Art

J-GLOBAL ID：200902168773579555   Reference number：96A0323918

Pyripyropenes, Novel ACAT Inhibitors Produced by Aspergillus fumigatus. IV. Structure Elucidation of Pyripyropenes M to R.

ピリピロペン類,Aspergillus fumigatusが生産する新規ACAT阻害剤 IV ピリピロペンMからRの構造解析

Author (7)： TOMODA H (Kitasato Univ., Tokyo, JPN) ,  TABATA N (Kitasato Univ., Tokyo, JPN) ,  YANG D-J (Kitasato Univ., Tokyo, JPN) ,  NAMATAME I (Kitasato Univ., Tokyo, JPN) ,  TANAKA H (Kitasato Univ., Tokyo, JPN) ,  OHMURA S (Kitasato Univ., Tokyo, JPN) ,  KANEKO T (Pfizer Inc., CT, USA)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 49  Issue： 3  Page： 292-298  Publication year： Mar. 1996 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： antibiotics ,...
Semi thesaurus term： cholesterol acyltransferase ,...

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JST classification (2)： Antibiotics in general  (GX01000E) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (6)： Pyripyropene M ,  Pyripyropene N ,  Pyripyropene O ,  Pyripyropene P ,  Pyripyropene Q ,  Pyripyropene R

Reference (9)：

• 1)OMURA, S.; H. TOMODA, Y. K. KIM & H. NISHIDA: Pyripyropenes, highly potent inhibitors of acyl-CoA: cholesterol acyltransferase produced by Aspergillus fumigatus. J. Antibiotics 46:1168-1169, 1993
• 2) TOMODA, H.; Y. K. KIM, H. NISHIDA, R. MASUMA & S. OMURA: Pyripyropenes, novel inhibitors of acyl-CoA: cholesterol acyltransferase produced by Aspergillus fumigatus. I. Production, isolation and biological properties. J. Antibiotics 47:148-153, 1994
• 3) KIM, Y. K.; H. TOMODA, H. NISHIDA, T. SUNAZUKA, R. OBATA & S. OMURA: Pyripyropenes, novel inhibitors of acyl-CoA: cholesterol acyltransferase produced by Aspergillus fumigatus. II. Structure elucidation of pyripyropenes A, B, C and D. J. Antibiotics 47:154-162, 1994
• 3) TOMODA, H.; N. TABATA, D.-J. YANG, H. TAKAYANAGI, H. NISHIDA & S. OMURA: Pyripyropenes, novel ACAT inhibitors produced by Aspergillus fumigatus. III. Structure elucidation of pyripyropenes E to L. Antibiotics 48:495-503, 1995
• 5) TOMODA, H.; H. NISHIDA, Y. K. KIM, R. OBATA, T. SUNAZUKA, S. OMURA, J. BORDNER, M. GUADLLANA, G. DORMER & A. B. SMITH III: Relative and absolute stereochemistry of pyripyropene A, a potent, bioavailable inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT). J. Am. Chem. Soc. 116:12097-12098, 1994

Terms in the title (4)： Aspergillus ,  ACAT ,  阻害剤 ,  構造解析