Art

J-GLOBAL ID：200902139698167050   Reference number：99A0324902

Structure-specific Inhibition of Cholesteryl Ester Transfer Protein by Azaphilones.

アザフィロン類は構造-特異的に,コレステリルエステル転移蛋白質を抑制する

Author (9)： TOMODA H (Kitasato Inst., Tokyo, JPN) ,  MATSUSHIMA C (Kitasato Univ., Tokyo, JPN) ,  TABATA N (Kitasato Inst., Tokyo, JPN) ,  NAMATAME I (Kitasato Univ., Tokyo, JPN) ,  TANAKA H (Kitasato Univ., Tokyo, JPN) ,  BAMBERGER M J (Pfizer Inc., Connecticut, USA) ,  ARAI H (Univ. Tokyo, Tokyo, JPN) ,  FUKAZAWA M (Univ. Tokyo, Tokyo, JPN) ,  OMURA S (Kitasato Inst., Tokyo, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 52  Issue： 2  Page： 160-170  Publication year： Feb. 1999 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *enzyme inhibitor ,...
Semi thesaurus term： *cholesterol esterase ,...

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JST classification (2)： Pharmacology of antibiotics in general  (GX05010R) ,  Structure-activity relationship of drugs  (GV01050B)

Substance index (13)： Sclerotiorin ,  Rubrorotiorin ,  Ochrephilone ,  Sclerotioramine ,  Isochromophilone I ,  Isochromophilone II ,  Chaetoviridin A ,  Chaetoviridin B ,  Rotiorin ,  Deacetylsclerotiorin ,  Isochromophilone III ,  Isochromophilone V ,  Isochromophilone VI

Reference (44)：

• 1) TALL, A. R.: Plasma cholesteryl ester transfer protein. J. Lipid Res. 34: 1255-1274, 1993
• 2) BARTER, P. & K.-A. RYE: Cholesteryl ester transfer protein: its role in plasma lipid transport. Clin. Exp. Pharmacol. Physiol. 21: 663-672, 1994
• 3) LAGROST, L.: Regulation of cholesteryl ester transfer protein (CETP) activity: review of in vitro and in vivo studies. Biochim. Biophys. Acta 1215: 209-236, 1994
• 4) HESLER, C. B.; T. L. SWENSON & A. R. TALL: Purification and characterization of a human plasma cholesteryl ester transfer protein. J. Biol. Chem. 262: 2275-2282, 1987
• 5) JARNAGIN, A. S.; W. KOHR & C. FIELDING: Isolation and specificity of a Mr 74,000 cholesteryl ester transfer protein from human plasma. Proc. Natl. Acad. Sci. USA 84: 1854-1857,1987

Terms in the title (2)： コレステリルエステル ,  蛋白質