Art

J-GLOBAL ID：200902152846085552   Reference number：01A0628540

Enantioselective Total Synthesis of a Potent Antitumor Antibiotic, Fredericamycin A.

強力な抗腫よう抗生物質フレデリカマイシンAのエナンチオ選択的全合成

Author (8)： KITA Y (Osaka Univ., Osaka, JPN) ,  HIGUCHI K (Osaka Univ., Osaka, JPN) ,  YOSHIDA Y (Osaka Univ., Osaka, JPN) ,  IIO K (Osaka Univ., Osaka, JPN) ,  KITAGAKI S (Osaka Univ., Osaka, JPN) ,  UEDA K (Osaka Univ., Osaka, JPN) ,  AKAI S (Osaka Univ., Osaka, JPN) ,  FUJIOKA H (Osaka Univ., Osaka, JPN)
Material： Journal of the American Chemical Society  (J Am Chem Soc)
Volume： 123  Issue： 14  Page： 3214-3222  Publication year： Apr. 11, 2001 
JST Material Number： C0254A  ISSN： 0002-7863  CODEN： JACSAT  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： asymmetric synthesis ,...

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=01A0628540&from=J-GLOBAL&jstjournalNo=C0254A") }}

JST classification (2)： Synthesis of antibiotics  (GX04000Z) ,  Other condensed derivatives of pyridine  (CF07097Y)

Substance index (27)： Fredericamycin A ,  2,3,4,5-Tetrahydro-1H-benzo[e]indene-1-one ,  rac-Benzoic acid 3aβ^*,9bβ^*-epoxy-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalene-1β^*-yl ester ,  rac-Acetic acid 3aβ^*,9bβ^*-epoxy-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalene-1β^*-yl ester ,  rac-Benzoic acid 3aα^*,9bα^*-epoxy-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalene-1β^*-yl ester ,  rac-Acetic acid 3aα^*,9bα^*-epoxy-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalene-1β^*-yl ester ,  rac-4-Nitrobenzoic acid 3aα^*,9bα^*-epoxy-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalene-1β^*-yl ester ,  rac-Benzoic acid (1R^*)-5-oxospiro[cyclopentane-1,1′-indan]-2β^*-yl ester ,  rac-Acetic acid (1R^*)-5-oxospiro[cyclopentane-1,1′-indan]-2β^*-yl ester ,  rac-4-Nitrobenzoic acid (1R^*)-5-oxospiro[cyclopentane-1,1′-indan]-2β^*-yl ester ,  (1R)-3aα,9bα-Epoxy-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalene-1α-ol ,  Benzoic acid 3aα,9bα-epoxy-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalene-1β-yl ester ,  2,4-Cyclopentadiene-1-carboxylic acid (1S)-3aα,9bα-epoxy-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalene-1β-yl ester ,  Benzoic acid (1R)-5-oxospiro[cyclopentane-1,1′-indan]-2β-yl ester ,  2,4-Cyclopentadiene-1-carboxylic acid (1R,2S)-5-oxospiro[cyclopentane-1,1′-[1H]indene]-2β-yl ester ,  (R)-Dispiro[indan-1,1′-cyclopentane-5′,2′′-[1,3]dioxolan]-2′-one ,  2-Methoxy-4,6-dimethyl-3-pyridinecarboxylic acid methyl ester ,  8-Methyl-10,11-dimethoxy-11b-hydroxy-2,3,3a,4,5,11b-hexahydro-9-aza-1H-cyclopenta[a]anthracene-1-one ,  8-Methyl-10,11-dimethoxy-2,3,4,5-tetrahydro-9-aza-1H-cyclopenta[a]anthracene-1-one ,  (1S)-1′,9′-Dimethoxy-3-(phenylsulfinyl)-3′-methyl-6′,7′-dihydrospiro[3-cyclopentene-1,8′-[8H]cyclopenta[g]isoquinoline]-2,5-dione ,  4,5,6,7-Tetramethoxyisochroman-1,3-dione ,  4,5,6,8-Tetramethoxyisochroman-1,3-dione ,  (2S)-1′,5,6,8,9,9′-Hexamethoxy-3′-methyl-4-hydroxy-1,3,6′,7′-tetrahydrospiro[2H-cyclopenta[b]naphthalene-2,8′-[8H]cyclopenta[g]isoquinoline]-1,3-dione ,  (2R)-1′,4,5,6,8,9′-Hexamethoxy-3′-methyl-9-hydroxy-1,3,6′,7′-tetrahydrospiro[2H-cyclopenta[b]naphthalene-2,8′-[8H]cyclopenta[g]isoquinoline]-1,3-dione ,  (2S)-1′,4,5,6,8,9,9′-Heptamethoxy-3′-methyl-1,3,6′,7′-tetrahydrospiro[2H-cyclopenta[b]naphthalene-2,8′-[8H]cyclopenta[g]isoquinoline]-1,3-dione ,  (2R)-1′,4,5,6,8,9,9′-Heptamethoxy-3′-methyl-1,3,6′,7′-tetrahydrospiro[2H-cyclopenta[b]naphthalene-2,8′-[8H]cyclopenta[g]isoquinoline]-1,3-dione ,  (2S)-4,5,6,8,9,9′-Hexamethoxy-3′-formyl-1,1′,2′,3,6′,7′-hexahydrospiro[2H-cyclopenta[b]naphthalene-2,8′-[8H]cyclopenta[g]isoquinoline]-1,1′,3-trione

Terms in the title (3)： 抗腫よう抗生物質 ,  フレデリカマイシンA ,  全合成