 1684, 1992
• 4) SODA, K.; M. KAWAKAMI, A. KASHII & M. MIYATA: Characterization of mice bearing subclones of colon 26 adenocarcinoma disqualifies interleukin-6 as the sole inducer of cachexia. Jpn. J. Cancer Res. 85: 1124-1130, 1994
• 5) YASUMOTO, K.; N. MUKAIDA, A. HARADA, K. KUNO, M. AKIYAMA, E. NAKASHIMA, N. FUJIOKA, M. MAI, T. KASAHARA, K. FUJIMOTO-OUCHI, K. MORI, Y. TANAKA & K. MATSUSHIMA: Molecular analysis of the cytokine network involved in cachexia in colon 26 adenocarcinoma-bearing mice. Cancer Research 55: 921-927, 1995
• 6) HAYASHI, M.; Y.-P. KIM, S. TAKAMATSU, T. KOMIYA, R. MASUMA, S. PREEPRAME, K. KOMIYAMA, H. TANAKA & S. OMURA: Chlovalicin, a new cytocidal antibiotic produced by Sporothrix sp. FO-4649. I. Taxonomy, fermentation, isolation and biological activities. J. Antibiotics 49: 631-634, 1996

Terms in the title (6)： Sporothrix ,  FO ,  細胞性 ,  抗生物質 ,  物理化学的性質 ,  構造解析